Associated Malformations in Infants With Cleft Lip and Palate: A Prospective, Population-based Study

Milerad, Josef; Larson, Ola; Hagberg, Catharina; Ideberg, Margareta

doi:10.1542/peds.100.2.180

Cited by 226 publications

(216 citation statements)

References 5 publications

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“…Recent research would indicate that 21-37% of patients might have other anomalies including: cardiovascular (24-51%), musculoskeletal, facial dysmorphia or genitourinary system disturbance 8,9 . Children with associated anomalies are more likely to have combined CLP or cleft palate, rather than cleft lip alone 8 . They are often of lower birth weight 10 .…”

Section: Associated Anomaliesmentioning

confidence: 99%

Management of Children With Cleft Lip and Palate: A Review Describing the Application of Multidisciplinary Team Working in This Condition Based Upon the Experiences of a Regional Cleft Lip and Palate Centre in the United Kingdom

Hodgkinson

Brown

Duncan

et al. 2005

Fet. Matern. Med. Rev.

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Section: Associated Anomaliesmentioning

confidence: 99%

Management of Children With Cleft Lip and Palate: A Review Describing the Application of Multidisciplinary Team Working in This Condition Based Upon the Experiences of a Regional Cleft Lip and Palate Centre in the United Kingdom

Hodgkinson

Brown

Duncan

et al. 2005

Fet. Matern. Med. Rev.

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“…The Cleft lip and/or palate (CLP) is considered to be the most common congenital anomaly present in the craniofacial region (Alkofide, 2008); it has been reported as a solitary finding, or associated with other malformations in over 250 syndromes (Horswell, 1991) that occurs particularly in the central nervous, cardiac, and musculoskeletal systems (Milerad et al, 1997;Horswell).…”

Section: Introductionmentioning

confidence: 99%

Frequency of Ponticulus Posticus, Sella Turcica Bridge and Clinoid Enlargement in Cleft Lip and Palate Peruvian Patients: A Comparative Study with Non-Cleft Patients

Pérez

Chávez

2015

Int. J. Morphol.

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SUMMARY:The aims of this study were to determine the frequency of the Ponticulus posticus (PP) in the C1 vertebra and the Sella Turcica Bridge (STB) and Clinoid enlargement (CLEN) variants in two samples of Peruvian cleft lip and palate patients (CLP), determine if there are significant differences between sexes and compare the results with two samples of non-cleft controls. The digital images of the lateral cephalometric radiography of 163 and 150 CLP patients were utilized to determine the frequency of PP and, STB-CLEN respectively. The controls were composed of 1056 and 417 radiography of non-cleft patients. The chi-square statistic was utilized to determine if there were significant differences between genres for the CLP patients, and between the CLP and control samples. The confidence level was set at p<0.05. The frequency of PP (partial and complete) in CLP patients was 11.04% (18 cases) and 6.13% (10 cases) respectively; both of them were more frequent in males and there were no significant differences between sexes and between the CLP and control groups (p>0.05). The frequency of STB and CLEN in CLP patients was 6% (9 cases) and 8.7% (13 cases) respectively; both of them were more frequent in males and there were no significant differences between sexes and between the CLP and control samples for the STB (p>0.05). The frequency of CLEN was significantly lower (p<0.05) in the cleft group and in the female cleft group when compared to the control group. The frequencies of the Ponticulus Posticus, Sella Turcica Bridge and Clinoid Enlargement were similar to the control group and should not be considered as Cleft Lip and Palate associated anomalies; the frequency of the Clinoid Enlargement was significantly lower in cleft patients and this could be confirmed through studies centered on the Clinoid apophysis.

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“…Some authors have also made an attempt to observe a possible relationship between race and type of cleft. Many studies revealed a higher frequency of clefts among caucasian patients in relation to individuals of African descent 6,13,14,19 . A trend towards higher rates of clefts among populations of Asian descent in relation to all other races has also been found 14 .…”

Section: Introductionmentioning

confidence: 99%

Current data on the characterization of oral clefts in Brazil

et al. 2004

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ABSTRACT:This study aimed at investigating the current distribution of the several types of clefts among the patients receiving treatment at the Hospital for Rehabilitation of Craniofacial Anomalies (HRAC-USP), Bauru, Brazil, for the first time during the year 2000. A total of 803 unoperated patients with cleft lip and/or palate, with or without additional malformations, with no recognizable syndromes, who came to the HRAC-USP for enrollment for treatment during the year 2000. A predominance of complete cleft lip and palate, either unilateral or bilateral, was observed (37.1%), followed by isolated cleft palate (31.7%) and isolated cleft lip (28.4%). A discrete relationship between cleft palate and the female gender was noticed (53%), and males were more affected by the other types of clefts (around 60%). The findings revealed a predominance of complete clefts of the primary and secondary palate, the treatment of which is more complex, and whose frequency is greater in males.

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Associated Malformations in Infants With Cleft Lip and Palate: A Prospective, Population-based Study

Cited by 226 publications

References 5 publications

Management of Children With Cleft Lip and Palate: A Review Describing the Application of Multidisciplinary Team Working in This Condition Based Upon the Experiences of a Regional Cleft Lip and Palate Centre in the United Kingdom

Management of Children With Cleft Lip and Palate: A Review Describing the Application of Multidisciplinary Team Working in This Condition Based Upon the Experiences of a Regional Cleft Lip and Palate Centre in the United Kingdom

Frequency of Ponticulus Posticus, Sella Turcica Bridge and Clinoid Enlargement in Cleft Lip and Palate Peruvian Patients: A Comparative Study with Non-Cleft Patients

Current data on the characterization of oral clefts in Brazil

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