Associação de imunoestimulante com anti-helmíntico no tratamento da verminose em ovinos

Martins, Maria de Fátima; García, Mario Honrubia; Chate, Sabrina Caruso; Tavolari, Fabrízia Aparecida; Teixeira, Raffaella Bertoni Cavalcanti; Júnior, Luis Roberto Mertens; Silva, Marilene Machado; Scheibel, Monika; Abel, L.

doi:10.1590/s0103-84782012005000142

Cited by 2 publications

(2 citation statements)

References 24 publications

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“…In wellfed animals and in animals with greater resistance to worms, a reduction or elimination of nematodes may occur, thus, explaining the observation of leukogram values within the normal range (AMARANTE; SALES, 2007). Parasitized sheep treated with the immunostimulants Propionibacterium granulosum and Escherichia coli lipopolysaccharide combined with albendazole anthelmintic resulted in neutrophil mean values ranging from 8.166 to 9.640/μL (MARTINS et al, 2012). These values are higher than those obtained in the present study.…”

Section: Discussioncontrasting

confidence: 87%

Blood parameters of sheep with high infection of Haemonchus contortus and treated with “mushroom of the sun” (Agaricus blazei)

et al. 2016

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Parâmetros sanguíneos de ovinos com alta infecção porHaemonchus contortus e tratados com "cogumelo do sol" (Agaricus blazei) AbstractBlood and parasitological parameters of sheep experimentally infected with Haemonchus contortus and treated with "mushroom of the sun" (Agaricus blazei) were assessed. Lambs infected with the nematode were divided into three groups: treated with basidiocarp powder from the fungus, wormed with trichlorfon, and a control group that did not receive anthelmintic. Split-plot design analysis was performed where the treatments were defined as plots and four periods of collection were defined as subplots. Interaction between the treatments and the collection periods for the fecal egg counts per gram of feces (FEC) was observed. Treatment with "mushroom of the sun" showed anthelmintic efficacies ranging from 28.6 to 54.2%. Similar performances to weight gain were observed among the groups. A significant interaction between treatments and evaluation periods was observed for erythrocyte counts, hematocrit value, and serum concentrations of albumin and urea. The values of the mean corpuscular volume, erythrocyte distribution width, and leukocyte, neutrophil, lymphocyte, monocyte, and eosinophil counts, as well as the mean platelet volume, varied among the collection days. The administration of "mushroom of the sun" significantly reduced the FEC, did not influence on the erythrocyte count and hematocrit value, which remained within normal limits. However it increased the serum concentrations of albumin. com triclorfon e grupo controle, que não recebeu anti-helmíntico. Utilizou-se delineamento em parcelas subdivididas, sendo os tratamentos as parcelas e quatro períodos de coletas, as subparcelas. Verificouse interação dos tratamentos e dos períodos de coleta para o número de ovos por grama de fezes (OPG). O tratamento com "cogumelo do sol" apresentou eficácia anti-helmíntica variando de 28,6% a 54,2%, entretanto o desempenho foi semelhante entre os grupos. Verificou-se interação significativa dos tratamentos e os períodos avaliados para as contagens de eritrócitos, o valor do hematócrito e as concentrações séricas de albumina e ureia. Os valores do volume corpuscular médio, da amplitude de distribuição de eritrócitos, as contagens de leucócitos, neutrófilos, linfócitos, monócitos e eosinófilos, bem como o volume plaquetário médio variaram entre os dias de coleta. A administração do "cogumelo do sol" reduziu o OPG, não influenciou a contagem de eritrócitos e o valor do hematócrito, que estiveram dentro dos limites da normalidade, e aumentou significativamente as concentrações séricas de albumina. Palavras-chave: Agaricus blazei. Controle alternativo. Haemoncose. Ovinos. Perfil sanguíneo.

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Section: Discussioncontrasting

confidence: 87%

Blood parameters of sheep with high infection of Haemonchus contortus and treated with “mushroom of the sun” (Agaricus blazei)

et al. 2016

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“…Although these results did not show statistical differences, we strongly suggest the use of a combination of immunostimulants with anthelmintics in antiparasitic treatments for nematode infections. Martins et al (2012) studied a group of sheep treated with antiparasitics and another group treated with antiparasitics combined with immunostimulants and found no significant differences in the EPG values, although lower values were observed in all samples treated with the combination.…”

Section: Discussionmentioning

confidence: 97%

Combination of immunostimulants with moxidectin in the treatment of animals experimentally infected with Haemonchus contortus

Portella

Fernandes

Sangioni

et al. 2021

Semina: Ciênc. Agrár.

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Considering the importance of Haemonchus contortus infection in herds along with parasitic resistance, the goal of this study was to evaluate the influence of the administration of adjuvants alone or in combination with anthelmintics for the treatment of H. contortus, in experimentally infected sheep. Thirty sheep of the Texel breed of both genders, raised in a herd located in the subtropical region of Brazil, were used in this experiment. Experimental infection with H. contortus was performed in sheep, and the infected sheep were then separated into groups for the administration of antiparasitic and immunostimulant drugs. The results obtained from the excretion of eggs per gram of feces and the count of parasites during necropsy affirm that the use of adjuvants in combination with anthelmintics is associated with higher efficacy of treatment, lower rate of reinfection, and retardation in the development of anthelmintic drug resistance by H. contortus. Based on these results, we can conclude that the combination of anthelmintics and immunostimulants may favor potential anthelmintic treatments for H. contortus.

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Associação de imunoestimulante com anti-helmíntico no tratamento da verminose em ovinos

Cited by 2 publications

References 24 publications

Blood parameters of sheep with high infection of Haemonchus contortus and treated with “mushroom of the sun” (Agaricus blazei)

Blood parameters of sheep with high infection of Haemonchus contortus and treated with “mushroom of the sun” (Agaricus blazei)

Combination of immunostimulants with moxidectin in the treatment of animals experimentally infected with Haemonchus contortus

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