Assignment of the human cytokeratin 3 gene (KRT3) to 12q12→q13 by FISH

Abstract

We used fluorescence in situ hybridization to localize the human gene for cytokeratin 3 (KJRT3), a member of the type II subfamily of cytokeratins, within the human genome. The results show that KRT3 is located within chromosome region 12q12→q13. All human type II keratin genes mapped to date have been assigned to chromosome 12, where they are likely to be organized into one homotypic cluster.