Assessment оf the state оf compensatory resources and the dеgrее оf adaptation оf the body tо environmental conditions in full-term infants: cross-sectional study

Abstract

Aim. Assessment of the state of compensatory resources and the degree of adaptation of the body to environmental conditions in early and full-term infants in comparison with each other and with practically healthy children.
 Materials and methods. Under the supervision of 135 infants. 110 were born from mothers with a burdened somatic and obstetric-gynecological history, 41 of them were born at 3738 weeks (Group 1), 69 at 3942 weeks (Group 2). The control group (Group 3) consisted of 25 practically healthy children born to practically healthy mothers as a result of physiological pregnancies and childbirth at 3840 weeks. The children were examined in dynamics at the age of 1 (n=126), 3 (n=116), 6 (n=110), 12 (n=111) months. A comprehensive analysis of the data of anamnesis, physical examination, cardiointervalography was carried out. The following parameters were evaluated initially and in response to the tilt test: mode (М0), mode amplitude (AM0), delta x (∆Х), voltage index (IN). Nonparametric methods of statistical analysis were used.
 Results. At the age of 2 to 3 days infants born to women with a history of poor health recorded a significant decrease in the median IN1 value, respectively, in Groups 1, 2, and 3, which indicates a decrease in compensatory reserves, particularly in neonates born at 3840 weeks. At 1 month of age, Group 1 and 2 had higher median IN1 values of 804 and 746 versus 550 in Group 3, indicating the development of compensatory resource tension, particularly in children born at 3738 weeks. At 3 months of age, children in group 1 retained a compensatory tension of IN1 resources 521 versus 468 and 460 in groups 2 and 3. At 6 months of age, there is a slight decrease in compensatory IN1 reservers at 6 months of age in children from women with a history of a history of a history of a history of a disease 376 and 357 versus 400 in Group 3. At 12 months of age, children in the main groups have even more decreased compensatory resources, especially in group 1 IN1 206, 284 and 380 respectively in groups 1, 2 and 3.
 Conclusion. The decrease of functional reserve of adaptation in children of groups 1st and 2nd was facilitated by the influence burdened with somatic and obstetric-gynecological history of mothers, regardless of gestational age and subsequently the health characteristics of children themselves. The statistically significant differences found in the state of compensatory resources and the degree of adaptation of the organism to environmental conditions justify the personalized approach, which justifies a personalized approach when choosing rehabilitation measures.