The persistent challenge of youth unemployment remains a significant concern for developing economies worldwide, including Nigeria, which has a burgeoning young population. In the evolving digital age reshaping industries and labor markets, equipping the youth with relevant and in-demand skills has become crucial to address this pressing issue. Data science has emerged as a transformative domain, driving data-driven decision-making and offering immense potential for career opportunities. Against this backdrop, the present study aims to explore the promising role of data science education in empowering Nigerian youths and combating unemployment.Literature on youth unemployment in Nigeria emphasizes the need for proactive interventions to bridge the skills gap and enhance employability prospects. Data science, with its interdisciplinary nature and emphasis on analytical and technical proficiencies, provides a promising avenue for equipping the youth with in-demand skills. Recent studies underscore the positive impact of data-driven technologies on various industries, highlighting the relevance of data science skills in the current job market.A comprehensive literature review reveals that perceptions of acquiring data science skills play a pivotal role in shaping youths' interest and motivation to pursue this field. Studies in other contexts indicate that perceived benefits and career opportunities significantly influence individuals' decisions to engage in skill acquisition. Moreover, addressing barriers to skill acquisition is essential to ensure inclusivity and accessibility of data science education for all Nigerian youths. Encouragement and support from stakeholders, including educational institutions, governmental bodies, and private sectors, are vital in nurturing a data science-focused ecosystem that fosters skill development among youths. Additionally, understanding the impact of a lack of background in relevant subjects such as statistics, A B S T R A C TThis article delves into the possibilities of leveraging data science education to empower Nigerian youths and combat unemployment challenges. It delves into the perceived advantages and obstacles associated with acquiring data science skills, while also exploring the impact of promoting skill acquisition and providing practical usage opportunities on youths' perspectives toward solving unemployment. The study further delves into the significance of background knowledge in statistics, mathematics, and computer science in the process of skill acquisition. Employing quantitative analysis and validity assessments, the article aspires to furnish valuable insights for policymakers and stakeholders aiming to formulate effective programs. These programs are intended to equip Nigerian youths with the necessary skills to thrive in the job market, thereby contributing to both personal success and overall economic growth.