Assessment of voltage criteria for left ventricular hypertrophy in adult hypertensives in south-western Nigeria

Ogunlade, Oluwadare; Akintomide, Anthony Olubunmi

doi:10.1016/j.jcdr.2013.02.005

Cited by 8 publications

(12 citation statements)

References 19 publications

(21 reference statements)

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“…Furthermore, the V3 lead is closer to the LV and is probably less influenced by variations in the distance between the myocardium and the leads. However, our finding is consistent with the report of a few studies [4] [32] [37] of a better performance of Sokolow-Lyon index vs. Cornell indexes. The exact mechanism underlying the better performance of Sokolow-Lyon index is not clear and could be related to age and BMI of the studied patients as well as the modality of LVM indexation.…”

Section: Discussionsupporting

confidence: 93%

“…Among identified factors, left ventricular hypertrophy (LVH) is thought to play a central role in the development and progression of CVD [3]. LVH has been reported to be associated with cardiac arrhythmias, ischemic heart disease, congestive heart failure, and sudden death [4]. Given the prognostic importance of LVH, accurate diagnosis and appropriate management of LVH have become a major component of the care of patients with hypertension [3].…”

Section: Introductionmentioning

confidence: 99%

“…Despite the low sensitivity of available ECG indexes ranging from 7% to 35% in mild hypertension and 10% to 50% in moderate to severe hypertension [8], ECG is still in use in many parts of the world including Sub-Saharan Africa where echocardiography is not often available [9]. The most commonly used ECG indexes for the diagnosis of LVH include Sokolow-Lyon voltage, Cornell voltage and Cornell product indexes [4] [7] [10]. Given the differences of sensitivity of these different indexes, it appears thus rational to assess and compare them with echocardiography to assess their suitability for routine use for the diagnosis of LVH in hypertensive patients especially those with RKF [4] [7].…”

Section: Introductionmentioning

confidence: 99%

“…The most commonly used ECG indexes for the diagnosis of LVH include Sokolow-Lyon voltage, Cornell voltage and Cornell product indexes [4] [7] [10]. Given the differences of sensitivity of these different indexes, it appears thus rational to assess and compare them with echocardiography to assess their suitability for routine use for the diagnosis of LVH in hypertensive patients especially those with RKF [4] [7].…”

Section: Introductionmentioning

confidence: 99%

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Comparison of the Performance of Three Commonly Used Electrocardiographic Indexes for the Diagnosis of Left Ventricular Hypertrophy in Black Hypertensive Patients with Reduced Kidney Function Managed at a Tertiary Healthcare Hospital: A Post-Hoc Analysis

Lepira¹,

Mpembe²,

Mbutiwi³

et al. 2017

WJCD

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Background: Reduced kidney function in blacks is associated with an increased frequency of left ventricular hypertrophy. Given the unavailability of echocardiography in most developing countries, the diagnostic performance of current ECG indexes needs to be evaluated. Objective: To compare the diagnostic performance of 3 commonly used ECG indexes (Sokolow-Lyon, Cornell voltage and Cornell product) in black hypertensive patients. Methods: Electrocardiography and echocardiography estimated left ventricular mass of 155 consecutive hypertensive patients who participated from January 2012 to January 2013 to an echocardiographic cross-sectional study of left ventricular structure was analyzed to compare Cornell voltage and Cornell product indexes with Sokolow-Lyon voltage index as a reference. Reduced kidney function was defined as eGFR < 60 ml/min/1.730.05 m 2 . ROC curves in relation to LVH diagnosis were used to estimate the sensitivities and specificities of each index. P < 0.05 defined the level of the statistical significance. Results: The sensitivity and specificity were 43% and 85%, 23% and 77% and 26% and 77% for Sokolow-Lyon, Cornell voltage and Cornell product indexes, respectively. However, Sokolow-Lyon index (AUC; 95% CI: 0.64; 0.50 -0.78) How to cite this paper: Lepira, F.B., Mpembe, C.M.B., Mbutiwi, F.I.N., Makulo, J.R., Kayembe, P.K., Kajingulu, K.M., Kintoki, E.V. and M'buyamba-Kabangu, J.R. 106showed better performance than Cornell voltage (0.42; 0.25 -0.59) and Cornell product (0.43; 0.28 -0.59). Sokolow-Lyon index cut-point ≥ 37 mm corresponded to the highest Youden index (39.4% of sensitivity and 92.3% of specificity). Conclusion: Although the overall performance of the 3 ECG indexes versus echocardiography was low, Sokolow-Lyon index performed better than the two other indexes in diagnosing LVH.

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Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Comparison of the Performance of Three Commonly Used Electrocardiographic Indexes for the Diagnosis of Left Ventricular Hypertrophy in Black Hypertensive Patients with Reduced Kidney Function Managed at a Tertiary Healthcare Hospital: A Post-Hoc Analysis

Lepira¹,

Mpembe²,

Mbutiwi³

et al. 2017

WJCD

View full text Add to dashboard Cite

show abstract

“…Our research focuses on healthy individuals and brings findings about differentiation between normal and pathological means in young healthy sedentary males. It contributes to previous scientific findings and shows that voltage criteria do little to reflect left ventricular mass [1,21]. On the other hand, we found that false positive meanings of Sokolow-Lyon Product prevail in 30 % of healthy male subjects, however, its ability to reflect LVM is the highest and statistically significant among all criteria under investigation in subjects with normal BMI (< 25).…”

Section: Discussionsupporting

confidence: 74%