Assessment of Vitamin D Status and Response to Vitamin D3 in Obese and Non-Obese Children and Adults

Abstract

Due to its great prevalence and harmful consequences on health, obesity appears to be a serious problem in today's society. Studies have connected obesity with lower blood calcifediol concentrations. Examining the blood vitamin D levels among overweight and non-obese adults as well as adolescents was the goal of the current study, as well as compare how they responded to the similar oral vitamin D3 treatment. The blood vitamin D levels of a small number of obese children and adults and some obese individuals were compared in a non-randomized clinical study. 1 pearl of vitamin D3 (50 000 Iu) was given to those with a blood vitamin D status of thirty milligrams per milliliter (74 occurrences) every week for six weeks. Two weeks after starting therapy, serum vitamin D levels were tested once again. At baseline, individuals with obesity had a frequency of low Vit D level of 42/44 (95.5%) compared to 31/46 (66.6%) of patients with non- obesity (p 0.002). The aforementioned percentages were reduced to 24/43 (55.8%) and 1/30 (3.3%), respectively, following therapy for these individuals (p 0.001). Our investigation showed that patients, especially those who were obese, frequently had vitamin D deficiencies. Moreover, the obese group shows a modest therapeutic response.