The aim of the article was to conduct an experimental study and provide evidence for systemic rehabilitation of student youth with post-traumatic stress disorder (PTSD). Psychodiagnostic methods that are valid and reliable with standard test forms were used. It was stated that psychological protective mechanisms such as displacement, regression, substitution, compensation, and reactive formation were more active in psychological youth with PTSD (n=112). Assimilation (n=38; 33.93%), accommodation (n=48; 42.86%), and disharmonious (n=26; 23.21%) disorders were identified. A comparison of the control and experimental groups was carried out. A cluster structural model of respondents’ PTSD types was constructed. Respondents with a high level of PTSD manifestations were shown to have excessive internal tension, dysphoria, explosiveness, and a low level of integration with the environment. It was established that the proposed systemic rehabilitation is an essential component of working with the affected contingent. It was generalized that the application of experimental results from the study of health technologies operationalizes the educational process’s work with students who have experienced post-traumatic stress disorder.