Assessment of Transfusion Needs in Pediatric Hematology-oncology

Lemssahli, Ilham; Hajjout, K.; Benajiba, M.; Belmekki, Abdelkader

doi:10.31080/aspe.2021.04.0350

Cited by 3 publications

(3 citation statements)

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“…where RBC prevailed and, with those of Kracalik et al [26], where apheresis predominated, unlike those reported by Freitas et al [14], Lemssahli et al [23] and Pedrosa et al [24], who associated it mainly with platelets. This peculiarity is because both erythrocytes and platelet concentrates can contain leukocytes and proinflammatory cytokines that trigger reactions; as we observed, most transfusions were performed with RBCs and apheresis (they contain platelets).…”

Section: Transfusionsmentioning

confidence: 76%

Características transfusionales y hemovigilancia de los pacientes pediátricos con cáncer

Urdiales Valarezo,

Guerrero Quiroz

2023

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Introducción: La terapia transfusional no está libre de riesgos, siendo los pacientes hemato- oncológicos los mayores transfundidos, por ello la necesidad de la hemovigilancia. El objetivo del presente estudio fue identificar las características transfusionales y la hemovigilancia de los pacientes pediátricos con cáncer en el Instituto SOLCA-Cuenca, enero-diciembre 2021. Método: Se realizó un estudio descriptivo con todos los pacientes menores de 18 años que requirieron transfusiones y todas las hemotransfusiones realizadas en SOLCA-Cuenca 2021. Los datos fueron recolectados en un formulario previamente validado y se analizaron en el programa SPSS v25.0, presentándose como frecuencias, porcentajes, media y desviación estándar. Resultados: Se estudiaron 73 pacientes y 620 transfusiones, predominando: adolescentes (45.2 %), de sexo masculino (63 %), mestizos (98.6 %), urbanos (76.7%), grupo ORH+ (83.5 %). Con leucemia linfoblástica aguda células B (49.3 %) y quimioterapia de inducción (41.1 %). El 58.9 % tenían antecedente transfusional y 4.1 % reacción previa (urticaria). La media transfusional por paciente fue 8,49 y, 7,1% fueron premedicadas con esteroides; se transfundieron principalmente concentrados eritrocitarios (49%) por anemia (95.4 %) a 9,32ml/kg (media) en 121 a 180 minutos (56.9 %). Del 3.1 % de reacciones evidenciadas, el 100% fueron inmediatas, no infecciosas (urticaria 84.2 %), definitivas y se trataron con medicamentos (84.2 % esteroide); el 79 % de reacciones fueron leves; fueron secundarias a concentrados eritrocitarios (47.4 %), aféresis (47.4 %) y; evidenciadas en pacientes con leucemia linfoblástica aguda células B (31.5 %). Conclusiones: Los pacientes con leucemia linfoblástica aguda células B requirieron más transfusiones sanguíneas, principalmente concentrados eritrocitarios; mientras las reacciones transfusionales se asociaron frecuentemente a concentrados eritrocitarios y aféresis.

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Section: Transfusionsmentioning

confidence: 76%

Características transfusionales y hemovigilancia de los pacientes pediátricos con cáncer

Urdiales Valarezo,

Guerrero Quiroz

2023

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“…For adverse reaction reports, the incidence recorded did not exceed 1.31/1000 LBPs, compared to the incidence reported in France. This low rate is due to underreporting and not decreased RARs [29].…”

Section: Traceability and Hemovigilancementioning

confidence: 89%

Assessment of transfusion practices in pediatrics: A case report

Ilham¹,

Abdelkader²

2022

Int J Blood Transfus Immunohematol

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Introduction: Pediatric patients should not be exposed to blood components and products unnecessarily. Transfusion-related risks are always present, both those we know and those that remain to be discovered. It is essential to follow good transfusion practice (GTP) procedures; although they can sometimes be quite prescriptive, evidence shows that when we ignore guidelines, errors can occur. Case Report: We report the case of a 7-month-old infant who underwent surgery for megacolon and received emergency transfusions. The death of the infant post-surgery prompted a hemovigilance investigation to determine the imputability of the transfusion. Conclusion: The investigation revealed deficiencies in the patientandrsquo;s transfusion management, some of which were critical. This indicates that nurses have a considerable knowledge deficit in blood transfusion; however, the infantandrsquo;s death was not attributable to transfusion and was due to post-surgical complications.

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“…Member States of ECOWAS must take all necessary measures to ensure 100% traceability of all blood and blood components collected, tested, processed, stored, released and transfused across the sub region from vein to vein from the blood donor to the recipient. Effective haemovigilance implementation across the West African sub region will require collaboration, effective communication and cooperation between the National Blood Transfusion Centre and the Health establishment on one hand as well as among all the healthcare professionals involved in blood transfusion service delivery [211]. Haemovigilance practice was observed to be lacking in previous studies on transfusion practice in Africa [212].…”

Section: Haemovigilance Implementation In the West African Sub-regionmentioning

confidence: 99%

Optimizing Blood Transfusion Service Delivery across the West African Sub-Region

Erhabor,

O. Akpotuzor,

Yaw Afriyie

et al. 2023

Thalassemia Syndromes - New Insights and Transfusion Modalities

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The sub-continent of West Africa is made up of 16 countries: Benin, Burkina Faso, Cape Verde, Ghana, Guinea, Guinea-Bissau, Ivory Coast, Liberia, Mali, Mauritania, Niger, Nigeria, Senegal, Sierra Leone, The Gambia and Togo. As of 2018, the population of the sub-continent was estimated at about 381 million. The main challenge associated with blood transfusion service delivery across the sub-region concerns adequacy and safety. In this chapter, we highlighted the challenges associated with the delivery of a quality blood transfusion service in countries in the sub-region including: implementation of component therapy rather than whole blood transfusion, effective cold chain management of blood and blood products, alloimmunization prevention, implementation of column agglutination and automation rather than the convention manual tube method in blood transfusion testing, effective management of major haemorrhage, optimization of screening for transfusion transmissible infections, optimizing blood donation, implementation of universal leucodepletion of blood and blood products, effective management of transfusion-dependent patients, pre-operative planning and management of surgical patients, management of Rhesus D negative pregnancy and women with clinically significant alloantibodies, implementation of haemovigilance system, implementation of alternatives to allogenic blood, availability and use of specialized blood products, optimizing safe blood donation, enhancing blood transfusion safety, operating a quality management system-based blood transfusion service and implementation of non-invasive cell-free foetal DNA testing. There is the urgent need for the implementation of evidence-based best practices in blood transfusion service delivery across the sub-region to allow for excellent, safe, adequate and timely blood transfusion service delivery across the sub-region.

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Assessment of Transfusion Needs in Pediatric Hematology-oncology

Cited by 3 publications

References 0 publications

Características transfusionales y hemovigilancia de los pacientes pediátricos con cáncer

Características transfusionales y hemovigilancia de los pacientes pediátricos con cáncer

Assessment of transfusion practices in pediatrics: A case report

Optimizing Blood Transfusion Service Delivery across the West African Sub-Region

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