Assessment of the strain in small sodium chlorate crystals and its relation to growth rate dispersion

Ristić, R. I.; Sherwood, J. N.; Wojciechowski, Krzysztof

doi:10.1016/0022-0248(88)90382-x

Cited by 101 publications

(61 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This phenomenon, termed growth rate dispersion, can be a consequence of differences in dislocation structure between equivalent crystallographic faces of the crystal (CHERNOV et al 1986), or the degree of crystal lattice strain (MITROVIC 1989, ZACHER, MERSMANN 1995, RISTIC et al 1988, MITROVIC et al 1990, VAN DER HEIJDEN, VAN DER EERDEN 1992). Earlier, growth rate dispersions were described by different distributions with only one maximum.…”

Section: Introductionmentioning

confidence: 99%

Improvement of Initial Conditions of the Crystal Growth by Dissolution and Refaceting

Žekić

Mitrovic

2002

Cryst. Res. Technol.

View full text Add to dashboard Cite

The influence of significant dissolution and refaceting of KDP and Rochelle salt crystals on their further growth is studied. It is shown that the crystal growth rate ‐ initial crystal size dependence is better defined for growth after refaceting. Initial conditions for growth of individual crystals after refaceting are better defined, than in the case of classical seed nucleation. By dissolution and refaceting, it is easy to provide the same initial conditions for crystal growth in each of several experiments, preformed under the same macroscopic external conditions.

show abstract

Section: Introductionmentioning

confidence: 99%

Improvement of Initial Conditions of the Crystal Growth by Dissolution and Refaceting

Žekić

Mitrovic

2002

Cryst. Res. Technol.

View full text Add to dashboard Cite

show abstract

“…Similar observations of growth rate increase with crystal size abound in the mass crystallization literature (Ulrich & Kruse, 1990;Tulke & Offermann 1990;Zacher & Mersmann, 1995), where this phenomenon is studied to reduce unwanted growth rate dispersion. In investigation of individual crystals of sodium chlorate (Ristic, Sherwood & Wojciechowski, 1988, Rochelle salt (Mitrovic, 1994) and ammonium sulfate ((3 Meandra, Kramer & van Rosmalen, 1995), the lower growth rates of smaller crystals were correlated to their topographically determined higher strain densities. These were envisaged, in turn, to increase the solubility of the smaller crystals and, hence, to decrease the supersaturation and growth rate.…”

Section: Core Lattice Strain and Growth Ratementioning

confidence: 99%

Repartitioning of NaCl and Protein Impurities in Lysozyme Crystallization

Vekilov

Monaco²,

Thomas³

et al. 1996

Acta Cryst D

View full text Add to dashboard Cite

Nonuniform precipitant and impurity incorporation in protein crystals can cause lattice strain and, thus, possibly decrease the X-ray diffraction resolution. To address this issue, a series of crystallization experiments were carried out, in which initial supersaturation, NaCI concentration, protein purity level and crystallized fraction were varied. Lysozyme and protein impurities, as well as sodium and chloride were independently determined in the initial solution, supernatant and crystals. The segregation coefficients for Na ÷ and CIwere found to be independent of supersaturation and NaCI concentration, and decreased with crystallized fraction/crystal size. Numerical evaluation of the extensive body of data, based on a nucleation-growthrepartitioning model, suggests a core of ~-,40p, m in which salt is incorporated in much greater concentrations than during later growth. Small crystals containing higher amounts of incorporated NaCI also had higher protein impurity contents. This suggests that the excess salt is associated with the protein impurities in the core. X-ray topography revealed strain fields in the center of the crystals comparable in size to the inferred core. The growth rates of crystals smaller than 30-40 ~tm in size were consistently 1.5-2 times lower than those of larger crystals, presumably due to higher chemical potentials in the core.

show abstract

“…From the experimental determination of the solubility data for ibuprofen in solvents, the enthalpy and entropy of dissolution were calculated using the van't Hoff equation: (15) where X is the mole fraction of solute in solution and ∆H diss and ∆S diss are the enthalpy and entropy of dissolution, respectively;…”

Section: Data Analysis 341 Solubilitymentioning

confidence: 99%

“…Linking these two, quite distinctive, sets of measurements is a challenge mindful of the quite different hydrodynamic environments involved. For example in the former case whilst measurements are made on the individual growth faces, the influence imposed either by the hydrodynamic environment associated with the measurements or by the selection of the specific seeds [15] for the studies is not really defined. Similarity, in the latter case, it is hard to extract out the kinetics associated with the growth of the individual habit faces.…”

Section: Introductionmentioning

confidence: 99%

Precision measurement of the growth rate and mechanism of ibuprofen {001} and {011} as a function of crystallization environment

et al. 2014

View full text Add to dashboard Cite

Article:Nguyen, TTH, Hammond, RB, Roberts, KJ et al. (2 more authors) (2014) Precision measurement of the growth rate and mechanism of ibuprofen {001} and {011} as a function of crystallization environment. CrystEngComm, 16 (21). 4568 -4586. ISSN 1466-8033 https://doi.org/10.1039/c4ce00097h eprints@whiterose.ac.uk https://eprints.whiterose.ac.uk/ Reuse Unless indicated otherwise, fulltext items are protected by copyright with all rights reserved. The copyright exception in section 29 of the Copyright, Designs and Patents Act 1988 allows the making of a single copy solely for the purpose of non-commercial research or private study within the limits of fair dealing. The publisher or other rights-holder may allow further reproduction and re-use of this version -refer to the White Rose Research Online record for this item. Where records identify the publisher as the copyright holder, users can verify any specific terms of use on the publisher's website. TakedownIf you consider content in White Rose Research Online to be in breach of UK law, please notify us by emailing eprints@whiterose.ac.uk including the URL of the record and the reason for the withdrawal request. acetonitrile. The crystal growth rates of the {001} and {011} faces of spontaneously nucleated crystals are precisely measured in-situ using optical microscopy revealing that their respective growth rates increase with increasing supersaturation to different extents, depending on the solvent type, with concomitant impact on the crystal habit. The measured aspect ratios, as a function of supersaturation, are generally higher at the 15 mL than the 0.5 mL scale size.Analysis of the growth rates versus supersaturation is consistent with a 2-D surface nucleation (Birth and Spread) model for both faces and at both scale sizes. The growth rates of the {001} and {011} faces exhibit much less growth rate dispersion when compared to literature data for a stirred batch crystallizer. 2The data is rationalized by examining the surface chemistry of the growing faces revealing, e.g. that polar protic solvents inhibit the growth rate of faces containing available binding sites for hydrogen bonding formation, such as carboxylic acid groups.

show abstract

Assessment of the strain in small sodium chlorate crystals and its relation to growth rate dispersion

Cited by 101 publications

References 8 publications

Improvement of Initial Conditions of the Crystal Growth by Dissolution and Refaceting

Improvement of Initial Conditions of the Crystal Growth by Dissolution and Refaceting

Repartitioning of NaCl and Protein Impurities in Lysozyme Crystallization

Precision measurement of the growth rate and mechanism of ibuprofen {001} and {011} as a function of crystallization environment

Contact Info

Product

Resources

About