Assessment of the regional myocardial deformation changes and viability in anterior acute myocardial infarction patients by strain and strain rate imaging

Abstract

Assessment of the regional myocardial deformation changes and viability in anterior acute myocardial infarction patients by strain and strain rate imagingAnteriyor akut miyokart enfarktüslü hastalarda bölgesel miyokardiyal deformasyon değişiklikleri ve canlılığın gerilme ve gerilme oranı görüntülemesi ile değerlendirilmesi Original Investigation Özgün Araşt›rma 479Address ABSTRACTObjective: To prospectively evaluate the regional myocardial deformation changes and viability in anterior acute myocardial infarction (AMI) patients before and after primary coronary intervention (PCI) by strain (S)/strain rate (Sr) imaging. Methods: Twenty-one patients presented during the first six hours of an anterior AMI and twenty controls were included in this study. Echocardiographic recordings were obtained from the apical/parasternal images just before PCI, one week and one month after PCI. The S/Sr and velocity (V) were measured from the basal mid and apical segments of the walls supplied by the left anterior descending artery. Myocardial perfusion scintigraphy was performed in the 1 st month after PCI. Mann-Whitney U and Wilcoxon tests were used for statistical analysis.Results: Acute myocardial infarction resulted in the reduction of deformation indices (S/Sr/V) in all segments. Deformation indices were increased after successful PCI. The S/Sr values of the normal and ischemic segments after PCI were higher compared to the baseline (ischemic Sr:-1.3±0.3 vs. -1.1±0.3, p=0.04). No difference was noted in the S/Sr values of the necrotic segments during the first week (Sr:-1.1±0.3 vs. -1.0±0.3, p=0.054). For V measurements, no difference was observed between the viability types at the follow-up measurements (p>0.05). Conclusion:The remedial effect of PCI on the deformation values was observed in the first week and continued during the first month. In the early reperfusion period, S/Sr indices have the potential to differentiate necrotic tissue from other viability types. Strain/Strain rate imaging can be used for determination of myocardial deformation changes and parameters of viability. However, V values were insufficient.

Left ventricular remodeling assessment in patients with anterior acute myocardial infarction treated with successful primary percutaneous coronary intervention: an observational study

“…In the study of Aksakal et al (26), as in current study, it was indicated that, after successful PCI, important left ventricular echocardiographic parameters were recovered. We planned to conduct our study via (with) conventional echocardiography method, since tissue Doppler and strain echocardiography was not available in our hospital in that period of time.…”

“…On the other hand, tissue Doppler and strain rate echocardiography have been used for determining the left ventricular contractility and vitality and its superiority to conventional echocardiography methods was shown (25,26). In the study of Aksakal et al (26), as in current study, it was indicated that, after successful PCI, important left ventricular echocardiographic parameters were recovered.…”

“…We planned to conduct our study via (with) conventional echocardiography method, since tissue Doppler and strain echocardiography was not available in our hospital in that period of time. Aksakal et al (26) have reported that strain/strain rate imaging have been used for determination of myocardial deformation changes and parameters of viability and compared with Tl-201 imaging.…”

The effect of incremental endurance exercise training on left ventricular mechanics: a prospective observational deformation imaging study

“…Strain echocardiography has been used in the quantitative assessment of LV contractile function in many cardiovascular diseases (9)(10)(11)(12). Initially myocardial deformation was assessed by tissue Doppler imaging derived S. But the most important limitation of this technique is angle-dependent and deformation can only be assessed longitudinally (8,(13)(14)(15).…”

Assessment of agreement between transthoracic and transesophageal echocardiography techniques for left ventricular longitudinal deformation imaging and conventional Doppler parameters estimation: a cross-sectional study

“…All data were acquired at a high frame rate of >120 frame/s. Utmost attention was paid to keep the region of interest at the center of the ultrasound sector to ensure an alignment as close to 0 as possible to long-axis motion (4)(5)(6)(7)15). In all the samples studied, we always selected three consecutive cardiac cycles, which were used for subsequent analysis.…”