AssesSment of the left atrial appendage morphoLogy in patients aAfter ischaeMic Stroke — the ASSAM study protocol

Michałowska, Ilona; Kowalik, Ilona; Kułakowski, Piotr

doi:10.5603/kp.a2017.0077

Cited by 4 publications

(3 citation statements)

References 12 publications

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“…The study design was previously described. 2 Briefly, this prospective observational study included 74 consecutive randomly chosen patients after ischemic stroke, with AF, who were hospitalized in the neurological rehabilitation department after experiencing ischemic stroke between 2014 and 2016. The control group consisted of 83 randomly chosen subjects with AF, without a history of TE, scheduled for AF ablation in the cardiological ward (Fig.…”

Section: Methodsmentioning

confidence: 99%

Association of Left Atrial Sphericity with Risk of Stroke in Patients with Atrial Fibrillation. Sub-Analysis of the ASSAM Study

Dudzińska-Szczerba

Zalewska

Niemiro

et al. 2021

Cardiovasc Eng Tech

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Purpose The study was designed to evaluate the value of left atrial (LA) sphericity (LASP) in the identification of patients with atrial fibrillation (AF) who had prior ischemic stroke. The secondary aim was to investigate the possibility of improving stroke risk assessment based on six geometrical variables of LA. Methods This prospective observational study involved 157 patients: 74 in the stroke group and 83 in the control. All patients had cardiac computed tomography (CT) performed to analyze LA volume and dimensions. LASP and the discriminant function of six geometrical measurements were calculated. Results Multivariate logistic regression analysis showed a significant association of stroke with and gender, diabetes, CHA2DS2-VASc score, LA anteroposterior diameter, and LA sphericity. Patients with prior stroke had lower LASP than those without (66.6 ± 10.3% vs. 70.5 ± 7%; p = 0.0062). The most accurate identification of patients with a history of ischemic stroke was achieved by using a function of six geometrical measurements, the sphericity and volume coefficient. The C-statistic was higher for the above discriminant function (0.7273) than for LASP (0.3974). The addition of the discriminant function to the CHA2DS2-VASc score increased the performance of the risk score alone. Conclusion LASP is associated with prior stroke in AF patients. The proposed new formula for identification of AF patients who are at risk of stroke, based on geometrical measurements of LA, is superior to the basic LASP in identification of AF patients with a history of stroke.

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Section: Methodsmentioning

confidence: 99%

Association of Left Atrial Sphericity with Risk of Stroke in Patients with Atrial Fibrillation. Sub-Analysis of the ASSAM Study

Dudzińska-Szczerba

Zalewska

Niemiro

et al. 2021

Cardiovasc Eng Tech

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“…The detailed study design and patient's inclusion criteria were published elsewhere. 12 All patients selected for the ASSAM study had to have a confirmation of AF before stroke event. It was confirmed in the selection phase based on electrocardiogram (ECG) or Holter monitoring.…”

Section: Methodsmentioning

confidence: 99%

“…The study was a subanalysis of the ASSAM study. The detailed study design and patient’s inclusion criteria were published elsewhere 12. All patients selected for the ASSAM study had to have a confirmation of AF before stroke event.…”

Section: Methodsmentioning

confidence: 99%

Left Atrial Septal Pouch—Is it Really a New Risk Factor for Ischemic Stroke?

Michałowska¹,

Dudzińska

Kowalik

et al. 2021

Journal of Thoracic Imaging

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Purpose: The atrial septal pouch is an anatomic variant of the interatrial septum caused by incomplete fusion of the septum primum and secundum. It is debatable whether coexistence of septal pouch and atrial fibrillation (AF) increases the risk of stroke. Thus, the aim of the study was to evaluate the coexistence of left atrial septal pouch (LASP) and AF in patients with a history of stroke in comparison with those without an earlier history of stroke. Materials and Methods: We analyzed 145 patients with AF (68 in the study group, 77 in the control group). The study group consisted of patients with previous stroke and AF; control group consisted of patients scheduled for AF ablation. All patients underwent computed tomography with the assessment of atrial septum morphology and presence of LASP. The study was a subanalysis of the ASSAM (AssesSment of the left atrial appendage morphoLogy in patients aAfter ischaeMic Stroke) study. Results: The prevalence of LASP in the entire group was 38.6%. There were no significant differences in the prevalence of LASP between the study and control groups (33.8% vs. 42.9%, P=0.265). Mean longitudinal and transverse dimensions of LASP were 9.34±3.27 and 2.4±0.6 mm, respectively, and there was no significant difference between the study and controls. Patients from the stroke group were older (P<0.0001), had a higher CHA2DS2-VASc score (5.41±1.93 vs. 1.62±1.46, P<0.0001) compared with controls. Conclusions: Presence of LASP is not more prevalent in patients with a history of stroke. Additional information on the presence of LASP do not improve accuracy of risk stratification for stroke in patients with AF.

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Prothrombotic State in Atrial Fibrillation Patients With One Additional Risk Factor of the CHA2DS2-VASc Score (Beyond Sex)

Głowicki¹,

Matusik

Plens

et al. 2019

Canadian Journal of Cardiology

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AssesSment of the left atrial appendage morphoLogy in patients aAfter ischaeMic Stroke — the ASSAM study protocol

Cited by 4 publications

References 12 publications

Association of Left Atrial Sphericity with Risk of Stroke in Patients with Atrial Fibrillation. Sub-Analysis of the ASSAM Study

Association of Left Atrial Sphericity with Risk of Stroke in Patients with Atrial Fibrillation. Sub-Analysis of the ASSAM Study

Left Atrial Septal Pouch—Is it Really a New Risk Factor for Ischemic Stroke?

Prothrombotic State in Atrial Fibrillation Patients With One Additional Risk Factor of the CHA2DS2-VASc Score (Beyond Sex)

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