Assessment of the efficacy of a topical combination of fipronil-permethrin (Frontline Tri-Act®/Frontect®) against egg laying and adult emergence of the cat flea (Ctenocephalides felis) in dogs

Beugnet, Frédéric; Halos, Lénaïg; Lebon, Wilfried; Liebenberg, Julian

doi:10.1051/parasite/2016068

Cited by 6 publications

(1 citation statement)

References 20 publications

(36 reference statements)

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“…A fipronil/permethrin combination provided 95.3% kill against adult fleas 36 h after treatment and 100% after flea challenges up to 8 weeks. The combination prevented flea egg laying from treated pets for at least 57 days [ 314 ]. The combination of fipronil/permethrin provided >95% kill of C. felis in 2 h for up to 14 days [ 315 ].…”

Section: Pest Managementmentioning

confidence: 99%

The Biology and Ecology of Cat Fleas and Advancements in Their Pest Management: A Review

Rust

2017

Insects

113

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The cat flea Ctenocephalides felis felis (Bouché) is the most important ectoparasite of domestic cats and dogs worldwide. It has been two decades since the last comprehensive review concerning the biology and ecology of C. f. felis and its management. Since then there have been major advances in our understanding of the diseases associated with C. f. felis and their implications for humans and their pets. Two rickettsial diseases, flea-borne spotted fever and murine typhus, have been identified in domestic animal populations and cat fleas. Cat fleas are the primary vector of Bartonella henselae (cat scratch fever) with the spread of the bacteria when flea feces are scratched in to bites or wounds. Flea allergic dermatitis (FAD) common in dogs and cats has been successfully treated and tapeworm infestations prevented with a number of new products being used to control fleas. There has been a continuous development of new products with novel chemistries that have focused on increased convenience and the control of fleas and other arthropod ectoparasites. The possibility of feral animals serving as potential reservoirs for flea infestations has taken on additional importance because of the lack of effective environmental controls in recent years. Physiological insecticide resistance in C. f. felis continues to be of concern, especially because pyrethroid resistance now appears to be more widespread. In spite of their broad use since 1994, there is little evidence that resistance has developed to many of the on-animal or oral treatments such as fipronil, imidacloprid or lufenuron. Reports of the perceived lack of performance of some of the new on-animal therapies have been attributed to compliance issues and their misuse. Consequentially, there is a continuing need for consumer awareness of products registered for cats and dogs and their safety.

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Section: Pest Managementmentioning

confidence: 99%

The Biology and Ecology of Cat Fleas and Advancements in Their Pest Management: A Review

Rust

2017

Insects

113

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Efficacy of topical administration of prallethrin-permethrin-piperonyl butoxide (Bronco® Equine Fly Spray) for the treatment and control of flies and other nuisance insects of horses

Genchi,

Kramer,

Valentini

et al. 2023

Parasitol Res

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Numerous biting and nuisance insects are a noted cause of discomfort and stress to horses. Pyrethrins and pyrethroids have been used for many years in numerous formulations for the control of insect pests in animals, humans and environment. There are, however, few studies reporting their field efficacy in horses. The aim of the present study was to evaluate the repellent activity of a spray formulation based on prallethrin and permethrin synergized with piperonyl butoxide (BRONCO® Equine Fly Spray, Farnam Companies, Inc., USA) against annoying and harmful insects for horses in field conditions. Nine horses of mixed breed were divided into 2 groups (treatment and control). Pre-treatment insect counts were compared to daily counts for 4 days post-treatment (pt). One minute after the administration of the product (day 0), all the horses were negative for the presence of insects. All counts up to the 6-h pt check remained negative for Hippobosca equina, tabanid flies and Simulium spp., showing 100% efficacy. This remained above 90% throughout the study. For the H. equina, the repellent efficacy remained > 99.7% for all 4 days pt, for tabanid flies > 93.3% and for Simulium spp. > 97.4%. The efficacy against Musca spp. decreased from 82.2% at day 0 to 62.2% at day 3. Treatment was well-tolerated. In conclusion, despite the low number of tested horses, Bronco® has demonstrated high insecticide and repellent efficacy and a good persistence, maintained for up to 4 days post-treatment, against the most common species of insects harmful for horses.

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CPD article: An updated review of the indications and adverse drug events associated with the ectoparasiticides used in small animal practice

Copland¹,

Elsheikha

2020

Companion Animal

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The global burden of ectoparasitic infestations is exacerbated by the lack of licensed vaccines, meaning safe and effective ectoparasiticide drugs are vital to their prevention and treatment. However, adverse clinical consequences of treatments for ectoparasites affect thousands of cats and dogs in the UK each year. The unpredictable outcomes of these treatments in some animals can be associated with undesirable consequences and there is a lack of knowledge surrounding their use. This article discusses indications of the major classes of ectoparasiticides used in small animal practice and highlights the types of adverse drug reactions associated with the parasiticides used to treat ectoparasite infestations in dogs and cats. Overall, the incidence of adverse drug events reported in relation to ectoparasiticide use, compared to the total doses administered globally, is small. The potential consequences for animal and human health of not using ectoparasiticides is likely to be more serious than the current rate of adverse drug reactions being reported. The benefits of protection from ectoparasite infestations will therefore outweigh the potential consequences of adverse events associated with such treatment.

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Assessment of the efficacy of a topical combination of fipronil-permethrin (Frontline Tri-Act^®/Frontect^®) against egg laying and adult emergence of the cat flea (Ctenocephalides felis) in dogs

Cited by 6 publications

References 20 publications

The Biology and Ecology of Cat Fleas and Advancements in Their Pest Management: A Review

The Biology and Ecology of Cat Fleas and Advancements in Their Pest Management: A Review

Efficacy of topical administration of prallethrin-permethrin-piperonyl butoxide (Bronco® Equine Fly Spray) for the treatment and control of flies and other nuisance insects of horses

CPD article: An updated review of the indications and adverse drug events associated with the ectoparasiticides used in small animal practice

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