Assessment of the effectiveness of platelet rich fibrin in the treatment of Schneiderian membrane perforation

Abstract

PRF can be considered as an alternative material for repairing sinus perforations because it is fully autogenous and easy manipulated.

Evaluation of L‐PRF combined with deproteinized bovine bone mineral for early implant placement after maxillary sinus augmentation: A randomized clinical trial

“…Importantly, the maturation of this type of material may take up to 8 months before implants can be safely placed in maxillary sinus, which might be considered a disadvantage of this material. To mitigate this shortcoming, the addition of growth factors, particularly L‐PRF, to the graft material has been suggested as an alternative approach to increase bone formation, enhance implant stability, favor osseointegration, and accelerate tissue maturation and healing …”

“…To mitigate this shortcoming, the addition of growth factors, particularly L-PRF, to the graft material has been suggested as an alternative approach to increase bone formation, enhance implant stability, favor osseointegration, and accelerate tissue maturation and healing. 1,18,21,22,[28][29][30]34,35,44,45,[47][48][49][50][51][52] CBCT is considered a reliable technique for the 3D visualization of graft volume changes after sinus augmentation. In this study, we performed three different CBCTs at different time points: immediately after the bone graft, and after 4 and 8 months of healing.…”

“…Leukocyte and platelet‐rich fibrin (L‐PRF), first described by Dohan and colleagues is an autogenous biomaterial containing several growth factors . L‐PRF, a second‐generation of platelet concentrates, is basically made of concentrated autologous platelets as well as leukocytes and cytokines . It has been demonstrated that L‐PRF activates the vascular system by promoting angiogenesis, and also by releasing several growth factors involved in soft and hard tissue healing .…”

“…1,18,19,25 L-PRF, a second-generation of platelet concentrates, is basically made of concentrated autologous platelets as well as leukocytes and cytokines. 34 It has been demonstrated that L-PRF activates the vascular system by promoting angiogenesis, and also by releasing several growth factors involved in soft and hard tissue healing. 30,35 Additionally, previous studies demonstrated that L-PRF is capable of inducing bone regeneration 22,36 and fibroblast proliferation, 37 thus improving and accelerating tissue healing, 35 and enhancing implant stability.…”

Platelet‐rich fibrin and collagen membrane in the preservation of the alveolar bone: Feasibility of the elemental inorganic composition and scanning electron microscopy analysis

“…PRF is a second‐generation platelet concentrate developed by Choukroun et al () in France. This biomaterial is autologous in clinical applications (Canellas, Ritto, & Medeiros, ; Du et al, ; Öncü & Kaymaz, ) and is produced from immediate blood centrifugation without the addition of an anticoagulant or gelling agent (Al‐Hamed, Tawfik, Abdelfadil, & Al‐Saleh, ; Canellas et al, ; Isobe et al, ).…”