2009
DOI: 10.1590/s0102-695x2009000500003
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Assessment of the effect of Bacopa monnieri (L.) Wettst. extract on the labeling of blood elements with technetium-99m and on the morphology of red blood cells

Abstract: RESUMO: "Avaliação do efeito do extrato de Bacopa monnieri (L.) Wettst. na marcação de elementos sanguíneos com tecnécio-99m e na morfologia de células vermelhas do sangue." Bacopa monnieri (L.) Wettst. (BM), uma planta tradicional da medicina ayurvédica, é usada por séculos para problemas de memória, antiinflamatória, antitérmica, sedativa e como agente anti-epiléptico. O extrato BM têm sido extensivamente investigada por diversos autores por seus efeitos neurofarmacológicas. Na medicina nuclear, os glóbulos … Show more

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Cited by 7 publications
(8 citation statements)
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References 36 publications
(41 reference statements)
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“…Data have demonstrated the effects of synthetic and natural drugs on this radiolabeling process (Mousinho et al, 2008;Holanda et al, 2009;Bustani et al, 2009;Rocha et al, 2009;De et al, 2009;Cekic et al, 2011;Souza et al, 2011). In consequence, the labeling of blood constituents with 99m Tc has been used as an in vitro assay to screening effects of synthetic or natural products that could have actions related to the band-3 and calcium channels or antioxidant/oxidant properties.…”
Section: +2mentioning
confidence: 99%
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“…Data have demonstrated the effects of synthetic and natural drugs on this radiolabeling process (Mousinho et al, 2008;Holanda et al, 2009;Bustani et al, 2009;Rocha et al, 2009;De et al, 2009;Cekic et al, 2011;Souza et al, 2011). In consequence, the labeling of blood constituents with 99m Tc has been used as an in vitro assay to screening effects of synthetic or natural products that could have actions related to the band-3 and calcium channels or antioxidant/oxidant properties.…”
Section: +2mentioning
confidence: 99%
“…In consequence, the labeling of blood constituents with 99m Tc has been used as an in vitro assay to screening effects of synthetic or natural products that could have actions related to the band-3 and calcium channels or antioxidant/oxidant properties. Moreover, qualitative and quantitative morphological analysis of RBC has been used as a method to evaluate if the effects of drugs on this radiolabeling process could be related to changes on shape of RBC (Rocha et al, 2009;De et al, 2009).…”
Section: +2mentioning
confidence: 99%
“…Assays using radionuclides have been utilized successfully in various investigations related with extracts of medicinal formulas [15] or isolated medicinal plant [16].…”
mentioning
confidence: 99%
“…Moreover, 99m Tc has been an important tool in various experimental models [16,[19][20][21][22][23][24][25]. Tc-Red blood cells (RBC) are used to get images of the cardiovascular system and, the spleen, on the detection and localisation of gastrointestinal hemorrhages and on the measurement of RBC [26][27][28].…”
mentioning
confidence: 99%
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