Assessment of the Changes in Health-related Quality of Life After Kidney Transplantation in a Cohort of 232 Thai Patients

Junchotikul, P.; Charoenthanakit, C.; Saiyud, A.; Parapiboon, Watanyu; Ingsathit, Atiporn; Jirasiritham, S.; Sumethkul, V.

doi:10.1016/j.transproceed.2015.02.018

Cited by 22 publications

(21 citation statements)

References 5 publications

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“…6,19,20,22,23 In the current study, apart from work status, comparison of baseline and posttransplant HRQoL scores indicated significant improvements in all domains, which is consistent with most longitudinal studies summarized in Table S1, Supporting Information and studies of questionable validity, that included assessment of pre-and post-transplant HRQoL by recall, more than 12 months after transplantation, 24 and up to 10 years after transplantation. 25 However, not all studies show improvement. Gross et al 6 reported that kidney transplant recipients had sustained improvements in mental health but a decline in physical health components 1-3 years after transplantation, whereas a decline in physical health but sustained improvement in mental health above pretransplant levels was seen in SPK recipients over the same period.…”

Section: Discussionmentioning

confidence: 99%

“…The SF‐36 domains that have been reported to show most improvement post‐transplantation are role‐physical, vitality and general health . In the current study, apart from work status, comparison of baseline and post‐transplant HRQoL scores indicated significant improvements in all domains, which is consistent with most longitudinal studies summarized in Table S1, Supporting Information and studies of questionable validity, that included assessment of pre‐ and post‐transplant HRQoL by recall, more than 12 months after transplantation, and up to 10 years after transplantation . However, not all studies show improvement.…”

Section: Discussionmentioning

confidence: 99%

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Health‐related quality of life following kidney and simultaneous pancreas kidney transplantation

et al. 2019

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Introduction Kidney and simultaneous pancreas kidney (SPK) transplant recipients are younger and fitter than most other dialysis patients, but are also more vulnerable in areas of social, emotional and physical interaction. Few studies have tracked their post‐transplant health‐related quality of life (HRQoL). Aim To assess HRQoL following kidney and SPK transplantation, with comparison to dialysis patients, people with multiple co‐morbidities and general population data. Methods Patients completed the Kidney Disease Quality of Life Short Form (KDQOL‐SF™) 1.3 to assess their pre‐transplant HRQoL within 4 weeks of transplantation and 12 months later. Demographic and laboratory data were collected on participating patients and on non‐participating patients at both time‐points. Results Of 118 patients who completed the baseline KDQOL‐SF™, 75 (57 kidney and 18 SPK) completed the 1 year survey. Compared to baseline, 12 months HRQoL scores improved in all domains except for work status, exceeded those of patients on dialysis and, except for emotional wellbeing and mental health, exceeded the scores of people with multiple co‐morbidities. For female transplant recipients, 12 months HRQoL scores were not statistically different from similarly aged women in the general population. Male transplant recipients had similar scores for bodily pain and energy/fatigue, but lower scores in other domains. Compared to kidney‐only transplant recipients, SPK recipients achieved higher scores in work and sleep domains. Conclusion Improvements in most HRQoL domains occur within 1 year of kidney or SPK transplantation, and women achieve similar HRQoL to women in the general population. These data are encouraging for patients contemplating transplant listing.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Health‐related quality of life following kidney and simultaneous pancreas kidney transplantation

et al. 2019

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“…It is generally believed that renal transplantation improves the quality of life of kidney transplant recipients (KTR) compared to dialysis treatments . However, a meta‐analysis published in 2007 has shown that the difference in health‐related quality of life measured by the SF‐36 instrument between KTR and hemodialysis patients was significantly reduced after controlling for age and diabetes .…”

Section: Introductionmentioning

confidence: 99%

“…1,2 It is generally believed that renal transplantation improves the quality of life of kidney transplant recipients (KTR) compared to dialysis treatments. [3][4][5][6] However, a meta-analysis published in 2007 has shown that the difference in health-related quality of life measured by the SF-36 instrument between KTR and hemodialysis patients was significantly reduced after controlling for age and diabetes. 7 Nevertheless, the recent systematic review by Tonelli et al has clearly shown that quality of life was significantly and substantially better among transplant recipients.…”

Section: Introductionmentioning

confidence: 99%

Fatigue in kidney transplant recipients

Bossola

Pepe

Vulpio

2016

Clinical Transplantation

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Fatigue is still present in approximately 40%-50% of kidney transplant recipients (KTR), rates comparable to that of the hemodialysis population. Correlates of fatigue include inflammation, symptoms of depression, sleep disorders, and obesity. Fatigue in KTR determines a significant severe functional impairment, either when globally considered or when analyzed at the level of the single domains such as sleep and rest, homemaking, mobility, social interaction, ambulation, leisure activities, alertness behavior, and work limitations. In addition, fatigue in KTR is significantly associated with a severe deterioration of quality of life. Fatigue is very common among KTR poorly adherent to immunosuppressive therapy. Unfortunately, there is no evidence of studies about the treatments of this symptom in KTR. Efforts to detect and treat fatigue should be a priority in order to improve quality of life of KTR.

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“…Kidney transplant is one of the treatments in patients with ESRD (end stage renal disease) that increases the quality of life in patients (1)(2)(3). Following kidney transplant, patients need glucocorticoid and immunosuppressant drugs (4,5).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Asymptomatic Avascular Necrosis of the Hip in Patients With Kidney Transplantation

Kazemi

Samimagham

Tamaddondar³

et al. 2016

Acta Healthmedica

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Introduction: Kidney transplant is one of the treatments in patients with ESRD (end stage renal disease) that increases the quality of life in patients. Following kidney transplant, patients need glucocorticoid and immunosuppressant drugs. These drugs put patients in risk of hip avascular necrosis. The purpose of this study was to evaluate the prevalence of asymptomatic avascular necrosis of the hip in patients with kidney transplantation. Methods: This prospective descriptive cross-sectional study was conducted on all patients referred to the Shahid Mohammedi Hospital, Bandar Abbas, Iran, who had a kidney transplant at least six month before our study. All patients' information was collected with a questionnaire consisting of demographic information including age, sex, weight, height, history of hemodialysis, history of peritoneal dialysis, history of smoking, alcohol intake, history of prednisolone and the main variable data of the disease, including the causes of ESRD such as diabetes, hypertension and diabetes combined, polycystic kidney disease, IgA nephropathy reflux disease, focal segmental glomerulonephritis and time elapsed after the transplant. Magnetic resonance imaging (MRI) was used for the detection of avascular necrosis. Diagnosis of avascular necrosis was confirmed by two separate radiologists. Data was analyzed using IBM SPSS 21.0 software. Results: In this study, 83 patients were studied. Among these patients, 45 (54.2%) were male and 38 (45.8%) were female. The average age of the subjects was 41.29 ± 13.72 years. Demographic variables were similar in two groups. There was no relation among the vertebrae and overall results densitometry with avascular necrosis (p>0.05) . Based on this chart, prevalence of avascular necrosis in patients with osteoporotic hip based on densitometry, was significantly more than other people (p = 0.008). Conclusion: According to results, prevalence of femoral head avascular necrosis is not higher in patients after transplant and it has no significant relation to age, sex, BMI, time passed after transplant, CMV infection, hospitalization, history of dialysis or type of donator. Also, there was no significant correlation between the vertebra densitometry and the overall results of densitometry with avascular necrosis on MRI. The only factor associated with avascular necrosis in this study, was osteoporosis in the hip densitometry.

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Assessment of the Changes in Health-related Quality of Life After Kidney Transplantation in a Cohort of 232 Thai Patients

Cited by 22 publications

References 5 publications

Health‐related quality of life following kidney and simultaneous pancreas kidney transplantation

Health‐related quality of life following kidney and simultaneous pancreas kidney transplantation

Fatigue in kidney transplant recipients

Prevalence of Asymptomatic Avascular Necrosis of the Hip in Patients With Kidney Transplantation

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