Assessment of the Annexin A2 as a Predictive Biomarker for the Severity of Disseminated Intravascular Coagulation in Acute Leukemia Patients
Dhuha Aljuboory,
Intisar Sharba
Abstract:Annexin A2, also known as ANXA2, is a protein that controls cellular development and is reliant on calcium to bind to phospholipids. ANXA2 has a role in a variety of pathophysiological processes, including the shift from epithelial to mesenchymal cells, fibrinolysis, and cancer treatment resistance. By stimulating the MYC-HIF1A-VEGF signaling cascade, ANXA2 made it easier for esophageal squamous carcinoma cells to migrate and invade surrounding tissue. Our study showed the DIC score with D-Dimer and ANXA2 had … Show more
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