Assessment of tear secretion and tear film instability in cases with pterygium and normal subjects

Abstract

Introduction: Dry eye is a common disorder affecting a significant percentage of the population. Materials and methods: This study is a prospective, hospital-based, case-controlled study conducted between January 2009 and May 2010. Seventy-six pterygium cases and 152 age-and-sex matched controls presenting to the OPD of Manipal Teaching Hospital were included. The TBUT Schirmer's test and basal tear secretion were estimated in all patients. A TBUT of less than 10 seconds and a Schirmer's test of less than 10 mm were considered abnormal. Results: Pterygium was bilateral in 15 (19.7 % ) and unilateral in 61 (80.3 %) patients. Ninety-two (92.1 %) pterygium patients reported either one or more of the six dry eye symptoms. Redness was the most common (67 %) symptom reported. The mean Schirmer's test I, mean basal secretion and mean TBUT values were 16.19 mm, 10.01 mm and 10.56 seconds in pterygium cases and 20.22 mm,13.25 mm and 26.25 seconds in the control group respectively. There was a statistically significant difference in the dry eye results between the pterygium cases and the control group (p value < 0.05). The odds ratio between pterygium and dry eye was 3.28. Dry eye was present in 26 % of the normal patients and in 54 % of the pterygium cases. Conclusion: There is a strong relationship between dry eye and pterygium.

Clinical correlation between dry eye and pterygium: a study done at government medical college Jammu, Jammu and Kashmir, North India

“…Roka N et al also found that redness was the most common symptom of pterygium patients followed by grittiness and burning sensation. 4 Ganeshpuri AS et al also found that burning sensation, grittiness and redness were the common symptoms of pterygium patients.…”

“…4 Ganeshpuri AS et al in India had found strong relationship between dry eye, diabetes and pterygium.…”

“…18 Roka N et al had also found that the mean basal secretion was 10.01 mm in pterygium patients and 13.25 mm in the control group and also there was statistical significant difference between the two groups (p<0.05). 4 …”

“…The aqueous tear deficiency state is subdivided into Sjogren's syndrome-associated keratoconjunctivits sicca and nonSjogren's KCS (non-SS-KCS). 4 The definition and classification of dry eye was updated in 2007 during the tear film and ocular surface (TFOS) dry eye work shop (DEWS). Dry eye is a multifactorial disease of the tears and ocular surface that results in symptoms of discomfort, visual disturbance and tear film instability with potential damage to the ocular surface.…”

Primer ve Nüks Pterjium Cerrahisinde Limbal Konjonktival Otogreft Uygulamalarımız ve Sonuçları

“…17,18 Daha önceki çalışmalarda kuru göz ve inflamasyon arasındaki ve kuru göz ve pterjium arasındaki pozitif ilişki gösterilmiştir. 19,20 Bu nedenle bizim çalışmamızda inflamasyonu ve oküler yüzey hasarını azaltması ve inflamatuvar yıkım ürünlerini oküler yüzeyden uzaklaştırması açısından siklosporin A'ya ilave olarak hidroksipropilmetilselüloz suni gözyaşı 4x1 eklenilmiştir. Siklosporin A+hidroksipropilmetilselüloz kullanan gruplardan grup 2'de hiç nüks görülmezken grup 1'de bir olguda nüks geliştiği görülmüştür.…”