Assessment of Some Coagulation Parameters among Clients on Hormonal Contraceptive in a Tertiary Health Facility in Sokoto, North Western, Nigeria

O, Erhabor; Iz, Isaac; Au, Kaoje; Rt, John; Sa, Suleiman

doi:10.4172/2329-8790.1000139

Cited by 1 publication

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References 15 publications

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“…It is utilized in conjunction with PT, which is a test that examines the extrinsic pathway. Patients who have their PT and APTT shortened are at a higher risk of thrombosis (25,26).Thrombophilia is caused by coagulation abnormalities that occur as a result of diabetes mellitus, according to numerous studies. Hyperglycemia, which is also a distinguishing hallmark of diabetes, appears to be the cause of the coagulation abnormalities seen in diabetic individuals (27,28).…”

Section: Discussionmentioning

confidence: 99%

Evaluating some haemostatic profiles and platelet aggregation in gestational diabetes mellitus subjects

Atere¹,

Kosamat²,

Adeyemi³

et al. 2023

REJHS

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Background: Hypercoagulability has been linked to an increase in risk factors, making diabetes a major cause of morbidity and mortality in low-income countries like Nigeria. This research examined some haemostatic parameters in women with gestational diabetes mellitus (GDM).Methodology: A total of 100 subjects consisting of 40 GDM, 30 non-gestational diabetes pregnant women (NGPW) attending the ante-natal clinic of the hospital and 30 women with neither diabetes nor pregnancy (NDNP) were enrolled as controls in this study. Ten milliliters of blood was collected and dispensed into an appropriate anticoagulant bottle. Prothrombin time (PT), Activated partial Thromboplastin Time (APTT), complete blood count (CBC) and fasting blood sugar (FBS) was estimated using standard techniques.Results: There was a significantly higher in the mean values of FBS, PT, APTT and WBC among GDM and NGPW when compared with NPNP (p<0.05), while PCV was lower. FBS has positive correlation with PT and APTT while it shows negative correlation with platelet. APTT had a little edge over PT with higher area under the ROC curve of 0.997 than PT among GDM.Conclusion: In this study, women with GDM have considerably longer PT and APTT than NGPW and NDNP. Therefore, there may be possibility of haemorrhagic complications in gestational diabetes.

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Section: Discussionmentioning

confidence: 99%

Evaluating some haemostatic profiles and platelet aggregation in gestational diabetes mellitus subjects

Atere¹,

Kosamat²,

Adeyemi³

et al. 2023

REJHS

View full text Add to dashboard Cite

show abstract

Assessment of Some Coagulation Parameters among Clients on Hormonal Contraceptive in a Tertiary Health Facility in Sokoto, North Western, Nigeria

Abstract: Background: Hormonal contraceptives are widely used, and contain different doses of estrogen and types of progestogen. However, these hormonal contraceptives may potentially be associated with some side effects of coagulopathy.

Cited by 1 publication

References 15 publications

Evaluating some haemostatic profiles and platelet aggregation in gestational diabetes mellitus subjects

Evaluating some haemostatic profiles and platelet aggregation in gestational diabetes mellitus subjects

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