Assessment of Solid Pulmonary Nodules or Masses Using Zero Echo Time MR Lung Imaging: A Prospective Head-to-Head Comparison With CT

Liu, Qianyun; Feng, Zhichao; Liu, Weiyin Vivian; Fu, Weidong; He, Lei; Cheng, Xiaosan; Zhong-liang, Mao; Zhou, Wenming

doi:10.3389/fonc.2022.812014

Front. Oncol.

2022

DOI: 10.3389/fonc.2022.812014

|View full text |Cite

Assessment of Solid Pulmonary Nodules or Masses Using Zero Echo Time MR Lung Imaging: A Prospective Head-to-Head Comparison With CT

Qianyun Liu

Zhichao Feng

Weiyin Vivian Liu³

et al.

Abstract: ObjectiveThe aim of this study is to determine the potential of zero echo time (ZTE) MR lung imaging in the assessment of solid pulmonary nodules or masses and diagnostic consistency to CT in terms of morphologic characterization.MethodsOur Institutional Review Board approved this prospective study. Seventy-one patients with solid pulmonary nodules or masses larger than 1 cm in diameter confirmed by chest CT were enrolled and underwent further lung ZTE-MRI scans within 7 days. ZTE-MRI and CT images were compar… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article3

Relationship

Self Cite0

Independent3

Authors

Journals

Cited by 3 publications

References 31 publications

(36 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

Assessment of Lung Nodule Detection and Lung CT Screening Reporting and Data System Classification Using Zero Echo Time Pulmonary MRI

Wang,

Cui,

Wang

et al. 2024

Magnetic Resonance Imaging

View full text Add to dashboard Cite

BackgroundThe detection rate of lung nodules has increased considerably with CT as the primary method of examination, and the repeated CT examinations at 3 months, 6 months or annually, based on nodule characteristics, have increased the radiation exposure of patients. So, it is urgent to explore a radiation‐free MRI examination method that can effectively address the challenges posed by low proton density and magnetic field inhomogeneities.PurposeTo evaluate the potential of zero echo time (ZTE) MRI in lung nodule detection and lung CT screening reporting and data system (lung‐RADS) classification, and to explore the value of ZTE‐MRI in the assessment of lung nodules.Study TypeProspective.Population54 patients, including 21 men and 33 women.Field Strength/SequenceChest CT using a 16‐slice scanner and ZTE‐MRI at 3.0T based on fast gradient echo.AssessmentNodule type (ground‐glass nodules, part‐solid nodules, and solid nodules), lung‐RADS classification, and nodule diameter (manual measurement) on CT and ZTE‐MRI images were recorded.Statistical TestsThe percent of concordant cases, Kappa value, intraclass correlation coefficient (ICC), Wilcoxon signed‐rank test, Spearman's correlation, and Bland–Altman. The p‐value <0.05 is considered significant.ResultsA total of 54 patients (age, 54.8 ± 11.9 years; 21 men) with 63 nodules were enrolled. Compared with CT, the total nodule detection rate of ZTE‐MRI was 85.7%. The intermodality agreement of ZTE‐MRI and CT lung nodules type evaluation was substantial (Kappa = 0.761), and the intermodality agreement of ZTE‐MRI and CT lung‐RADS classification was moderate (Kappa = 0.592). The diameter measurements between ZTE‐MRI and CT showed no significant difference and demonstrated a high degree of interobserver (ICC = 0.997–0.999) and intermodality (ICC = 0.956–0.985) agreements.Data ConclusionThe measurement of nodule diameter by pulmonary ZTE‐MRI is similar to that by CT, but the ability of lung‐RADS to classify nodes from MRI images still requires further research.Level of Evidence2Technical EfficacyStage 2

show abstract

Assessment of Lung Nodule Detection and Lung CT Screening Reporting and Data System Classification Using Zero Echo Time Pulmonary MRI

Wang,

Cui,

Wang

et al. 2024

Magnetic Resonance Imaging

View full text Add to dashboard Cite

show abstract

Zero-echo time MRI: an alternative method for the diagnosis of urinary stones in children

Ozcan,

Ozer,

Dogan

et al. 2024

Eur Radiol

View full text Add to dashboard Cite

Objectives To evaluate the potential of zero-echo time-magnetic resonance imaging (ZTE-MRI) in the assessment of urolithiasis and compare ZTE-MRI with computed tomography (CT) in pediatric patients. Materials and methods This was a single-center, prospective cross-sectional study conducted between April 2023 and December 2023. 23 patients (12 girls, 11 boys; mean age: 12.3, range 1–18) with urinary tract stones detected on non-enhanced abdominal CT were enrolled. The images were evaluated independently by two radiologists for the presence, and number of stones in the kidneys, ureters, and bladder. In the second session, two radiologists evaluated whether urinary tract stones could be detected by MRI compared to CT, and the maximum diameter of the stones was measured. The CT and MRI results were compared with the Wilcoxon test. The agreement between the results of the observers was examined using Spearman’s rho correlation coefficient and the intraclass correlation coefficient. Results A total of 58 urinary tract stones were detected by CT and 39 of these were detected by MRI. Most of the stones that MRI could not detect were < 5 mm and the detection sensitivity of MRI increased in correlation with stone size (p < 0.001). There was poor intermodality agreement for stones < 5 mm, substantial agreement for stones 5–10 mm, and almost perfect agreement for stones > 10 mm. Interobserver agreement for stone detection on MRI was almost perfect for stones > 10 mm and 5–10 mm and was substantial for stones < 5 mm. Conclusion ZTE-MRI is a promising modality for detecting urinary stones without radiation exposure in children. Clinical relevance statement Zero-echo time-magnetic resonance imaging is a potential method for identifying urinary stones in children and other populations who are particularly sensitive to radiation. Key Points Urinary system stone disease in children is increasing and imaging is needed for managing urolithiasis. Zero-echo time-magnetic resonance imaging (ZTE-MRI) had an accuracy of 81.8% and 93.7% for stones larger than 5 mm and 10 mm, respectively. ZTE-MRI is a potential non-irradiating method for the diagnosis and management of urolithiasis.

show abstract

Imaging of Solid Pulmonary Nodules

Woodworth,

Frota Lima,

Bartholmai

et al. 2024

Clinics in Chest Medicine

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Assessment of Solid Pulmonary Nodules or Masses Using Zero Echo Time MR Lung Imaging: A Prospective Head-to-Head Comparison With CT

Cited by 3 publications

References 31 publications

Assessment of Lung Nodule Detection and Lung CT Screening Reporting and Data System Classification Using Zero Echo Time Pulmonary MRI

Assessment of Lung Nodule Detection and Lung CT Screening Reporting and Data System Classification Using Zero Echo Time Pulmonary MRI

Zero-echo time MRI: an alternative method for the diagnosis of urinary stones in children

Imaging of Solid Pulmonary Nodules

Contact Info

Product

Resources

About