Assessment of Serum and Salivary Ceruloplasmin Level in Patients with Oral Lichen Planus

Abbas, Aws Waleed; Zaidan, Taghreed F.; Al-Barrak, Abduladheem Y. Abbood

doi:10.12816/0015225

Cited by 2 publications

(5 citation statements)

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“…Oxidative stress reaction is one of the most important factors in the pathogenicity of LP and the salivary and serum levels of ceruloplasmin, which has antioxidative activity, was significantly higher in patients with LP compared with healthy subjects [12]. However, in the present study, the salivary levels of transferrin in patients with LP were less than those in healthy subjects.…”

Section: Discussioncontrasting

confidence: 77%

“…Composition of the saliva can be affected by the method used for collecting samples and the degree of stimulation of salivary flow. In addition, proteolytic enzymes of the saliva might affect the stability of certain diagnostic markers [12,17,18]. Therefore, further studies are necessary to more accurately evaluate salivary markers for the diagnosis and treatment of patients.…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies have reported that oxidative stress reaction is one of the most important factors involved in the pathogenicity of lichen planus. In this context, the concentration of ceruloplasmin, which has an antioxidative activity, was significantly higher in the saliva and serum of patients with lichen planus [12]. In addition, the total antioxidative capacity was lower in patients with lichen planus [13].…”

Section: Introductionmentioning

confidence: 87%

“…3) Use of medications interfering with the antioxidative defense system during the last three months; 4) Affliction with other systemic conditions such as diabetes, hyperthyroidism and iron deficiency anemia during the previous three months and 5) Use of vitamin supplements during the previous three months [12,13].…”

Section: Methodsmentioning

confidence: 99%

“…Then the samples were frozen at -80°C until the samples were prepared. An ELISA kit was used to determine salivary levels of transferrin [12,13].…”

Section: Data Collectionmentioning

confidence: 99%

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Salivary Transferrin Levels in Patients with Oral Lichen Planus

Falsafi

Khorshidi-Khiavi

Ghanizadeh

et al. 2019

Pesqui. bras. odontopediatria clín. integr.

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Objective: To compare salivary transferrin levels between patients with oral lichen planus (OLP) and healthy subjects. Material and Methods: In this descriptive, analytical, crosssectional study, 11 patients with OLP and 22 healthy subjects were selected after matching in terms of age and gender. OLP was confirmed by two oral medicine specialists based on clinical and histopathological criteria. Salivary samples were collected by spitting. The patients were asked to collect their saliva in their oral cavity and then evacuate it into sterilized Falcon tubes. The procedure was repeated every 60 seconds for 5-15 minutes. A total of 5 mL of saliva was collected using this method. The samples were collected from 8 to 9 in the morning in a fasting state to avoid circadian changes. The collected salivary samples were immediately placed next to ice and transferred to the laboratory to be centrifuged at 4°C at 800 g to isolate squamous cells and cellular debris. Then the samples were frozen at-80°C until the samples were prepared. An ELISA kit was used to determine salivary transferrin levels. Data were analyzed with descriptive statistics (means and standard deviations) and t-test for independent groups using SPSS 17. Statistical significance was set at p<0.05. Results: The mean salivary transferrin concentrations in patients with OLP and healthy subjects were 0.9055±0.28229 and 1.5932±0.80041 mg/dL, respectively (p<0.05). Conclusion: The salivary transferrin levels in patients with OLP were significantly lower than those in healthy subjects.

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Section: Discussioncontrasting

confidence: 77%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 87%

Section: Methodsmentioning

confidence: 99%

“…Then the samples were frozen at -80°C until the samples were prepared. An ELISA kit was used to determine salivary levels of transferrin [12,13].…”

Section: Data Collectionmentioning

confidence: 99%

See 3 more Smart Citations

Salivary Transferrin Levels in Patients with Oral Lichen Planus

Falsafi

Khorshidi-Khiavi

Ghanizadeh

et al. 2019

Pesqui. bras. odontopediatria clín. integr.

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Comparasion between Salivary biomarkers (macrophage inflammatory protein-1α and 1β ) in patients with oral lichen planus and patients with oral lichen planus and skin lesions

Al Bistanchy,

Al-Drobie

2023

Kufa Jour. Bio.

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''Background'':((Oral.lichen.planus.(OLP).is.a.prevalent.chronic.inflammatory.oral.mucosal disease.that.is.T-cell.immune.driven..Oral.lichen.planus.has.not.yet.been.linked.to.a.specific etiology..It.has.been.suggestedthat.immune.cell-mediated.aberrances.are.the.cause..Macrophage inflammatory.protein-1α.(MIP -1α).and.macrophage.inflammatory.protein-.1β.(MIP- 1β).may.be involved.in.the.etiology.of.this.condition,.according.to.a.number.of.experts..As.a.predisposing factor.in.the.development.of.oral.lichen.planus, MIP -1α and.MIP- 1β.have.been.studied.for.their potential.effects)).

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Assessment of Serum and Salivary Ceruloplasmin Level in Patients with Oral Lichen Planus

Cited by 2 publications

References 0 publications

Salivary Transferrin Levels in Patients with Oral Lichen Planus

Salivary Transferrin Levels in Patients with Oral Lichen Planus

Comparasion between Salivary biomarkers (macrophage inflammatory protein-1α and 1β ) in patients with oral lichen planus and patients with oral lichen planus and skin lesions

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