Seismic risk is fundamental for the establishment of priorities in long-term prevention policy since urbanization and concentration of population in earthquake prone areas are increasing. To assess seismic risk, it is necessary to determine seismic hazard and vulnerability for which large amount of input data is required. Therefore, a rapid seismic risk assessment is proposed, based on seismic hazard maps and on statistical Census data for buildings. A case study is illustrated for Croatian cities in order to provide an overview of the overall relative risk in Croatia. As a result, the prediction model for threatened buildings in Croatia in function of peak ground acceleration is proposed. The prediction model gives an indicative outcome after possible earthquake event expressed in terms of percentage of threatened buildings. Most vulnerable cities according to prediction model are Dubrovnik, Zagreb, Split and Rijeka in accordance with their buildings distribution by age.