Assessment of role of serum uric acid as a predictor of gestational diabetes mellitus

Maternal uric acid levels and risk of gestational diabetes mellitus: A systematic review and dose–response meta‐analysis of cohort studies including 105,380 participants

“…Furthermore, 19 studies were excluded after the full-text screening. Finally, 23 studies were eligible for inclusion in the present study [18][19][20][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44] . Table 1 summarizes the characteristics of the included studies.…”

“…The mean age of pregnant women was approximately 29 years. The maternal blood uric acid concentration during pregnancy was measured in 21 of 23 studies at or before the 20th week of gestation [18][19][20]25,[27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43] , and the remaining studies measured it after the 20th week of gestation 26,44 . The maternal blood uric acid concentration during pregnancy was measured using calorimetric assays 18,20,25,27,28,[30][31][32][33][36][37][38][39]41 or a spectrometric method 29 , whereas eight out of 23 included studies did not provide data regarding the method of maternal blood uric acid measurement 19,26,34,35,40,[42][43][44] .…”

“…The maternal blood uric acid concentration during pregnancy was measured in 21 of 23 studies at or before the 20th week of gestation [18][19][20]25,[27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43] , and the remaining studies measured it after the 20th week of gestation 26,44 . The maternal blood uric acid concentration during pregnancy was measured using calorimetric assays 18,20,25,27,28,[30][31][32][33][36][37][38][39]41 or a spectrometric method 29 , whereas eight out of 23 included studies did not provide data regarding the method of maternal blood uric acid measurement 19,26,34,35,40,[42][43][44] . Among the 23 included studies, five studies collected blood samples after 8-12 h of fasting for the measurement of maternal uric acid…”

“…The maternal blood uric acid concentration during pregnancy was measured using calorimetric assays 18,20,25,27,28,[30][31][32][33][36][37][38][39]41 or a spectrometric method 29 , whereas eight out of 23 included studies did not provide data regarding the method of maternal blood uric acid measurement 19,26,34,35,40,[42][43][44] . Among the 23 included studies, five studies collected blood samples after 8-12 h of fasting for the measurement of maternal uric acid 19,27,33,34,39 ; the remaining studies did not report the method by which blood samples were collected 18,20,25,26,[28][29][30][31][32][35][36][37][38][40][41][42][43][44] . Among the studies included in this systematic review, 13 studies were carried out on participants who were primiparous or multiparous…”

“…Among the 23 included studies, five studies collected blood samples after 8-12 h of fasting for the measurement of maternal uric acid 19,27,33,34,39 ; the remaining studies did not report the method by which blood samples were collected 18,20,25,26,[28][29][30][31][32][35][36][37][38][40][41][42][43][44] . Among the studies included in this systematic review, 13 studies were carried out on participants who were primiparous or multiparous 18,25,[29][30][31]33,[35][36][37][38][39][40]43 , seven studies were carried out on participants who were primiparous 19,20,26,27,32,41,44 and four studies did not mention the participants' parity status 28,34,42 . Furthermore, out of all eligible studies, no studies have been carried out on pregnant women who were multiple pregnancies (two or more babies ...…”