Assessment of regional and global left ventricular function by reinjection Tl-201 and rest Tc-99m sestamibi ECG-gated SPECT

Tadamura, Eiji; Kudoh, Takashi; Motooka, Makoto; Inubushi, Masayuki; Shirakawa, Seiji; Hattori, Naoya; Okada, Tomohisa; Matsuda, Tetsuya; Koshiji, Takaaki; Nishimura, Kazunobu; Matsuda, Katsuhiko; Konishi, Junji

doi:10.1016/s0735-1097(98)00661-5

Cited by 106 publications

(69 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The resultant temporal resolution of 21–42 ms was provided according to the individual heart rate. Cine MR images of 10–12 contiguous sections, 8 mm thick, with an interslice gap of 2 mm were obtained in the short-axis planes, covering the entire left ventricle from the base to the apex, to acquire 3-dimensional LV data [15,16,17]. In addition, cine MR images were acquired in the vertical and horizontal long-axis planes.…”

Section: Methodsmentioning

confidence: 99%

Left Ventricular Functional Analysis Using 64-Slice Multidetector Row Computed Tomography: Comparison with Left Ventriculography and Cardiovascular Magnetic Resonance

Tadamura²,

Kanao³

et al. 2007

Cardiology

Self Cite

View full text Add to dashboard Cite

Objective: The progress in computed tomography (CT) has improved temporal resolution and shortened the acquisition time. We compared cardiac function using 64-slice CT with left ventriculography (LVG) and cardiovascular magnetic resonance (CMR). Methods: A head-to-head comparison between CT, LVG and CMR was performed in 41 patients. In global LV function, CMR served as the reference. Regional wall motion was compared in a 5-point scoring system. Results: CT had excellent intra- and interobserver reproducibility. Ejection fraction, end-diastolic and end-systolic volumes by CT were closely correlated with CMR (r = 0.95, 0.96 and 0.98, respectively), while LVG underestimated LV volumes (p < 0.01). The standard deviation of ejection fraction difference between CT and CMR was significantly lower than that between LVG and CMR (p = 0.0015). In regional function, there were good agreements of 94.8% (ĸ = 0.82) between CT and LVG and 94.5% (ĸ = 0.84) between CT and CMR. The intermethod agreements in mild hypokinesis using CT tended to be lower. Conclusion: An excellent correlation was observed between CT and CMR in the LV function over a wide range of heart rates. However, even though 64-slice CT tended to be less sensitive in detecting mild hypokinesis, it still showed excellent concordance in advanced regional abnormalities.

show abstract

Section: Methodsmentioning

confidence: 99%

Left Ventricular Functional Analysis Using 64-Slice Multidetector Row Computed Tomography: Comparison with Left Ventriculography and Cardiovascular Magnetic Resonance

Tadamura²,

Kanao³

et al. 2007

Cardiology

Self Cite

View full text Add to dashboard Cite

show abstract

“…In spite of this, it has been validated against other modalities (cMRI and first pass ERNA) [8]. Also Iskandarian et al [19] and Tadamura [20] found a good correlation between gated SPECT and cMRI in patients with myocardial infarction.…”

Section: Discussionmentioning

confidence: 99%

Comparison between 99mTc-sestamibi gated myocardial perfusion SPECT and echocardiography in assessment of left ventricular volumes and ejection fraction — effect of perfusion defect and small heart

Danesh-Sani

Oskoueian²,

Kakhki

2014

Nucl. Med. Rev.

View full text Add to dashboard Cite

show abstract

“…Today, this modality provides multiplane dynamic images of the beating heart with excellent spatial resolution and temporal resolution of 30 phases per cardiac cycle, which is comparable to what has been for many years the standard frame rate in 2D echocardiography. The combination of these features places CMR imaging as the tentative "gold standard" for LV size and function, as reflected by multiple publications in which it was used as such to validate other noninvasive techniques (3)(4)(5)(6)(7)(8)(9)(10)(11)(12).…”

Section: Discussionmentioning

confidence: 99%

“…trast resolution that has become the standard reference in the assessment of left ventricular (LV) size and function (1,2), against which other techniques are frequently validated (3)(4)(5)(6)(7)(8)(9)(10)(11)(12). However, this technique relies on the detection of endocardial boundaries, which requires frame-by-frame manual tracing on multiple slices, and is thus of limited value in clinical practice.…”

mentioning

confidence: 99%

Automated frame‐by‐frame endocardial border detection from cardiac magnetic resonance images for quantitative assessment of left ventricular function: Validation and clinical feasibility

Corsi

Veronesi

Lamberti

et al. 2009

Magnetic Resonance Imaging

View full text Add to dashboard Cite

Purpose: To develop a technique based on image noise distribution for automated endocardial border detection from cardiac magnetic resonance (CMR) images throughout the cardiac cycle, validate it, and test its clinical utility. Materials and Methods:Images obtained in 36 patients were analyzed using custom software to obtain left ventricular (LV) volume throughout the cardiac cycle, end-systolic and end-diastolic LV volumes, and ejection fraction (EF). Validation against manually-traced endocardial boundaries included intertechnique comparisons of LV volumes, slice areas, and border positions. Then, the clinical feasibility of the dynamic automated analysis of LV function was tested in 14 patients with normal LV function, 12 patients with systolic dysfunction, and 10 patients with diastolic dysfunction.Results: Analysis time for one cardiac cycle was Ͻ15 minutes. Intertechnique comparisons resulted in high correlation (r Ͼ 0.96), small biases (volumes: -6 mL; EF: 4.6%) and narrow limits of agreement (volumes: 17.6 mL; EF: 9.2%). We found significant intergroup differences in multiple quantitative indices of systolic and diastolic function. Conclusion:Fast, automated, dynamic detection of LV endocardial boundaries is feasible and allows accurate quantification of LV size and function, which is potentially clinically useful for objective assessment of systolic and diastolic dysfunction. CARDIAC MAGNETIC RESONANCE (CMR) is a noninvasive imaging modality with excellent spatial and contrast resolution that has become the standard reference in the assessment of left ventricular (LV) size and function (1,2), against which other techniques are frequently validated (3-12). However, this technique relies on the detection of endocardial boundaries, which requires frame-by-frame manual tracing on multiple slices, and is thus of limited value in clinical practice. Moreover, continuous measurement of LV volume requires slice-by-slice, phase-by-phase detection of the endocardial boundaries, which with the commercially available analysis software packages, based on the analysis of image intensity gradients, requires manual corrections in most patients and thus remains semiautomated at best, time consuming, and subjective. Thus, the dynamic nature of CMR imaging is largely unutilized in the clinical assessment of LV function, which is commonly reduced to visually identifying in a small number of slices the end-systolic (ES) and end-diastolic (ED) frames as those that depict the smallest and largest cross-sectional LV cavity areas, respectively. These frames are then traced slice-by-slice and used to obtain ES and ED volumes (ESV and EDV) and calculate the ejection fraction (EF). This practical solution can be challenging in patients with severely reduced systolic function, when volume changes are minimal, and inaccurate in hearts, wherein ventricular contraction is uneven and dyssynchronized so that minimum and maximum cross-sectional areas may appear in different slices at different times. Availability of a reliable technique f...

show abstract

Assessment of regional and global left ventricular function by reinjection Tl-201 and rest Tc-99m sestamibi ECG-gated SPECT

Abstract: Reinjection- and MIBI-g-SPECT provide clinically satisfactory various functional data. These functional data in combination with the perfusion information will improve diagnostic and prognostic accuracy without an increase in cost or the radiation dose to the patients.

Cited by 106 publications

References 19 publications

Left Ventricular Functional Analysis Using 64-Slice Multidetector Row Computed Tomography: Comparison with Left Ventriculography and Cardiovascular Magnetic Resonance

Left Ventricular Functional Analysis Using 64-Slice Multidetector Row Computed Tomography: Comparison with Left Ventriculography and Cardiovascular Magnetic Resonance

Comparison between 99mTc-sestamibi gated myocardial perfusion SPECT and echocardiography in assessment of left ventricular volumes and ejection fraction — effect of perfusion defect and small heart

Automated frame‐by‐frame endocardial border detection from cardiac magnetic resonance images for quantitative assessment of left ventricular function: Validation and clinical feasibility

Contact Info

Product

Resources

About