Assessment of quality of life among school children with atopic dermatitis in a locality in Cairo

Hassab-El-Naby, Hussein M.M.; Mohamed, Yaser F.; Ammar, Morsy A.; Mostafa, Amr M.

doi:10.1097/01.ewx.0000392815.83337.7f

Cited by 4 publications

(5 citation statements)

References 8 publications

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“…Not surprisingly, in our study, the quality of life of children with AD was found to have a significant relationship with the severity of disease, which is consistent with the findings of numerous authors worldwide. 6,16,18,19 The occurrence of pruritus as a major contributor to the magnitude of the QoL scores, also displayed a similar trend in comparison to the existing literature. 2,5,20 In addition to this, the sleep latency and quality of sleep also contributed heavily to the QoL scores, which might be secondary to the occurrence of night pruritus.…”

Section: Correlation With Patient Variablessupporting

confidence: 75%

Atopic dermatitis in children: a cross-sectional study of its impact on quality of life

Babu,

Thomas,

Zacharias

et al. 2024

Int J Contemp Pediatr

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Background: Atopic dermatitis, characterized by chronic inflammation of the skin, manifests with symptoms such as itching, skin discomfort, and sleep disturbances, significantly impacting the physical health and daily functioning of affected children. We embarked on this study to assess the Quality of Life of children with AD, identify factors that influence their QoL, and determine the specific domains of QoL most affected by the condition. Methods: Children up to 16 years of age, who met the Hanifin and Rajka’s diagnostic criteria for AD, were identified. The severity of AD was assessed using the severity scoring of atopic dermatitis index, and QoL was assessed using validated questionnaires: the infants dermatitis quality of life index for children under 4 years and the children’s dermatology life quality index for children 4 years and above. Results: A total of 70 children with AD were enrolled in the study. The mean QoL (IDQOL/CDLQI) score for children with AD was 6.7±5.05 and QoL was significantly impaired in children with more severe disease. The domains of QoL most affected by AD were related to pruritus, sleep disturbances, mood changes and treatment related issues. The duration of illness and the presence of other atopic comorbidities showed a significant correlation with QoL impairment, whereas age, gender and socioeconomic status demonstrated no such correlation. Conclusions: This study highlights the substantial impact of AD on the QoL of affected children, especially due to symptoms like itching and sleep disturbances.

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Section: Correlation With Patient Variablessupporting

confidence: 75%

Atopic dermatitis in children: a cross-sectional study of its impact on quality of life

Babu,

Thomas,

Zacharias

et al. 2024

Int J Contemp Pediatr

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“…A significant positive correlation was observed between obj-SCORAD scores and QOL scores (that is, the greater the disease severity, the greater the QOL impairment). This compares with the results of studies among children with AD in Italy, [37] Egypt [30] and the UK. [31] Hassabel-Naby et al [30] in Egypt evaluated 100 school-aged children with AD recruited from a dermatology clinic, and observed significantly greater QOL impairment with increasing disease severity.…”

Section: Articlesupporting

confidence: 60%

“…This compares with the results of studies among children with AD in Italy, [37] Egypt [30] and the UK. [31] Hassabel-Naby et al [30] in Egypt evaluated 100 school-aged children with AD recruited from a dermatology clinic, and observed significantly greater QOL impairment with increasing disease severity. By contrast, Van Valburg et al, [9] in a study of preschool children with AD recruited from a general practice clinic, reported no significant association between QOL scores and obj-SCORAD scores, which was probably a result of using a proxy estimation of QOL and there being a larger proportion of individuals with mild disease.…”

Section: Articlesupporting

confidence: 60%

“…However, the observed mean score was comparable to the 9.8 (4.5) observed among children with AD in Egypt. [30 The high mean QOL score observed in the index study may be attributed to the high proportion of individuals with moderate to severe disease, which was also the case in the Egyptian study; over 80% of subjects had moderate to severe disease in both studies. Lower mean QOL scores have been documented among children with AD recruited from general practice clinics, owing to a lower proportion of severe cases.…”

Section: Discussionmentioning

confidence: 55%

“…The mean (SD) obj-SCORAD score in this study was 34.4 (17.2), which was comparable to the 27.9 (8.3) observed in Egypt. [30] This is not surprising, as both studies were carried out in dermatology clinics. However, lower mean obj-SCORAD scores were reported in general practice clinics in the UK [38] and the Netherlands.…”

Section: Articlementioning

confidence: 93%

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Impact of atopic dermatitis on the quality of life of Nigerian children: A hospital-based cross-sectional study

Puddicombe¹,

Odusote

Lesi

et al. 2018

S Afr J CH

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Background. Atopic dermatitis (AD) is the most common inflammatory skin disease in childhood. A skin disorder with a relapsing course, AD exerts a significant disease burden on affected children. However, there is a dearth of knowledge about the impact of AD on the quality of life (QOL) of affected children in Nigeria. Objectives. To examine the impact of AD on QOL in children of various age groups, and to identify the relationship between patient variables (age, gender, socioeconomic status), disease severity and QOL in AD. Method. This was a cross-sectional descriptive study of children with AD attending the dermatology clinic of Lagos University Teaching Hospital, Idi-Araba, Lagos, Nigeria. AD cases were recruited from new paediatric patients ≤16 years who attended the clinic over a 6-month period. English and Yoruba versions of the Infants' Dermatitis Quality of Life Index (IDQOL) and the Children's Dermatology Life Quality Index (CDLQI) were used to determine the QOL of the subjects. AD severity was evaluated using the Objective SCORing of Atopic Dermatitis (obj-SCORAD) index. Results. Forty-seven subjects with AD were identified. Their ages ranged from newborn to 16 years. The median(interquartile range (IQR)) IDQOL score was 6.0 (3.0 -15.5; n=25), and the median (IQR) CDLQI score was 9.5 (7.75 -17.75; n=22). The mean (standard deviation) obj-SCORAD score was 34.4 (17.2). The question on itching was the highest-scoring question in both QOL questionnaires. There was no significant difference in QOL across age, gender and socioeconomic status groups. However, greater QOL scores were significantly correlated with higher AD severity scores. Conclusion.The study confirms that AD impairs the QOL of affected children in all age groups. QOL assessments are relevant tools which provide a patient's perspective, thus improving the understanding of the impact of AD on afflicted individuals.

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Differences in Psychometric Properties of Clinician- and Patient-Reported Outcome Measures for Atopic Dermatitis by Race and Skin Tone: A Systematic Review

Kaundinya

Rakita

Feldman

et al. 2022

Journal of Investigative Dermatology

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Assessment of quality of life among school children with atopic dermatitis in a locality in Cairo

Cited by 4 publications

References 8 publications

Atopic dermatitis in children: a cross-sectional study of its impact on quality of life

Atopic dermatitis in children: a cross-sectional study of its impact on quality of life

Impact of atopic dermatitis on the quality of life of Nigerian children: A hospital-based cross-sectional study

Differences in Psychometric Properties of Clinician- and Patient-Reported Outcome Measures for Atopic Dermatitis by Race and Skin Tone: A Systematic Review

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