Assessment of quality of life determinants in hemodialysis patients of a developing country: A cross-sectional study during ongoing COVID-19 pandemic

Abstract

Background and Objectives: Patients of end-stage renal disease are prone to have a very low quality of life (QoL). Variety of factors influence the QoL among sufferers of chronic kidney disease comprising of type of dialysis, sufficiency/adequacy of dialysis, and associated burden of disease. We conducted this study amidst the pandemic to determine the associated factors for poor QoL in hemodialysis patients during the ongoing pandemic.Patients and Methods: This cross-sectional study was conducted in a hemodialysis unit of a tertiary care hospital. A total of 118 participants responded to the validated questionnaire of Quality of Life Index-dialysis version-III (QLI). Higher scores signify good QoL, total scores are further categorized into subgroups desirable, relatively desirable and undesirable.Results: The mean age of the participants was 57.36 ± 10.03 years and mean body mass index of 26.73 ± 5.54 kg/m 2 . The mean total QoL of the study population was found quite low (12.99 ± 5.89). Majority of respondents fell in undesirable category of QoL (49.2%). Total QoL (P = 0.004) and subscale health/functioning (P = 0.003) were significantly lower in females. All the subscales along with total QoL scores were found lower in twice-weekly dialyzed patients (P < 0.001). Marital status (P = 0.049) and twice-weekly dialysis (P < 0.001) were found significant with undesirable QoL. On multivariate analysis, significant determinants of undesirable QoL were twice-weekly dialysis (P = 0.001), catheter access (P = 0.034), phosphate (P = 0.005) and uric acid (P = 0.006).Conclusion: Inadequate dialysis due to lesser frequency per week leading to poorly cleared toxic substances were most significant contributors of poor QoL in our study.

Investigation of Perception of Quality of Life and Psychological Burden of Patients Undergoing Hemodialysis—Quality of Life of Hemodialysis Patients

“…A search of the literature for corresponding studies during this time period found similar results to those of the present study. Ashgar et al (2022) observed low QoL ( p > 0.001) in all subscales ( p = 0.003) [ 24 ].…”

Asosiasi Kadar Hemoglobin dan Indeks Massa Tubuh terhadap Kualitas Hidup Pasien Penyakit Ginjal Kronik Stadium 5 Hemodialisis

“…Hasil penelitian ini berbeda dengan penelitian-penelitian sebelumnya. Penelitian yang dilakukan oleh Asghar et al 22 pada tahun 2021, yang menilai asosiasi antara IMT dengan kualitas hidup pasien hemodialisis dengan menggunakan Quality of Life Index-dialysis version-III (QLI), menunjukkan terdapat asosiasi bermakna antara IMT dengan kualitas hidup pasien PGK yang melakukan terapi dialisis dua kali per minggu (p<0,001). Penelitian oleh Günalay et al 23 di İzmir Tepecik Training and Research Hospital pada tahun 2016, yang menilai hubungan antara malnutrisi dan kualitas hidup pasien hemodialisis menggunakan EQ-5D, menunjukkan bahwa skor kualitas hidup lebih rendah ditemukan pada pasien dengan malnutrisi dibandingkan dengan yang tidak malnutrisi (p=0,001).…”