Assessment of prostate tissue remodeling in rats exposed to bisphenol A and the phytoestrogens genistein and indole-3-carbinol during the perinatal period
Éricka Stéphanny Brandão Bueno,
Carlos Domingos Vieira Neto,
Alessandro Rodrigues
et al.
Abstract:Bisphenol A (BPA) is a compound known for its direct action on the prostate. Prostatic morphogenesis is a critical period when interference by any compound could permanently damage the organ. As such, the present study evaluated the morphological aspects resulting from gestational and lactational administration of BPA, indole-3-carbinol (I3C) and genistein (GEN) in prepubescent male rats. Pregnant Sprague Dawley females were allocated into 4 experimental groups and received the following: C: Control (no treatm… Show more
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