Assessment of Prescription Patterns in Hypertensive and Diabetic Patients Visiting Private Tertiary Care Hospital of Dharan Municipality, Nepal

Dahal, Prasanna; Maharjan, Laxman; Dahal, Bibek; Gupta, Kissan

doi:10.3126/stcj.v2i1.14798

Cited by 8 publications

(17 citation statements)

References 8 publications

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“…The finding is in consonance with similar studies. 9,10 This pattern of utilization is as per the recommendations of guidelines for diabetes management. 13,14 Sulfonylurea and insulin were other anti diabetic drugs prescribed as monotherapy.…”

Section: Discussionmentioning

confidence: 91%

“…The study findings are in consonance with similar studies. 9,10,12 The most common drug prescribed to the patients was metformin (89.27%) followed by glibenclamide (29.11%) and human mixtard insulin (15.28%). Glimepiride was prescribed in 8.29% prescriptions.…”

Section: Discussionmentioning

confidence: 99%

“…12 However, glimepiride was the most common sulfonylurea prescribed in other similar studies. 9,10 Insulin was prescribed to15.28% patients compared to 25% patients in study conducted by Rekha MB et al 12 These variations can be due to choice of physician in relation to type of patients, their concurrent illness as well as availability of medicines.…”

Section: Discussionmentioning

confidence: 99%

“…The finding is in consonance with other studies. 9,10 There were three anti diabetic drugs containing prescriptions were 20 (3.25%). Biguanide + sulfonylurea drugs were present in all three drugs containing prescriptions.…”

Section: Discussionmentioning

confidence: 99%

“…The finding is in consonance with other studies. 9,12 Average number of drugs prescribed in a prescription was 4.65±1.83. Average number of anti diabetic drugs in a prescription was 1.74±0.61.…”

Section: Discussionmentioning

confidence: 99%

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Prescribing pattern of anti diabetic drugs in patients suffering from type 2 diabetes mellitus with co-existing hypertension in a tertiary care teaching hospital

Sharma

Parmar

2018

Int J Basic Clin Pharmacol

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Background: Diabetes mellitus and hypertension frequently co-exist in a patient. In such patients, the risk of complications, morbidity and mortality increases. One should be careful in management and choosing drugs. Authors undertook this study to understand the prescribing pattern of the physicians in diabetic hypertensive patients.Methods: This cross sectional, observational study was conducted in type 2 diabetic outdoor patients with co-existing hypertension, for duration of one year. We used descriptive statistics to analyze data of 615 patients to determine prescribing pattern of drugs.Results: 93.17% of patients were more than 40 years of age. Ratio of female to male patients was 1.30. Mean duration of diabetes was 5.81 years. Multi drug anti diabetic regimes (54.47%) were common than monotherapy (43.90%). Commonly prescribed anti diabetic drug groups were biguanides (89.27%), Sulfonylureas (43.90%) and insulin (15.28%). Metformin (89.27%), glibenclamide (29.11%) and insulin (15.28%) were commonly prescribed anti diabetic drugs. Metformin was the most common monotherapy drug and biguanide + sulfonylurea was the most common two drug combination. Commonly prescribed drugs for co-morbid conditions were enalapril (83.41%), aspirin (30.41%), amlodipine (29.76%) atorvastatin (27.32%) and famotidine (26.34%). Average number of drugs prescribed in a prescription was 4.65. Prescriptions with injections were 15.93% and with brand names were 13.15%.Conclusions: Prescribing pattern of drugs was as per current practices and recommendations of guidelines. Still, there is room for improvement in choice of drug, prescribing drug with generic name and choosing drug from essential medicine list.

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Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Prescribing pattern of anti diabetic drugs in patients suffering from type 2 diabetes mellitus with co-existing hypertension in a tertiary care teaching hospital

Sharma

Parmar

2018

Int J Basic Clin Pharmacol

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Amlodipine-Induced Pedal Edema and Its Relation to Other Variables in Patients at a Tertiary Level Hospital of Kathmandu, Nepal

Khadka

Joshi

Shrestha

et al. 2018

Journal of Pharmacy Technology

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Vasodilatory edema is a frequently encountered side effect among hypertensive patients using antihypertensive drugs. Amlodipine and nifedipine are common drugs associated with vasodilatory edema. When used as monotherapy, calcium channel blockers (CCBs) are associated with a substantial risk of peripheral edema, including pedal edema, which is the most common reason for its discontinuation. 1 This is a dose-dependent adverse effect, so low-dose combination therapy is a preferred choice over high-dose monotherapy. It is less common with newer generation CCBs. 2 Reported rates of peripheral edema are dosedependent, ranging from 5% to 70% with a high dose. 3 Only 5% of pedal edema was seen with a 5 mg dose, 25% with a 10 mg dose, whereas >75% was seen with 20 mg of daily dose. 4 Ankle edema is developed mostly in women, elderly patients, those with heart failure, upright position, and those in humid environments. 5 CCB-related edema is caused by preferential arteriolar or precapillary dilation without commensurate dilation in the venous or postcapillary circulation. 3,6 The addition of an angiotensin 809005P MTXXX10.

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A study of prescribing pattern of antihypertensive drugs in hypertensive patients with co morbid diabetes in a tertiary care teaching hospital

Sharma

Parmar

Trivedi

2018

Int J Basic Clin Pharmacol

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Background: Hypertension and diabetes mellitus are among the commonest non-communicable diseases. Co-existence of hypertension and diabetes increases morbidity and mortality. So co-existence of these diseases requires attention and rational management. Studying current prescribing pattern of drugs provide data for recommendations and decisions regarding rational practice. We undertook this study to study prescribing pattern.Methods: It was cross sectional, observational, descriptive study in outdoor patients suffering from hypertension and type 2 diabetes mellitus for duration of one year. Data of 601 patients were analyzed using descriptive statistics to determine prescribing pattern of drugs.Results: In this study, 71.55% patients were above 50 years age. Female patients were 56.57%. Average duration of hypertension was 4.08 years. Commonly prescribed antihypertensive drug groups were angiotensin converting enzyme (ACE) inhibitors (85.36%) followed by β receptor blockers (33.44%) and calcium channel blockers (29.95%). Enalapril (85.36%) followed by amlodipine (29.95%) and atenolol (21.46%) were commonly prescribed antihypertensive drugs. Single antihypertensive drug was prescribed in 292 (48.59%) prescriptions. The most common monotherapy drug was enalapril (82.19%). Two antihypertensive drugs were prescribed in 231 (38.43%) prescriptions. The most common two drug combination was ACE inhibitors + β receptor blockers (40.69%). Four antihypertensive drugs were prescribed in only 1.50% prescriptions.Conclusions: From this study, the results suggest that the prescribing pattern of antihypertensive drugs reflects recommendations of current guidelines and practices. However, β receptor blockers were prescribed more commonly. There is room for improvement in choice of drugs.

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Assessment of Prescription Patterns in Hypertensive and Diabetic Patients Visiting Private Tertiary Care Hospital of Dharan Municipality, Nepal

Cited by 8 publications

References 8 publications

Prescribing pattern of anti diabetic drugs in patients suffering from type 2 diabetes mellitus with co-existing hypertension in a tertiary care teaching hospital

Prescribing pattern of anti diabetic drugs in patients suffering from type 2 diabetes mellitus with co-existing hypertension in a tertiary care teaching hospital

Amlodipine-Induced Pedal Edema and Its Relation to Other Variables in Patients at a Tertiary Level Hospital of Kathmandu, Nepal

A study of prescribing pattern of antihypertensive drugs in hypertensive patients with co morbid diabetes in a tertiary care teaching hospital

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