Assessment of Postoperative Pain After Laryngeal Surgery for Cancer

Mom, T.; Bazin, Jean-Étienne; Commun, F.; Dubray, Claude; Eschalier, Alain; Derbal, Catherine; Avan, Paul; Gilain, L.

doi:10.1001/archotol.124.7.794

Cited by 15 publications

(11 citation statements)

References 22 publications

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“…However, a study performed in men having undergone a partial or total laryngectomy demonstrated that postoperative pain decreases with time (Mom et al, 1998). This practice allows for an appropriate pain management at the time the pain is the most severe in the immediate postoperative period.…”

Section: Discussionmentioning

confidence: 99%

“…The time course of pain intensity during this period is not completely known. However, a study performed in men having undergone a partial or total laryngectomy demonstrated that postoperative pain decreases with time (Mom et al, 1998). In addition, postoperative pain intensity course can be extrapolated from studies reporting the use of rescue medication, with the highest morphine consumption during the 6 h following surgery (Hernandez-Palazon et al, 2001;Fletcher et al, 1997).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Analgesic efficacy and safety of intravenous paracetamol (acetaminophen) administered as a 2 g starting dose following third molar surgery

Juhl

Nørholt

Tønnesen

et al. 2006

European Journal of Pain

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Analgesic efficacy and safety of intravenous paracetamol (acetaminophen) administered as a 2 g starting dose following third molar surgery

Juhl

Nørholt

Tønnesen

et al. 2006

European Journal of Pain

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“…Pharyngolaryngeal cancer surgery is associated with a high level of pain in the early postoperative period [1]. The IV route is the common way of providing postoperative analgesia for pharyngolaryngeal surgery.…”

Section: Introductionmentioning

confidence: 99%

Dexmedetomidine in combination with sufentanil for postoperative analgesia after partial laryngectomy

et al. 2017

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BackgroundDexmedetomidine as an adjunct with opioids has been confirmed to spare opioids usage and improve analgesia for postoperative pain treatment. Furthermore, dexmedetomidine can attenuate the airway reflex. The aim of this study is to assess the safety and efficacy of dexmedetomidine combined with sufentanil for postoperative analgesia after partial laryngectomy.MethodsA total of 60 adult male patients were recruited and randomly allocated to receive sufentanil 1.0 μg ml−1 (Group S) or sufentanil 1.0 μg ml−1 plus dexmedetomidine 4 μg ml−1 (Group SD) for postoperative analgesia. The IV patient controlled analgesia (PCA) device was programmed to deliver 1.5 ml per demand with a 10 min lockout interval and 1.5 ml per hour background infusion. Cumulative consumption of sufentanil and pain intensity during 24 hour (h) after surgery were recorded. Coughing episodes per day, sleep quality, hemodynamic and respiratory profiles were measured.ResultsCompared with Group S, patients in Group SD required less sufentanil during the 0–24 h postoperative period (p < 0.0001) and reported significant lower pain intensity from the second postoperative hour to the end of the study (P < 0.0001). Daily coughing episodes, sleep disturbance was lower and patients’ satisfaction was higher in Group SD (P < 0.05). Decrease in heart rate and mean blood pressure from baseline at 1 h, 2 h, 3 h, 12 h, and 24 h after operation were significantly greater in Group SD (P = 0.00). The incidence of PCA related adverse events were comparable between the two groups.ConclusionDexmedetomidine/sufentanil combination for postoperatjve analgesia in partial laryngectomized patients resulted in significant sufentanil sparing, better analgesia, reduced frequency coughing episodes, and better sleep quality.Trial registrationChinese Clinical Registry (ChiCTR): ChiCTR-TRC-14004618, date of registration: 08 May 2014.

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“…Les chirurgies des cancers des VADS peuvent donner des douleurs postopératoires intenses, maximales dans les premières heures puis s'atténuant progressivement dans les 48 à 72 heures [2,3] (niveau de preuve 2). L'évaluation de la douleur doit tenir compte des difficultés ou de l'impossibilité de parler (trachéotomie, trachéostomie).…”

Section: Douleurs Postopératoires Précocesunclassified

Prise en charge des douleurs somatiques induites par les traitements des cancers des voies aéro-digestives supérieures : la douleur post-chirurgicale. Recommandation de la Société française d’oto-rhino-laryngologie et de chirurgie de la face et du cou

Blanchard

Bollet

Dreyer

et al. 2014

Annales françaises d'Oto-rhino-laryngologie et de Pathologie Ce

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Assessment of Postoperative Pain After Laryngeal Surgery for Cancer

Abstract: After laryngeal surgery for cancer, pain can reach high levels, particularly in the first hours following recovery. Analgesic administrations at fixed hours are not effective enough. Postoperative analgesic treatment should aim to prevent the high initial pain and be individually adapted.

Cited by 15 publications

References 22 publications

Analgesic efficacy and safety of intravenous paracetamol (acetaminophen) administered as a 2 g starting dose following third molar surgery

Analgesic efficacy and safety of intravenous paracetamol (acetaminophen) administered as a 2 g starting dose following third molar surgery

Dexmedetomidine in combination with sufentanil for postoperative analgesia after partial laryngectomy

Prise en charge des douleurs somatiques induites par les traitements des cancers des voies aéro-digestives supérieures : la douleur post-chirurgicale. Recommandation de la Société française d’oto-rhino-laryngologie et de chirurgie de la face et du cou

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