Assessment of postoperative analgesia after intraperitoneal instillation of lornoxicam in laparoscopic appendectomy: a randomized study

Abstract

Background: The laparoscopic surgeries though results in less postoperative pain it is not a pain-free procedure and early postoperative pain is the most dominant complaint which requires strong analgesia. This study assessed post-operative analgesia after intraperitoneal instillation of lornoxicam in laparoscopic appendicectomy.Methods: This single blind randomized controlled trial was done in a tertiary care Centre of Patna from January 2016 to December 2016. A total of 60 patients scheduled for laparoscopic appenticectomy were randomly assigned into two groups of 30 each (Group A and B) using computer generated random numbers. Patients in group A received intraperitoneal instillation of 8 mg lornoxicam (Diluted in 100 ml of normal saline) and in group B patients received 100 ml of intraperitoneal normal saline. During the post-operative period pain and requirement of analgesia were assessed.Results: The demographic characteristics, clinical presentation and preoperative evaluation for vitals was comparable in group A and B. The mean VAS score was significantly low in group A compared to group B at fourth, sixth, eight and twelfth hour interval (p<0.050). In patients with group B, the requirement of analgesia was high (53.33%) compared to group A (33.33%) (p=0.118).Conclusions: The intraperitoneal instillation of lornoxicam is simple analgesic technique that reduces the pain without adverse effects compared to normal saline.

The Relationship Of Anti-Inflammation Non Steroid Use Patterns With Side Effects In Patients Post Appendectomy At Jemursari Islamic Hospital

“…This drug has side effects on the gastrointestinal tract such as nausea, vomiting, dyspepsia, diarrhea to bloody diarrhea, and other symptoms of irritation to the gastric mucosa (Gunawan, 2016). This study agrees with research conducted by Amrullah and Utami (2016) (Kumar et al, 2018).…”