Assessment of peripheral blood flow using a pulse oximeter

Vegfors, M.; B, Tryggvason; Sjöberg, Folke; Lennmarken, C.

doi:10.1007/bf02832175

Cited by 11 publications

(5 citation statements)

References 12 publications

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“…When using PI to confirm the efficacy of a SGB, some factors should be taken into consideration. First, because body movements cause changes in the pulse oximetry AC/DC signal ratio22,23 before and after SGB the body posture of the patient should not be changed. The influence of the redistribution of body fluids, or changes in the way the sensor is positioned may affect the measurement of PI.…”

Section: Discussionmentioning

confidence: 99%

“…The influence of the redistribution of body fluids, or changes in the way the sensor is positioned may affect the measurement of PI. Additionally, applying pressure to the sensor may cause changes in blood flow in the skin microcirculation,22–25 and therefore, should be avoided. In conclusion, we found that continuous measurements of the PI using a pulse oximeter could be useful for determining the efficacy of SGB.…”

Section: Discussionmentioning

confidence: 99%

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Use of perfusion index from pulse oximetry to determine efficacy of stellate ganglion block

Yamazaki

Nishiyama²,

Suzuki³

2012

LRA

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BackgroundStellate ganglion block (SGB) is a widely used procedure for treatment of pain in the head and upper body, but the clinical signs used to verify the effectiveness of SGB can be ambiguous or variable in some patients. We observed the chronological changes in perfusion index (PI) from pulse oximetry to determine if these changes correlated with the clinical signs associated with an effective SGB. We hypothesized that PI could provide an easy method to assess the effectiveness of SGB.MethodWe compared the chronologies in PI on the treated and untreated sides of 21 patients in whom treatment by SGB was found to be effective. The SGB was performed by administering 6 mL of 1% mepivacaine. The effectiveness of the SGB was confirmed on the basis of clinical signs. Additionally, in two patients we tested whether increased PI on the treatment side correlated with increased microcirculation as measured by laser-Doppler blood flowmetry.ResultsOn the side treated by SGB, PI increased 61.4% in the earlobe and 60.5% from baseline values in the upper limbs, at 5 minutes after initiation of the procedure. Differences in PI before and after treatment were significant at both sites. No time-course increases in PI were found on the untreated side at either site. Following SGB, increases in PI correlated with increases in blood flow as measured by laser-Doppler flowmetry.ConclusionPI increased in the earlobe and upper limbs on the treated side of 21 patients who received an effective SGB but not on the untreated side. The positive correlations between changes in PI and both presence of clinical signs and changes in blood flow in the skin microcirculation indicate a sympatholytic effect, suggesting that the PI could be useful in determination of the efficacy of SGB.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Use of perfusion index from pulse oximetry to determine efficacy of stellate ganglion block

Yamazaki

Nishiyama²,

Suzuki³

2012

LRA

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“…11 ± 12 One of the limitations of physiologic investigation of female genital sexual arousal is quantitative assessment of the arousal response. Recent advances in the measurement of hemoglobin by laser oximetry 13 have facilitated quantitation of changes in blood¯ow in female genital (vaginal, labial, clitoral) tissues. We have employed this technology, along with laser Doppler¯owmetry, to assess the effect of pelvic nerve stimulation on genital tissue engorgement.…”

Section: Introductionmentioning

confidence: 99%

Sildenafil augments pelvic nerve‐mediated female genital sexual arousal in the anesthetized rabbit

et al. 2000

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The NO-cGMP pathway has been implicated in clitoral and vaginal smooth muscle relaxation based on previous immunochemical, biochemical and physiologic studies. There are limited data from in vivo studies demonstrating enhancement of the genital sexual arousal response by pharmacologic agents in¯uencing the NO-cGMP pathway. The goal of this study was to investigate if sildena®l, a phosphodiesterase type-5 inhibitor, facilitated female genital sexual arousal in an animal model in response to pelvic nerve stimulation (PNS).Using female New Zealand White rabbits, we measured the following parameters before, during and after PNS at 4, 16, and 32 Hz: a) hemoglobin concentration and oxygen saturation in female genital (vaginal, labial, clitoral) tissues by laser oximetry; b) clitoral blood¯ow by laser Doppler owmetry; c) vaginal luminal pressure by a balloon catheter pressure transducer; d) vaginal lubrication by tampon. Sildena®l was administered intravenously (0.21 m mgakg, 0.42 m mgakg, 2.1 m mgakg) to achieve a systemic concentration of 5, 10 and 50 nM, respectively. After 20 minutes, physiologic measurements were repeated.Sildena®l (50 nM) caused a signi®cant increase in genital oxyhemoglobin concentration and a signi®cant decrease in genital deoxyhemoglobin concentration. Sildena®l also increased the duration of response following PNS, relative to genital hemoglobin concentration and mean clitoral blood¯ow. Sildena®l caused a decrease in vaginal luminal pressure and resulted in an increase in vaginal lubrication.These data indicate that the NO-cGMP pathway is involved in the physiologic mechanism of female genital arousal and that sildena®l facilitates this response in an in vivo animal model.

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“…Vegfors et al 31 reported that spinal anesthesia increased the blood flow of the foot, confirmed by Doppler flowmetry. It resulted in increased pulse oximeter signal, amplitude, with increased temperature.…”

Section: Discussionmentioning

confidence: 87%

Usefulness of the perfusion index for monitoring the response to intravenous ketamine infusion therapy in patients with complex regional pain syndrome

et al. 2023

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Background This study was performed to compare the perfusion index (PI) between affected and unaffected limbs in patients with complex regional pain syndrome (CRPS); it also evaluated the usefulness of the PI for monitoring the response to intravenous ketamine infusion therapy in such patients. Methods In total, 46 patients with CRPS in one arm or leg were enrolled in this study. The PIs of the unaffected (PIControl) and affected (PICRPS) limbs were simultaneously evaluated before and after treatment. Results PICRPS was significantly lower than PIControl at all time points. The change in PI from immediately before to 30 min after intravenous ketamine infusion therapy (TBefore and T30 min, respectively) in the affected limb was significantly correlated with the change in visual analog pain scale (VAS) between the two time points (r = 0.646, p < 0.001). The area under the curve for the changes in VAS and PICRPS between TBefore and T30 min was 0.928. The optimal threshold value for the change in PICRPS between TBefore and T30 min, to distinguish responders with a ≥ 50‐point reduction in VAS score from nonresponders, was 22.60% with a sensitivity of 0.811 (95% CI: 0.774–0.848) and a specificity of 0.889 (95% CI: 0.848–0.930). Thirty‐one patients showed a ≥ 50‐point reduction in VAS score [67% (95% CI: 54%–80%)] and 15 patients showed a < 50‐point reduction in VAS score [33% (95% CI: 20%–46%)]. Thirty patients showed an increased PI ≥ 22.60% [65% (95% CI: 50%–78%)] and 16 patients showed an increased PI < 22.60% [35% (95% CI: 22%–50%)]. Twenty‐seven patients had a ≥ 50‐point reduction in VAS score and an increased PI ≥ 22.60% [59% (95% CI: 44%–74%)]. Eleven patients had shown a < 50‐point pain reduction in VAS score and increased PI < 22.60% [24% (95% CI: 13%–37%)]. Conclusion The PI significantly differed between affected and unaffected limbs in patients with CRPS. The PI may be useful for monitoring the response to intravenous ketamine therapy in patients with CRPS.

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Assessment of peripheral blood flow using a pulse oximeter

Cited by 11 publications

References 12 publications

Use of perfusion index from pulse oximetry to determine efficacy of stellate ganglion block

Use of perfusion index from pulse oximetry to determine efficacy of stellate ganglion block

Sildenafil augments pelvic nerve‐mediated female genital sexual arousal in the anesthetized rabbit

Usefulness of the perfusion index for monitoring the response to intravenous ketamine infusion therapy in patients with complex regional pain syndrome

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