Assessment of performance parameters for EPR dosimetry with tooth enamel

Wieser, A.; Fattibene, P.; Shishkina, E.A.; Иванов, Д.; Coste, V. De; Güttler, Andreas; Onori, S.

doi:10.1016/j.radmeas.2008.01.032

Cited by 31 publications

(23 citation statements)

References 18 publications

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“…The methodology suggested in Wieser et al (2008) was tested in sixteen laboratories. As a first approximation, varianve of EPR measurements was assumed to be constant and independent of dose.…”

Section: Discussionmentioning

confidence: 99%

“…A method for the evaluation of critical level and detection limit in EPR dosimetry with tooth enamel was suggested and tested in three laboratories, as described in Wieser et al (2008). The aims of the present inter-laboratory comparison were i) to share and disseminate the methodology suggested in Wieser et al (2008) among a large number of laboratories in order to find a common field of discussion, hopefully leading to the harmonization of the method; ii) to evaluate the applicability of this approach to a large number of laboratories.…”

Section: Introductionmentioning

confidence: 99%

“…As a preliminary analysis of the data, performance parameters were evaluated under the homoscedastic assumption. The calculation of the performance parameters under the heteroscedastic assumption (which applies better to EPR dosimetry with tooth enamel) requires the evaluation of an analytical model function of the variance in dependence on the absorbed dose (Wieser et al 2008). This further evaluation, as well an analysis of the correlation of the performance parameters with specific features of the measurement procedures was not within the scope of this paper and it will be developed in a future analysis.…”

Section: Introductionmentioning

confidence: 99%

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The 4th international comparison on EPR dosimetry with tooth enamel

Fattibene

Wieser

Adolfsson

et al. 2011

Radiation Measurements

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This paper presents the results of the 4th International Comparison of in vitro electron paramagnetic resonance dosimetry with tooth enamel, where the performance parameters of tooth enamel dosimetry methods were compared among sixteen laboratories from all over the world. The participating laboratories were asked to determine a calibration curve with a set of tooth enamel powder samples provided by the organizers. Nine molar teeth extracted following medical indication from German donors and collected between 1997 and 2007 were prepared and irradiated at the Helmholtz Zentrum München. Five out of six samples were irradiated at 0.1, 0.2, 0.5, 1.0 and 1.5 Gy air kerma; and one unirradiated sample was kept as control. The doses delivered to the individual samples were unknown to the participants, who were asked to measure each sample nine times, and to report the EPR signal response, the mass of aliquots measured, and the parameters of EPR signal acquisition and signal evaluation. Critical dose and detection limit were calculated by the organizers on the basis of the calibration-curve parameters obtained at every laboratory. For calibration curves obtained by measuring every calibration sample three times, the mean value of the detection limit was 205 mGy, ranging from 56 to 649 mGy. The participants were also invited to provide the signal response and the nominal dose of their current dose calibration curve (wherever available), the critical dose and detection limit of which were also calculated by the organizers..

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The 4th international comparison on EPR dosimetry with tooth enamel

Fattibene

Wieser

Adolfsson

et al. 2011

Radiation Measurements

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“…The results of investigations showed that each method possesses restrictions in its application for complex (external and internal) radiation exposure, especially for low-dose exposure. The application of these methods for the Techa River situation required additional work on improvement of methods performed recently in collaboration with European colleagues Fattibene et al 2006;Wieser et al 2008;Darroudi et al 2008;). Reliable estimates of cumulative anthropogenic dose in bricks of the old buildings in Metlino and Muslyumovo were obtained with use of the luminescent method (Jacob et al 2003;Bougrov et al 2009;Degteva et al 2008a;Ulanovsky et al 2009).…”

Section: Validation Of External Dosesmentioning

confidence: 99%

Individual Dose Calculations with Use of the Revised Techa River Dosimetry System TRDS-2009D

Shagina¹,

Толстых²,

Vorobiova³

et al. 2009

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“…For table 27, the angular coefficient (slope) was normalized by the gain used in EMR measurement of each compound; as for the dose-response curve analysis, it was not considered. Also, the detection limit presented was calculated by the method described previously in Wieser et al (2008), also applied by Fattibene et al (2011). Analyzing the linear fittings, lithium formate, by far, has the higher sensitivity, followed by sodium formate and sodium dithionite.…”

Section: Resultsmentioning

confidence: 99%

Campos pequenos de radiação e materiais alternativos em dosimetria com espectroscopia de ressonância magnética eletrônica

Rech¹

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Rech AB. Small radiation field and alternative materials in dosimetry with electron magnetic resonance spectroscopy [thesis]. Ribeirão Preto: Universidade de São Paulo, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto; 2017.To keep up with advances in radiotherapy, dosimetric systems need improvement to meet the standards established for treatment accuracy; simultaneously, radioactive exposure goes beyond clinical use, and the detection in unforeseen scenarios is of interest too. Electron magnetic resonance spectroscopy (EMR) can detect paramagnetic centers created in materials exposed to radiation, relating spectral response with absorbed dose, thus performing nondestructively dosimetry, by keeping the information after the readout. After standardization of alanine as a high dose detector and the applicability in clinical studies, difficulties allowed the investigation of other EMR dosimetry materials; on the other hand, classifying compounds that are present daily and with the possibility of tissue equivalence is another stimulus for the expansion of alternative materials analysis. The development of this thesis is between two distinct but interconnected topics; first minidosimeters are presented for small field dosimetry, with a clinical approach, and the investigation of alternative materials, both topics applied in EMR dosimetry. Concerning the minidosimeters, some pellets' aspects are studied, a new concept of detector, called EPResize®; and a stereotactic radiosurgery end-to-end audit are presented; about alternative materials research, more than 20 compounds were studied, based on ammonium, lithium, potassium and sodium. The results showed that the difficulties in determining the dose with small fields in a clinical dose range is an issue that still needs much attention and adequacy of the dosimetric systems, in order to extract the greatest possible sensitivity, with the need to employ parameters and methods of analysis besides the daily used; several materials were adequate for EMR dosimetry, such as ammonium sulfate, sodium formate, sodium dithionate, sodium citrate and different sulfites, which, even when not satisfying clinical aspects, are alternatives for control and determination of doses in other scenarios. The ability to perform clinical dosimetry with RME and the standardization of this system allow the improvement of treatments accuracy, and the availability of a greater variety of EMR dosimetry materials facilitates the need for dose mapping unforeseen cases.

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Assessment of performance parameters for EPR dosimetry with tooth enamel

Cited by 31 publications

References 18 publications

The 4th international comparison on EPR dosimetry with tooth enamel

The 4th international comparison on EPR dosimetry with tooth enamel

Individual Dose Calculations with Use of the Revised Techa River Dosimetry System TRDS-2009D

Campos pequenos de radiação e materiais alternativos em dosimetria com espectroscopia de ressonância magnética eletrônica

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