Assessment of patterns of dyslipidaemia amongst hypertensive patients

Abstract

Background: Abnormalities in serum lipid and lipoprotein levels (Dyslipidaemia) are recognized as major modifiable cardiovascular disease (CVD) risk factors and have been identified as independent risk factors for essential hypertension giving rise to the term dyslipidemic hypertension. The present study was conducted to assess patterns of dyslipidaemia amongst hypertensive patients. Materials and Methods: 76 hypertensive patients of both genders were recruited. Group I consisted of hypertensive patients and group II had healthy control. Systolic (SBP) and diastolic (DBP) blood pressures, Body mass index (BMI), Fasting blood glucose and fasting serum lipid profile was recorded. Results: Group I had 40 males and 36 females and group II had 38 males and 38 females. In group I and group II, SBP (mm Hg) was 162.4 and 116.4, DBP (mm Hg) was 98.4 and 70.2, BMI (kg/m 2 ) was 28.6 and 26.2, WC (cm) was 96.4 and 90.4, WHR was 0.98 and 0.94, FBS (mmol/L) was 5.1 and 4.6, TG was 1.24 and 1.10, HDL-c was 1.26 and 1.24, LDL-c was 3.01 and 2.42 and TC was 4.82 and 4.15 respectively. Elevated TC (≥5.2 mmol/L) was seen in 34% and 7.5%, elevated TG (≥1.7 mmol/L) in 7% and 1%, elevated LDL-C (≥3.4 mmol/L) in 29% and 6.2%, low HDL-C (<1.04 mmol/L) in 22% and 15%, no lipid abnormality in 46% and 72%, one lipid abnormality in 20% and 16% and >2 lipid abnormality in 24% and 12% in group I and II respectively. Conclusion: There was high patterns of dyslipidemia amongst hypertensive patients as compared to healthy subjects.