Assessment of patent foramen ovale in carcinoid heart disease

Mansencal, Nicolas; Mitry, Emmanuel; Forissier, J.-F.; Martin, F.; Redheuil, Alban; Lepère, Céline; Farcot, Jean-Christian; Joseph, Thierry; Lacombe, Pascal; Rougier, Philippe; Dubourg, Olivier

doi:10.1016/j.ahj.2006.02.019

Cited by 43 publications

(41 citation statements)

References 24 publications

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“…Compared with the right side of the heart, the left-sided valves are rarely affected because of the pulmonary metabolism and deactivation of the hormonal substances [18] . However, left-sided involvement is more frequent in patients with patent foramen ovale (76-88%) [26] , which appears to be more common in patients with CS and CHD compared with the general population (up to 41% in patients with CS and up to 59% in those with CHD) [27] .…”

Section: Pathophysiologymentioning

confidence: 99%

Carcinoid Heart Disease: From Pathophysiology to Treatment - ‘Something in the Way It Moves'

2015

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Carcinoid heart disease (CHD) is a rare cardiac manifestation occurring in patients with advanced neuroendocrine tumours and the carcinoid syndrome, usually involving the right-sided heart valves and eventually leading to right heart failure. The pathophysiology of CHD is still obscure and believed to be multifactorial, as a variety of vasoactive substances secreted by the tumour appear to be involved. The management of patients with CHD is complex, as both the systemic malignant disease and the heart involvement have to be addressed. Timely diagnosis and early surgical treatment in appropriately selected patients are of outmost importance, as CHD is associated with increased morbidity and mortality. Valve replacement surgery alleviates right heart failure and may also contribute to improved survival. In the present study we have comprehensively reviewed the existing literature to date, mainly focusing on the pathophysiology of CHD. Other aspects of CHD (such as the clinical presentation, diagnostic tools and therapeutic approach) are addressed in brief.

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Section: Pathophysiologymentioning

confidence: 99%

Carcinoid Heart Disease: From Pathophysiology to Treatment - ‘Something in the Way It Moves'

2015

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“…More recently, the coincidence of a patent foramen ovale (PFO) has been described together with CHD [118,119] , and may increase the chance of left-sided heart lesions; its closure has also improved functional outcome in CHD patients. A patent foramen ovale should therefore be ruled out in clinically progressing CHD and prior to cardiac surgery.…”

Section: Minimal Consensus Statement On Palliative Surgerymentioning

confidence: 99%

ENETS Consensus Guidelines for the Management of Patients with Neuroendocrine Neoplasms from the Jejuno-Ileum and the Appendix Including Goblet Cell Carcinomas

et al. 2012

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“…More recently, the coexistence of a patent foramen ovale (PFO) has been described together with CHD [121,122,123], and it may increase the chance of left-sided heart lesions; its closure has also improved functional outcome in CHD patients. A PFO should therefore be ruled out in clinically progressing CHD and prior to cardiac surgery.…”

Section: Chd (Hedinger Syndrome)mentioning

confidence: 99%

ENETS Consensus Guidelines Update for Neuroendocrine Neoplasms of the Jejunum and Ileum

et al. 2016

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Assessment of patent foramen ovale in carcinoid heart disease

Cited by 43 publications

References 24 publications

Carcinoid Heart Disease: From Pathophysiology to Treatment - ‘Something in the Way It Moves'

Carcinoid Heart Disease: From Pathophysiology to Treatment - ‘Something in the Way It Moves'

ENETS Consensus Guidelines for the Management of Patients with Neuroendocrine Neoplasms from the Jejuno-Ileum and the Appendix Including Goblet Cell Carcinomas

ENETS Consensus Guidelines Update for Neuroendocrine Neoplasms of the Jejunum and Ileum

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