Assessment of Nutrient Intake and Dietary Quality of Korean Adults in Metabolic Syndrome Patients According to Taking Medical Care: Based on the 2017 Korea National Health and Nutrition Examination Survey

Lee, Juhee; Choi, Kyung-Suk

doi:10.5720/kjcn.2022.27.4.321

Cited by 4 publications

(2 citation statements)

References 24 publications

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“…It increases the probability of diabetes by about five times and that of cardiovascular disease by about two times, and individuals with MetS have a mortality rate four times higher than that of the general population. The prevalence of MetS is about 31.4% in the United States and about 20% in Korea, where it is increasing ( Lee and Choi, 2022 ). In addition, MetS is strongly associated with fatty liver, obstructive sleep apnea, and various cancers.…”

Section: Introductionmentioning

confidence: 99%

Identification of shared genetic risks underlying metabolic syndrome and its related traits in the Korean population

Kim,

Cho

2024

Front. Genet.

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Introduction: Observational studies have demonstrated strong correlations between metabolic syndrome (MetS) and its related traits. To gain insight into the genetic architecture and molecular mechanism of MetS, we investigated the shared genetic basis of MetS and its related traits and further tested their causal relationships.Methods: Using summary statistics from genome-wide association analyses of about 72,000 subjects from the Korean Genome and Epidemiological Study (KoGES), we conducted genome-wide multi-trait analyses to quantify the overall genetic correlation and Mendelian randomization analyses to infer the causal relationships between traits of interest.Results: Genetic correlation analyses revealed a significant correlation of MetS with its related traits, such as obesity traits (body mass index and waist circumference), lipid traits (triglyceride and high-density lipoprotein cholesterol), glycemic traits (fasting plasma glucose and hemoglobin A1C), and blood pressure (systolic and diastolic). Mendelian randomization analyses further demonstrated that the MetS-related traits showing significant overall genetic correlation with MetS could be genetically determined risk factors for MetS.Discussion: Our study suggests a shared genetic basis of MetS and its related traits and provides novel insights into the biological mechanisms underlying these complex traits. Our findings further inform public health interventions by supporting the important role of the management of metabolic risk factors such as obesity, unhealthy lipid profiles, diabetes, and high blood pressure in the prevention of MetS.

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Section: Introductionmentioning

confidence: 99%

Identification of shared genetic risks underlying metabolic syndrome and its related traits in the Korean population

Kim,

Cho

2024

Front. Genet.

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“…Ceylon cinnamon (Cinnamomum zeylanicum) is native to Sri Lanka [5]. The area is famous for many widely utilized plant products, and it is also known for its biologically active substances [6]. Cinnamon has many health benefits, including anti-inflammatory properties, blood-glucose regulation, and anti-cardiovascular properties.…”

Section: Introductionmentioning

confidence: 99%

Effects of Cinnamon (Cinnamomum zeylanicum) Extract on Adipocyte Differentiation in 3T3-L1 Cells and Lipid Accumulation in Mice Fed a High-Fat Diet

Oh,

Ahn,

Zhou

et al. 2023

Nutrients

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Flavonoids and phenolic acid are two of the rich polyphenols found in cinnamon (Cinnamomum zeylanicum). The effects of cinnamon extract on the inhibition of adipocyte differentiation in 3T3-L1 fibroblast cells and prohibitory lipid accumulation in male mice fed a high-fat diet were examined. Upon treating 3T3-L1 cells with cinnamon for 3 days, the cinnamon inhibited lipid accumulation and increased gene expression levels, such as those of adiponectin and leptin. In in vivo experiments, mice were randomized into four groups after a one-week acclimation period, as follows: normal diet, normal diet + 1% cinnamon extract, high-fat diet, and high-fat diet + 1% cinnamon extract. After 14 weeks of supplementation, we found that cinnamon extract increased the expression of lipolysis-related proteins, such as AMPK, p-ACC, and CPT-1, and reduced the expression of lipid-synthesis-related proteins, such as SREBP-1c and FAS, in liver tissue. Our results show that cinnamon extract may exhibit anti-obesity effects via the inhibition of lipid synthesis and adipogenesis and the induction of lipolysis in both 3T3-L1 fibroblast cells and mice fed a high-fat diet. Accordingly, cinnamon extract may have potential anti-obesity effects.

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Distribution of the Metabolic Syndrome by Obesity and Health Behavior Based on the Eighth KNHANES at 2019

Chong

Han

2022

JKFN

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This study examined the distribution of subjects in three groups, namely normal (0), caution (1∼2), and metabolic syndrome (MS) (≥3), based on the number of diagnostic criteria of metabolic syndrome. The data was sourced from the eighth (2019) Korea National Health and Nutrition Examination Survey (KNHANES). Elevated blood pressure occurred most frequently in caution group and three-combined cases were the most frequent in MS group. In males, older subjects and those with lower education levels were in higher numbers in MS group. Higher frequencies of eating breakfast and eating out decreased the probability of being in MS group, and smoking increased this probability in total. Males consuming alcohol more than five times per month showed the highest probability of belonging to MS group, but in females, this was true of those drinking less than once a month. An increase in body mass index and a higher waist circumference increased the probability of being in MS group in both males and females. Subjects with higher blood pressure, blood glucose, and triglyceride, and lower HDL-cholesterol showed a higher probability of being in MS group. The intake of vegetables was the highest in MS group for both males and females and that of fruits was the highest for females in caution group. The intakes of meats and beverages were the lowest in MS group. In conclusion, health behavior and food intake are related to MS and therefore the improvement in these behaviors is needed to reduce the risk of MS.

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Assessment of Nutrient Intake and Dietary Quality of Korean Adults in Metabolic Syndrome Patients According to Taking Medical Care: Based on the 2017 Korea National Health and Nutrition Examination Survey

Cited by 4 publications

References 24 publications

Identification of shared genetic risks underlying metabolic syndrome and its related traits in the Korean population

Identification of shared genetic risks underlying metabolic syndrome and its related traits in the Korean population

Effects of Cinnamon (Cinnamomum zeylanicum) Extract on Adipocyte Differentiation in 3T3-L1 Cells and Lipid Accumulation in Mice Fed a High-Fat Diet

Distribution of the Metabolic Syndrome by Obesity and Health Behavior Based on the Eighth KNHANES at 2019

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