2022
DOI: 10.1093/ofid/ofac279
|View full text |Cite
|
Sign up to set email alerts
|

Assessment of Noninvasive Markers of Steatosis and Liver Fibrosis in Human Immunodeficiency Virus-Monoinfected Patients on Stable Antiretroviral Regimens

Abstract: Background Nonalcoholic fatty liver disease (NAFLD) is a major non–AIDS-defining condition for persons living with HIV (PLWHIV). We aimed to validate noninvasive tests for the diagnosis of NAFLD in PLWHIV. Methods Cross-sectional study of PLWHIV on stable ART with persistently elevated transaminases and no known liver disease. The AUROC was calculated to compare the diagnostic accuracy of liver biopsy with abdominal ultrasoun… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

0
2
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
4
1

Relationship

0
5

Authors

Journals

citations
Cited by 8 publications
(2 citation statements)
references
References 32 publications
0
2
0
Order By: Relevance
“…[18] and included two additional references that fulfilled the review's inclusion/exclusion criteria. Twenty‐four articles ( n = 24) were finally included [40–63]. Table S2 in the Supplementary File lists a number of key articles that were excluded from the present SR (reasons for exclusion are provided in the Table).…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…[18] and included two additional references that fulfilled the review's inclusion/exclusion criteria. Twenty‐four articles ( n = 24) were finally included [40–63]. Table S2 in the Supplementary File lists a number of key articles that were excluded from the present SR (reasons for exclusion are provided in the Table).…”
Section: Resultsmentioning
confidence: 99%
“…The pooled prevalence from the two studies with a CAP threshold for NAFLD diagnosis of ≥238 dB/m was 34% (95% CI: 29-38%) (heterogeneity not estimable). One study used a CAP threshold of ≥251 dB/m, finding a NAFLD prevalence of 34% (95% CI: [25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44]. Another one that defined NAFLD as a CAP≥275 dB/m found a 34% (95% CI: 25-44) NAFLD prevalence (heterogeneity not estimable).…”
Section: Subgroup Analyses (Ma Of Prevalence)mentioning
confidence: 99%