Assessment of newborn screening in the public health system of a municipality in northern Rio Grande do Sul

Abstract

Introduction: Newborn screening allows the screening of diseases that are still in the asymptomatic period and whose early diagnosis and treatment are associated with reduced infant morbidity and mortality. The aim of this study was to evaluate the public National Newborn Screening Program in the municipality of Carazinho, state of Rio Grande do Sul (RS), Brazil. Methods: This was a population-based, retrospective, descriptive study. We collected and transcribed data from a database of the Carazinho municipal laboratory, which is affiliated with the referral center for newborn screening in RS. The records of all individuals undergoing newborn screening from 2005 to 2010 were reviewed, and information was collected on the program coverage, time elapsed between birth and screening (first collection), and test results. Results: The program had a coverage of 75.5%. One suspected case of phenylketonuria, three suspected cases of congenital hypothyroidism and no suspected cases of hemoglobinopathy were identified. In addition, there were 18 positive results for hemoglobin S heterozygosity, five for hemoglobin D heterozygosity, two for hemoglobin C heterozygosity, and one for a rare variant hemoglobin. When analyzing the newborn's age at the time of blood collection, it was observed that 63.1% were within the recommended age range. Conclusions: Our findings suggest the need for optimization of public newborn screening in the evaluated municipality. The strategies to be adopted should include education of the population and especially of managers and health professionals about the importance of newborn screening.

Universal neonatal hearing screening program at a university hospital: an analysis using quality indicators

“…Seven out of 20 NBs were identified with some type of HL (one to two per 1,000 live births), corroborating the findings of another study 9 . Childhood HL prevalence rates can reach three per 1,000 live births, which is a high incidence when compared with other diseases detectable with neonatal screenings -such as the genetic and metabolic ones detected with the heel prick, whose results indicate one patient with one of these diseases per 10,000 live births 25 . Early HL identification influences both the HA fitting process and the referral for a cochlear implant.…”

Avaliação de indicadores de qualidade do programa de triagem neonatal do Amazonas entre 2013 e 2016

“…No estudo de Ribeirão Preto -SP observou-se mediana de idade de inicio de tratamento para PKU de 20 dias(27). Nos estudos de Sergipe e Tocantins esse indicador não foi abordado (15)(34), assim como no recente estudo sobre o programa de triagem neonatal em Carazinho-RS(14). Na Turquia, em 2017, foi observado na província de Adana uma mediana de idade para primeira consulta de pacientes com HCde 19,8 dias de vida(36).…”