Assessment of neuropsychological changes in patients with arteriovenous malformation (AVM) after radiosurgery

Cognitive Effects of Chemotherapy and/or Cranial Irradiation in Adults

“…In a normally distributed population, one would expect 15.8% aberrant results [72]. No significant differences were found for cognitive deficits at all, cognitive impairment rate, and single cognitive domains, if specified, when chemotherapy, irradiation and radiochemotherapy were compared (although knowing that a direct statistical comparison as done for the purpose of this review is not absolutely valid due to extremely different criteria for cognitive impairment).…”

“…The characteristics of the 24 trials are shown in Appendix B. Four trials were excluded from the analyses for one or more of the following reasons: the trial was published again with an extended sample size and the same results, the tested cognitive domains were not specified, or no objective cognitive assessment was used [4,38,69,72]. Thus, the results are based on 20 trials with 732 patients.…”

Neuropsychological Features of Lesion-related Epilepsy in Adults: An Overview

“…While some have observed deficits in general intellectual functions (e.g., von Overbeeke et al 1987;Wenz et al 1998), others have determined that the AVM had no overall influence on patients' global intellectual level (Stabell and Nornes 1994;Waltimo and Putkonen 1974). Deficits in the cognitive functioning of patients with AVMs in various cortical locations, often in the context of a bleed and seizure history, have been reported in many neuropsychological domains, including verbal and visual memory (e.g., Buklina 2005, Mahalick et al 1991Stabell and Nornes 1994;Wenz et al 1998) attention (Wenz et al 1998), language (e.g., Conley et al 1980;Waltimo and Putkonen 1974), visuoconstructional abilities and perceptual/organizational skills (e.g., Buklina 2005;Stabell and Nornes 1994;von Overbeeke et al 1987), fluency (Mahalick et al 1991;Stabell and Nornes, 1994), rapid set-shifting (Stabell and Nornes 1994), and motor speed and finger dexterity (Conley et al 1980;Mahalick et al 1991). Von Overbeeke et al (1987) reported visuoperceptual problems, simultaneous agnosia, alexia, and dyscalculia, as well as memory deficits, in a patient with AVM in the dominant temperoparietoccipital region with a history of seizures but no hemorrhage.…”

Acute neurocognitive impairment during cranial radiation therapy in patients with intracranial tumors

“…We have previously reported impaired performance in the verbal memory domain after the first fraction of fractionated stereotactic radiotherapy (FSRT) in patients with base of skull meningiomas [42]. In contrast, patients undergoing hyperfractionated total body irradiation (TBI) before autologous bone marrow/peripheral blood stem cell transplantation or patients undergoing radiosurgery for arteriovenous malformations (AVMs) showed no verbal memory impairment [43,[47][48][49].…”