Assessment of Neonatal Respiratory Distress Incidences with Causes, Mortality and Morbidity in a Tertiary Care Hospital

Baloch, Kanwal; Mugheri, Delijan; Soomro, Abdul Majeed; Bhatti, Wasim Sarwar; Khan, Muhammad Junaid; Wassan, Shafi Muhammad; Usman, Shumaila; Nisar, Uzair; Malhani, Waseem Abbas; Baloch, Nadeem; Mangi, Altaf Ali; Lashari, Saika; Arbani, Rashid Ali; Alolyan, Sultan Othman; Arain, Shumaila Parveen; Alshahrani, Sultan M.

doi:10.9734/jpri/2020/v32i2730849

Cited by 3 publications

(2 citation statements)

References 6 publications

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“…24 Some researchers have depicted sepsis to be the most common cause of death in neonates with respiratory distress but we did not witness that. 25,26 This study had some limitations as well. Single center study setting and a relatively modest sample size reduce the generalisability of our findings.…”

Section: Discussionmentioning

confidence: 97%

Spectrum of respiratory distress and outcome in neonates admitted in National Institute of Child Health, Karachi, Pakistan.

Lachhman Singh Rajput,

Mashal Khan

2024

TPMJ

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Objective: To find out the spectrum of respiratory distress and outcome in neonates admitted to Neonatal Intensive care unit (NICU) of National Institute of Child Health (NICH), Karachi, Pakistan. Study Design: Cross-sectional study. Setting: NICU of NICH, Karachi, Pakistan. Period: June 2022 to May 2023. Methods: We analyzed 148 neonates of either gender presenting with respiratory distress. At the time of enrollment, demographic and clinical information was noted in all neonates along with detailed maternal history. Relevant laboratory and radiological studies were performed. Final outcomes were recorded in terms of discharged, expired or referred. Results: In a total of 148 neonates, 96 (64.9%) were boys. The mean age was 4.04±5.65 days. Tachypnea, nasal flaring, intercostal recession, subcostal recession, grunting, and cyanosis 148 (100%), 146 (98.6%), 138 (93.2%), 133 (89.9%), 97 (65.5%), and 83 (56.1%) were the most frequent clinical presentations among neonates with respiratory distress. The most frequent causes behind respiratory distress were noted to be respiratory distress syndrome, sepsis, and meconium staining of labour in 31 (20.9%), 25 (16.9%), and 24 (16.2%) neonates. Mortality was observed in 21 (14.2%) neonates. Significant association of neonates presenting with congenital pneumonia (p=0.048), or congenital anomalies (p<0.001) were found to with poor outcomes. Mechanical ventilation was found to have significant relationship with poor outcomes (p<0.001). Conclusion: Tachypnea, Nasal flaring, intercostal and subcostal recessions, grunting, and cyanosis were the primary clinical presentations among the neonates with respiratory distress. Congenital pneumonia, and congenital anomalies emerged as key predictors of poor outcomes.

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Section: Discussionmentioning

confidence: 97%

Spectrum of respiratory distress and outcome in neonates admitted in National Institute of Child Health, Karachi, Pakistan.

Lachhman Singh Rajput,

Mashal Khan

2024

TPMJ

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“…It is still unknown how often respiratory distress syndrome (RDS) occurs in newborns. This issue, which has started to get substantial attention in the medical community in the last 15-20 years, [14][15][16][17] has been the topic of numerous epidemiological studies. Intellectual disability or cerebral palsy, cardiovascular issues, and a higher newborn death rate are all effects of RDS.…”

Section: Introductionmentioning

confidence: 99%

Low-Cost SpO2 Integrated Neonatal CPAP Device for Low Resource Setting

Dawud¹,

Abagaro²

2023

MDER

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Introduction More than 60% of preterm births take place in South Asia and sub-Saharan Africa, making prematurity a primary cause of neonatal mortality. Even though continuous positive airway pressure (CPAP) is a popular treatment for respiratory distress syndrome (RDS) and is safe, practicable, and efficient for use in LMICs, it is crucial to ensure that neonates receive the full benefits of the therapy by monitoring their blood oxygen level. Methods A centrifugal fan, power source, control system, and sensors are all included in our design. A centrifugal fan was created to provide air at positive pressure in the range of approximately 4 cmH2O to 20 cmH2O utilizing revolving blades (impeller), a DC motor, and a fixed component. The control unit contains a microcontroller to handle sensor data. The proportional-integral (PI) controller board’s external potentiometer is used to set the pressure level. Results To ascertain whether the prototype satisfies the design requirements, it was constructed and put through several iterations and testing. The proposed device’s prototype was tested for accuracy, affordability, and usability. The centrifugal fan speed measurement was accurate to within 94.5%, while the oxygen concentration sensor reading was accurate to within 98.5%. Conclusion The design investigates viability of a straightforward, inexpensive, portable SpO2 integrated neonatal CPAP device for use in the delivery room in low-resource countries and to evaluates methods for measuring flows during CPAP treatment by monitoring the level of oxygen in the blood and pressure level delivered by the device using the lowest and safest setting that yields useful results.

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Global, Regional and National Trends in the Burden of Neonatal Respiratory Failure and essentials of its diagnosis and management from 1992 to 2022: a scoping review

Tochie,

Sibetcheu,

Arrey-Ebot

et al. 2023

Eur J Pediatr

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Assessment of Neonatal Respiratory Distress Incidences with Causes, Mortality and Morbidity in a Tertiary Care Hospital

Cited by 3 publications

References 6 publications

Spectrum of respiratory distress and outcome in neonates admitted in National Institute of Child Health, Karachi, Pakistan.

Spectrum of respiratory distress and outcome in neonates admitted in National Institute of Child Health, Karachi, Pakistan.

Low-Cost SpO2 Integrated Neonatal CPAP Device for Low Resource Setting

Global, Regional and National Trends in the Burden of Neonatal Respiratory Failure and essentials of its diagnosis and management from 1992 to 2022: a scoping review

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