Assessment of myocardial involvement using cardiac troponin‐I and echocardiography in rheumatic carditis in İzmir, Turkey

Tavli, Vedide; Canbal, Abdullah; Şaylan, Berna; Sarıtaş, Türkay; Meşe, Timur; Atlıhan, Füsun

doi:10.1111/j.1442-200x.2007.02511.x

Cited by 7 publications

(5 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our results are in agreement with Tavli et al .,[13] who showed that the level of cTnI is not elevated in acute rheumatic fever in children with and without carditis. In addition, they failed to show any echocardiographic signs of myocardial involvement in their study on rheumatic fever in children.…”

Section: Discussionsupporting

confidence: 94%

Myocardial involvement in the hemodynamic abnormalities associated with acute rheumatic fever

Nasr¹,

Mesbah²,

Saad³

2010

Journal of Cardiovascular Disease Research

View full text Add to dashboard Cite

Background and Aim:Rheumatic fever is still a common cause of acquired heart disease in children and young adult in many developing countries. The aim was to investigate the role of myocardial involvement in the hemodynamic changes in patients with acute rheumatic fever using cardiac troponin assay and echocardiography. Design: A prospective cohort study was designed.Patients and Methods:Thirty-four children with acute rheumatic fever, 20 with carditis, and 14 without carditis. Level of cardiac troponin T (cTnT) and echocardiographic measurement of left ventricular function were the main outcome measure.Results:The level of cardiac troponin in children with carditis was 0.051 ± 0.01 ng/dL, and it was 0.039 ± 0.02 ng/dL in those without carditis. The difference is not significant. In addition, there was no significant difference between the children with carditis and those without carditis regarding left ventricular ejection and shortening fractions.Conclusion:There are no significant echocardiographic measurements abnormalities or cTnT levels elevation suggesting clinically relevant hemodynamic abnormalities due to myocardial involvement during acute rheumatic fever.

show abstract

Section: Discussionsupporting

confidence: 94%

Myocardial involvement in the hemodynamic abnormalities associated with acute rheumatic fever

Nasr¹,

Mesbah²,

Saad³

2010

Journal of Cardiovascular Disease Research

View full text Add to dashboard Cite

show abstract

“…In agreement with Gupta et al [33], Oran et al [34], Tavli et al [26] and Cunningham [35], insignificant difference was found in cTnI levels between ARF children with arthritis and with carditis as compared to healthy controls. However, the absence of elevated cTnI throughout the course of ARF in particular during active carditis may be related to insignificant cardiomyocyte injury as reported by Oran et al [34], Gupta et al [33], Williams et al [36] and Kamblock et al [37].…”

Section: Discussionsupporting

confidence: 87%

“…Regarding the values of ASOT, ESR and CRP, insignificant differences between the three subgroups of ARF were in agreement with Alehan et al [23]; El Amrousy et al [24]; Roodpeyma et al [25] and Tavli et al [26]. Their prospective studies were performed on patients with acute rheumatic valvular disease using echocardiography and cTnI in order to detect myocardial involvement.…”

Section: Discussionsupporting

confidence: 81%

Clinical significance of sialic acid in acute rheumatic fever with and without carditis

Ibrahim¹,

Mansour²,

Ali³

et al. 2012

J Exp Integr Med

View full text Add to dashboard Cite

Objective: In Egypt, acute rheumatic fever (ARF) is the most common cause of acquired heart disease. ARF is a clinical syndrome without a specific diagnostic test or single pathognomonic feature, so the aim of this study is to investigate the utility of using serum total sialic acid (TSA) in differentiation between children suffering from ARF with and without carditis. Methods: In the present study, 62 children were divided into three groups: first group, 16 healthy children; second group, 20 patients suffering from chronic rheumatic heart disease (RHD); and third group, 26 patients suffering from ARF, subdivided into three subgroups as (A) 10 patients suffering from arthritis without carditis, (B) 10 patients with carditis but without congestive heart failure (CHF), and (C) 6 patients with carditis and CHF. Antistreptolysin O titre (ASOT) by latex agglutination test, erythrocyte sedimentation rate (ESR) by Westergren method, C-reactive protein (CRP) by turbidimetric immunoassay method, lactate dehydrogenase (LDH) activity by kinetic method, immunoglobulin levels by radial immunodifussion assay (RID), cardiac troponin I (cTnI) by ELISA test kit and TSA by diphenylamine (DPA) method were performed. Results: Significant elevated values of ESR, CRP, LDH, IgG and IgA were obtained in ARF as compared to both control and RHD groups; significant values of IgM were found between B and C as compared to control and RHD groups; cTnI showed insignificant difference between all groups; values of TSA showed highly significant difference between ARF as compared to both control and RHD groups as well as between RHD and control groups; significant difference was found between B and C groups as compared to group A. Conclusion: The results of the present study point out the possibility that the levels of TSA could be of help in differentiation between ARF patients with and without carditis. [J Exp Integr Med 2012; 2(4): 305-311

show abstract

“…Hence, many countries have proposed their own echocardiographic parameters in order not to underdiagnose subclinical or latent silent carditis. [6][7][8] However, there are no available data regarding left ventricular (LV) dyssynchrony in children with ARF.…”

Section: Introductionmentioning

confidence: 99%

“…Rheumatic carditis may be mild and can evolve over weeks to months and may course without clinical manifestation. Hence, many countries have proposed their own echocardiographic parameters in order not to underdiagnose subclinical or latent silent carditis . However, there are no available data regarding left ventricular (LV) dyssynchrony in children with ARF.…”

Section: Introductionmentioning

confidence: 99%

Ventricular dyssynchrony as a marker of latent carditis in children with acute rheumatic fever: A tissue Doppler imaging

2017

View full text Add to dashboard Cite

show abstract

Assessment of myocardial involvement using cardiac troponin‐I and echocardiography in rheumatic carditis in İzmir, Turkey

Abstract: The present results indicate the absence of myocardial involvement in acute rheumatic carditis without congestive heart failure.

Cited by 7 publications

References 24 publications

Myocardial involvement in the hemodynamic abnormalities associated with acute rheumatic fever

Myocardial involvement in the hemodynamic abnormalities associated with acute rheumatic fever

Clinical significance of sialic acid in acute rheumatic fever with and without carditis

Ventricular dyssynchrony as a marker of latent carditis in children with acute rheumatic fever: A tissue Doppler imaging

Contact Info

Product

Resources

About