In this work, the land snail, Monacha cartusiana, was studied to assess the deadly toxic activity of two pesticides (lambda and methomyl) on this snail in vitro, utilizing contact and dipping techniques. The results revealed that methomyl was more effective against snails compared with lambda in both methods of treatment. However, the contact application strategy resulted in greater death rates than the poison dipping studies. Accordingly, the mortality rate was increased by increasing concentration, with contact technique which recorded 96.3% and 69.99(15.1)% deaths by dipping way on concentration 3%. For this reason, the percent Lethal Concentration fifty (LC50) was 1.30% for one day and 1.67% for seven days for methomyl by contact and dipping techniques, respectively. On the other hand, the LC50 for lambda pesticide was achieved at 1.45% by contact method but was 7.51% by using the dipping application within ten days. As a result, mortality was greater after contact application than after dipping, and methomyl was disclosed to be more poisonous than lambda as a molluscicide.