Assessment of LVEF using a new 16-segment wall motion score in echocardiography

Lebeau, R; Serri, Karim; Lorenzo, Maria Di; Sauvé, Claude; Le, Van Hoai Viet; Soulières, Vicky; El-Rayes, Malak; Pagé, M. Gabrielle; Zaïani, Chimène; Garot, Jérôme; Poulin, Frédéric

doi:10.1530/erp-18-0006

Cited by 14 publications

(12 citation statements)

References 27 publications

(35 reference statements)

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“… 21 Two readers classified segmental wall motion using the following score: (1) normal; (2) hypokinetic; (3) akinetic; and (4) dyskinetic. Imaging data were analysed and WMS 22 was calculated as the average value of the studied segments. Myocardial function was assessed by evaluating the deformation of the myocardium using 2D STE and endocardial borders were detected at 2D end-systole.…”

Section: Methodsmentioning

confidence: 99%

Coronary-specific quantification of myocardial deformation by strain echocardiography may disclose the culprit vessel in patients with non-ST-segment elevation acute coronary syndrome

Guaricci¹,

Chiarello²,

Gherbesi

et al. 2022

European Heart Journal Open

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Aims To compare the diagnostic accuracy of speckle tracking echocardiography (STE) technique using territorial longitudinal strain (TLS) for the detection of culprit vessel vs. vessel-specific wall motion score index (WMSI) in non-ST segment elevation-acute coronary syndrome (NSTE-ACS) patients scheduled for invasive coronary angiography (ICA). Methods and Results One-hundred-eighty-three patients (mean age: 66±12 years, male: 71%) diagnosed with NSTE-ACS underwent echocardiography evaluation at hospital admission and ICA within 24 hours. Culprit vessels were left anterior descending (LAD), left circumflex (CX) and right coronary arteries (RCA) in 38.5%, 39.6% and 21.4%, respectively. An increase of affected vessels (1-,2-,3-vessel CAD) was associated with increased WMSI and TLS values. There was a statistically significant difference of both WMSI-LAD, WMSI-CX, WMSI-RCA and TLS-LAD, TLS-CX, TLS-RCA of myocardial segments with underlying severe CAD compared to no CAD (p = 0.001 and p < 0.001, respectively). Moreover, a significant difference of TLS-LAD, TLS-CX, TLS-RCA and WMSI-CX of myocardial segments with an underlying culprit vessel compared to non culprit vessels (p < 0.001, p < 0.001, p = 0.022 and p < 0.001 respectively) was identified. WMSI-LAD and WMSI-RCA did not show statistical significant differences. A regression model revealed that the combination of WMSI + TLS was more accurate compared to WMSI alone in detecting the culprit vessel (LAD p = 0.001, CX p < 0.001, RCA p = 0.019). Conclusion TLS allows an accurate identification of the culprit vessel in NSTE-ACS patients. In addition to WMSI, TLS may be considered as part of routine echocardiography for better clinical assessment in this subset of patients.

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Section: Methodsmentioning

confidence: 99%

Coronary-specific quantification of myocardial deformation by strain echocardiography may disclose the culprit vessel in patients with non-ST-segment elevation acute coronary syndrome

Guaricci¹,

Chiarello²,

Gherbesi

et al. 2022

European Heart Journal Open

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“…In order to describe the number and the severity of the affected myocardial regions, the wall motion score index (WMSI) was calculated by dividing the total of the wall motion scores of each segment by 16. [ 18 ]. We also took the ejection fraction into account for the differentiation between mild (EF≥40%) and severe TTC (EF <40%).…”

Section: Methodsmentioning

confidence: 99%

Takotsubo cardiomyopathy in patients suffering from acute non-traumatic subarachnoid hemorrhage—A single center follow-up study

et al. 2022

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Background Takotsubo cardiomyopathy (TTC) is an important complication of subarachnoid hemorrhage (SAH), that may delay surgical or endovascular treatment and may influence patient outcome. This prospective follow-up study intended to collect data on the prevalence, severity, influencing factors and long-term outcome of TTC in patients suffering from non-traumatic SAH. Methods Consecutive patients admitted with the diagnosis of non-traumatic SAH were included. Intitial assessment consisted of cranial CT, Hunt-Hess, Fisher and WFNS scoring, 12-lead ECG, transthoracic echocardiography (TTE), transcranial duplex sonography and collecting laboratory parameters (CK, CK-MB, cardiac troponin T, NT-proBNP and urine metanephrine and normetanephrine). Diagnosis of TTC was based on modified Mayo criteria. TTC patients were dichotomized to mild and severe forms. Follow-up of TTE, Glasgow Outcome Scale assessment, Barthel’s and Karnofsky scoring occurred on days 30 and 180. Results One hundred thirty six patients were included. The incidence of TTC in the entire cohort was 28.7%; of them, 20.6% and 8.1% were mild and severe, respectively. TTC was more frequent in females (30/39; 77%) than in males (9/39; 23%) and was more severe. The occurrence of TTC was related to mFisher scores and WFNS scores. Although the severity of TTC was related to mFisher score, Hunt-Hess score, WFNS score and GCS, multivariate analysis showed the strongest relationship with mFisher scores. Ejection fraction differences between groups were present on day 30, but disappeared by day 180, whereas wall motion score index was still higher in the severe TTC group at day 180. By the end of the follow-up period (180 days), 70 (74.5%) patients survived in the non-TTC, 22 (81.5%) in the mild TTC and 3 (27%) in the severe TTC group (n = 11) (p = 0.002). At day 180, GOS, Barthel, and Karnofsky outcome scores were higher in patients in the control (non-TTC) and the mild TTC groups than in the severe TTC group. Conclusions Takotsubo cardiomyopathy is a frequent finding in patients with SAH, and severe TTC may be present in 8% of SAH cases. The severity of TTC may be an independent predictor of mortality and outcome at 6 months after disease onset. Therefore, a regular follow-up of ECG and TTE abnormalities is warranted in patients with subrachnoid hemorrhage for early detection of TTC. Trial registration The study was registered at the Clinical Trials Register under the registration number of NCT02659878 (date of registration: January 21, 2016).

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“…Wall motion score index (WMSI) was calculated by assigning value of 1 to 4 for each of 16 segments of LV as follows: normokinetic segment= 1; hypokinetic segment=2; akinetic segment=3; dyskinetic segment=4 [20].…”

Section: Echocardiography Imagingmentioning

confidence: 99%

Mid-regional pro-adrenomedullin and lactate dehydrogenase as predictors of left ventricular remodeling in patients with myocardial infarction treated with percutaneous coronary intervention

Węgiel¹,

Wojtasik-Bakalarz²,

Malinowski³

et al. 2021

Polish Archives of Internal Medicine

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The key finding of our analysis is that lactate dehydrogenase (LDH) and mid-regional proadrenomedullin (MR-proADM) seem to be promising potential biomarkers of left ventricle (LV) function after myocardial infarction (MI). Higher levels of both biomarkers measured in the acute phase of MI were predictors of LV adverse remodeling after six months from MI, a negative process defined as an increase in end-diastolic volume of LV, which could lead to chronic heart failure. On the other hand, higher levels of both biomarkers were associated with reduced chance of occurrence of a favorable phenomenon, called reverse remodeling, which is associated with reduced LV volume and better prognosis. Identification of high-risk patients of LV adverse remodeling is becoming an important issue as acute mortality after MI has steadily decreased and the main impact of ischemia is shifting to chronic LV dysfunction.

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Assessment of LVEF using a new 16-segment wall motion score in echocardiography

Cited by 14 publications

References 27 publications

Coronary-specific quantification of myocardial deformation by strain echocardiography may disclose the culprit vessel in patients with non-ST-segment elevation acute coronary syndrome

Coronary-specific quantification of myocardial deformation by strain echocardiography may disclose the culprit vessel in patients with non-ST-segment elevation acute coronary syndrome

Takotsubo cardiomyopathy in patients suffering from acute non-traumatic subarachnoid hemorrhage—A single center follow-up study

Mid-regional pro-adrenomedullin and lactate dehydrogenase as predictors of left ventricular remodeling in patients with myocardial infarction treated with percutaneous coronary intervention

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