Assessment of Life Quality in Patients With Stage Iib-Iiib Squamous Cell Cervical Cancer Receiving Paclitaxel Cisplatin Chemotherapy Regimen by Eortc QLQ-C30 Questionnaire in Sanglah Hospital Denpasar

Objective: This study was aimed to assess the quality of life (QoL) of the subjects having congestive heart failure (HF) under different domains of life, such as physical, psychological, and social domains, and they started taking the standard care treatment. Methods: The questionnaire-based prospective study was designed to assess the effects of the HF in different domains of life such as social, psychological, physical, or mental. After getting consent from the subjects, health questionnaire was provided to a total of 60 subjects. Results: We found drastic improvements in 24% of total HF cases in terms of physical debility, whereas only 15% patients reported none of the complications during taking standard care therapy. Total 32.5% patients aware of the treatment took and to whom contact in an emergency. Psychological disturbances and life satisfaction were observed in 16.66% and 33.33% cases suffering from HF. Patient compliance means personal life, as well as medication adherence, was observed in only 53.33%. Conclusions: The results obtained from the responses given by the patients in the health questionnaires demonstrated that the HF patients’ needs awareness regarding the therapy precautions that improving the QoL of patients.

Section: Patients' Compliancesupporting

confidence: 90%

Quality of Life Assessment in the Heart Failure Patients Taking Standard Medical Care in Teaching Hospital

Sharma

Akhtar

Tabassum

et al. 2019

“…The European Organization in Research and Treatment of Cancer QOL Questionnaire (EORTC QOL) version 3.0 [21][22][23][24] was used for the assessment of QOL and Common Terminology Criteria for Adverse Events (CTCAE) version 4.0 [25] was used to grade nausea and vomiting. As per the CTCAE guidelines, the severity of nausea is ranked into three grades (1-3) and vomiting into five grades (1-5) with increasing severity.…”

Section: Introductionmentioning

confidence: 99%

Olanzapine Combined With Standard Antiemetic Regimens for Prevention of Chemotherapy Therapy-Induced Nausea and Vomiting: A Single-Center Experience From South India

James

Jose

2017

Objectives: Olanzapine, an antipsychotic agent, exhibits significant antiemetic properties due to its inhibitory activity on neurotransmitters at multiple receptors involved in chemotherapy-induced nausea and vomiting (CINV). CINV can have an immensely negative impact on patient's quality of life (QOL) and daily activities. Our objectives were to determine the effectiveness of adding olanzapine to standard antiemetic regimens for the prevention of CINV in cancer patients and to compare the QOL of such patients with those receiving standard antiemetic regimens. Methods:A prospective, observational, cohort study was done on patients receiving either highly or moderately emetogenic chemotherapy (MEC). The patients who received only the standard antiemetic regimens were considered as the control group and those who received 10 mg of olanzapine once daily on days 1-5 of chemotherapy in addition to the standard antiemetic regimens were considered to be the study group. The patients were assessed for grades of nausea and vomiting using National Cancer Institute common terminology criteria for adverse events and for QOL using European Organization in Research and Treatment of Cancer QOL questionnaire. Results:Patients were evaluated for a total of 168 cycles of chemotherapy. Compared to the control group, the study group patients showed significant improvement in response to acute nausea (p=0.02) but not in acute vomiting (p=0.09). However, response to delayed nausea and vomiting improved significantly (p=0.004 and p=0.05, respectively). The QOL of study group patients showed significant improvement in functional scales and symptom scales (p<0.02). Global health status also increased significantly (p=0.02) in the study group patients. Conclusion:Olanzapine containing pre-medication regimens can reduce acute and delayed nausea and delayed vomiting and improve the QOL of cancer patients receiving highly or moderately emetogenic chemotherapeutic agents as compared to the standard pre-medication regimens.

“…The TAs along with the malignancy itself affect the QOL [16][17][18]. Since TA is a distressing side effect of chemotherapy and can greatly affect the nutrition of the patients, great care must be taken from the initiation of the therapy to prevent the progression of the distress.…”

Section: Resultsmentioning

confidence: 99%

Taste Alteration and Quality of Life of Patients Receiving Chemotherapy

Antony

Pavithran

2017

Objective: The study was conducted with the aim to determine the taste alteration (TA) and its relation with quality of life (QOL) of patients receiving chemotherapy. Methods:The present study was undertaken among 100 patients receiving cancer chemotherapy with the aim of identifying the commonly experienced TA and its relation with QOL of the patients. The patients were selected by convenience sampling from a selected Cancer Institute in Kerala.Results: The study reported that TA was present in all the patients receiving chemotherapy ranging from mild to severe where 50% had moderate and 9% had severe alteration in taste. There were 19% patients who had poor and 45% who had average QOL. The TAs had a moderately negative correlation with QOL (r=−0.51) indicating that an increase in TA decreases the QOL. Conclusion:The study evinces that TA is a common side effect of chemotherapy which often impacts the QOL negatively. Hence, it is essential to understand the types of TA and the specific drug causing it. This will enable the health-care team members to develop treatments for these conditions and educate patients regarding the strategies to be adopted to manage the problem, thereby improving patients' QOL.