Assessment of left ventricular function before and after a percutanous coronary intervention to chronic total coronary occlusion: Doppler tissue imaging study

Shafey, Wessam H El; Montaser, Said Shalaby; Badran, Hala Mahfouz; Gabr, Mahmoud K; Shokry, Khaled; Galassi, Alfredo R.

doi:10.4103/1110-2098.163892

Cited by 5 publications

(13 citation statements)

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“…Thirty‐four observational studies [including two abstracts ] with a total of 2804 patients met our inclusion criteria . Cardiac magnetic resonance imaging (CMR) was used to assess LVEF in nine studies while echocardiography was used in 10 studies . Other studies used left ventriculography or nuclear imaging, or did not specify the method used for assessing LVEF .…”

Section: Resultsmentioning

confidence: 99%

“…Successful CTO PCI was associated with a significant decrease in LVESV (−4.0 mL, 95%CI −6.0, −2.1, P < 0.0001, I 2 = 0%) (Figure ). LVEDV was analyzed in nine studies including 403 patients . Successful CTO PCI was not associated with a decrease in LVEDV (−2.2 mL, 95%CI −5.7 to 1.1, P = 0.19, I 2 = 0%) (Figure ).…”

Section: Resultsmentioning

confidence: 99%

“…Furthermore, in a sensitivity analysis including only studies with documented CTO duration of at least 3 months and follow‐up duration of at least 3 months after CTO PCI (15 studies, 1248 patients), successful CTO PCI remained associated with significant improvement in LVEF (4.3%, 95%CI 3.0, 5.5, P < 0.00001).…”

Section: Resultsmentioning

confidence: 99%

“…Some of the studies included in the meta‐analysis defined “CTOs” as lesions with <3 months occlusion duration, which is the currently accepted threshold for a lesion to be characterized as CTO. When restricting our analyses to studies with documented CTO duration of at least 3 months and with follow up duration of at least 3 months significant improvement in LVEF was shown (4.31%, 95%CI [3.08, 5.55], P < 0.00001) in 1248 patients 15 studies …”

Section: Discussionmentioning

confidence: 99%

“…Cardiac magnetic resonance imaging (CMR) was used to assess LVEF in nine studies [14][15][16][17]29,32,33,40,41 while echocardiography was used in 10 studies. 22,24,26,31,36,37,39,[43][44][45] Other studies used left ventriculography 13,20,21,23,25,28,34,35,42,46 or nuclear imaging, 27,38 or did not specify the method used for assessing LVEF. 18,19,30 The…”

Section: Characteristics Of the Included Studies And Quality Assessmentioning

confidence: 99%

See 4 more Smart Citations

Meta‐analysis of the impact of successful chronic total occlusion percutaneous coronary intervention on left ventricular systolic function and reverse remodeling

Megaly

Saad

Tajti

et al. 2018

J Interven Cardiology

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Characteristics Of the Included Studies And Quality Assessmentioning

confidence: 99%

See 3 more Smart Citations

Meta‐analysis of the impact of successful chronic total occlusion percutaneous coronary intervention on left ventricular systolic function and reverse remodeling

Megaly

Saad

Tajti

et al. 2018

J Interven Cardiology

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show abstract

Echocardiographic assessment of left ventricular function recovery post percutaneous coronary intervention of chronic total occlusions in patients with low and mid‐range left ventricular ejection fractions

et al. 2020

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Objectives Coronary chronic total occlusion (CTO) is a frequent condition encountered in cardiac catheterization laboratory with a prevalence of about 20%. Through literature, data are scarcely reported regarding the left ventricular (LV) function recovery post CTO percutaneous coronary intervention (PCI) in patients with low (<40%) and mid‐range (40%‐49%) LV ejection fraction (LVEF). The aim of this study was to assess the echocardiographic outcomes of CTO patients with low and mid‐range LVEF successfully revascularized at 6‐month follow‐up. Methods This prospective study included 75 patients with at least one CTO of an epicardial coronary artery proved by previous diagnostic coronary angiography with PCI attempt indication, and successfully revascularized. They were equally divided according to LVEF into three groups, and echocardiographic remodeling indices were assessed at baseline and 6 months post PCI. Results Our study showed significant improvement of LVEF, S‐wave velocity by tissue doppler imaging (TDI), LV wall‐motion score (LVWMS), and LV systolic sphericity index (LVSIS) 6 months post CTO PCI in low LVEF group, and a significant improvement in LVEF, S‐wave velocity, and LVWMS in mid‐range LVEF group (P < .05). The delta change in LVEF was significantly more in low LVEF group, compared to the other two groups (F = 4.739, P < .05). Conclusion Successful CTO PCI in patients with low and mid‐range LVEF is associated with significant improvement of LVEF and other indices of myocardial remodeling after 6 months of follow‐up.

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Assessment of LV Function by Three-Dimensional and Three-Dimensional Speckle Tracking Echocardiography after Percutaneous Coronary Intervention for Chronic Total Occlusion Coronary Artery Disease

Mahgoub

2019

The Egyptian Journal of Hospital Medicine

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Background: Cardiovascular disease is the most leading cause of morbidity and mortality throughout the world today. Chronic total occlusions are defined as 100% occlusions with TIMI flow 0 with at least 3-month duration. New echocardiographic techniques is an important noninvasive method for assessing cardiovascular function and mechanics. Objective: Determination of the impact of revascularization for chronic total occlusion coronary artery disease on left ventricular function using three-dimensional and three-dimensional speckle tracking echocardiography. Patients and methods: The present study included (60) patients presenting with chronic total occlusion coronary artery disease at Al-Azhar University Hospitals, in the period between December 2015 and April 2018. The study compared the differences in echocardiographic parameters before the procedure (pre-procedure) and one month after successful PCI to CTO (post-procedure). Two-dimensional (2D) and three-dimensional (3D) transthoracic echocardiography (baseline and follow up study), 2D Global longitudinal strain (GLS) and 3D longitudinal strain (LS) speckle tracking echocardiography (base line and follow up study) were done. Results: Mean left ventricular ejection fraction significantly increased, while the left ventricular end-diastolic and end-systolic volumes significantly decreased. The left ventricular end-systolic and end-diastolic volumes and diameters were significantly decreased. The global longitudinal strain (2DSTE and 3DSTE) showed significant improvement after successful revascularization. Both patients with LVEF ≥ 50% and LVEF < 50% displayed significant improvement in the 2D GLS and 3D LS, also diabetic and non-diabetic patients displayed significant improvement in the 2D GLS and 3D LS. Improvement in the 2D GLS % was correlated with an improvement in the 3D LS %. Conclusion:Restoring the coronary blood flow in chronic total occlusion patients reduces the left ventricular volumes, dimensions and improves the left ventricular ejection fraction and global longitudinal strain of hibernating myocardium.

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Assessment of left ventricular function before and after a percutanous coronary intervention to chronic total coronary occlusion: Doppler tissue imaging study

Cited by 5 publications

References 1 publication

Meta‐analysis of the impact of successful chronic total occlusion percutaneous coronary intervention on left ventricular systolic function and reverse remodeling

Meta‐analysis of the impact of successful chronic total occlusion percutaneous coronary intervention on left ventricular systolic function and reverse remodeling

Echocardiographic assessment of left ventricular function recovery post percutaneous coronary intervention of chronic total occlusions in patients with low and mid‐range left ventricular ejection fractions

Assessment of LV Function by Three-Dimensional and Three-Dimensional Speckle Tracking Echocardiography after Percutaneous Coronary Intervention for Chronic Total Occlusion Coronary Artery Disease

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