BACKGROUND The principles and methods of biostatistics have gained importance in various fields including dentistry and medicine. The health researchers must have adequate knowledge and understanding of biostatistics to overcome the associated dilemmas in concluding the statistical data. The present study was planned to evaluate the knowledge, attitude, and perception of biostatistics among health researchers in Jeddah, Saudi Arabia. METHODS The present cross-sectional study was questionnaire based and was conducted among 251 health researchers in Saudi Arabia. A convenience method of sampling was followed during the 2 months study period from 15. 08. 2020 to 15. 10. 2020. A pre-validated questionnaire was used that consisted of questions related to the knowledge, attitude and perception of biostatistics. A chi-square test was used to find the significance of study parameters and the level of significance chosen was 5 %. RESULTS Gender, nationality, or qualification of participants did not show any statistically significant differences with regards to their knowledge, attitude, or perception about biostatistics. The years of experience of the faculty showed statistically significant differences in their ability to interpret the results using statistical methods [P = 0.002], ability to choose a particular test to answer research question [P = 0.024], ability to design their projects [P = 0.02], and forming opinions / making decisions in health care using statistical information [P = 0.001]. Nursing and dental faculty were able to design their research projects significantly better when compared to other groups. Faculty of Pharmacy, nursing, and dentistry more frequently used statistical information to form opinions or make decisions in health care when compared to those from the Medical program. CONCLUSIONS The study showed a medium level of knowledge as well as awareness about the importance of statistics in research and indicated a great motivation for further training with an emphasis on teaching and learning biostatistics during undergraduate / postgraduate education. KEY WORDS Biostatistics, Interpret Results, Health Researchers
