2007
DOI: 10.1002/prot.21637
|View full text |Cite
|
Sign up to set email alerts
|

Assessment of intramolecular contact predictions for CASP7

Abstract: Predictions of intramolecular residue-residue contacts were assessed as part of the seventh community-wide Critical Assessment of Structure Prediction experiment (CASP7). As in past assessments, we focused on contacts that lie far apart in sequence as these are likely to be more informative in predicting protein structure. One lab did somewhat better than others according to our assessment, and there is some reason to think that this lab's results represent progress over CASP6. In general, contacts inferred fr… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

2
86
1

Year Published

2007
2007
2010
2010

Publication Types

Select...
4
2

Relationship

1
5

Authors

Journals

citations
Cited by 69 publications
(89 citation statements)
references
References 19 publications
2
86
1
Order By: Relevance
“…In 14 of them, our predictions met the criteria of having at least L/5 (length of given sequence divided by 5) number of predictions for long-distance contacts (>24 residue sequence separation). Due to the lack of a large subset of common targets for which most groups have submitted predictions, no clear ranking of all groups was obtained (Izarzugaza et al, 2007).…”
Section: Structure-based Mode Has Been Ranked As One Of the Three Besmentioning
confidence: 99%
See 3 more Smart Citations
“…In 14 of them, our predictions met the criteria of having at least L/5 (length of given sequence divided by 5) number of predictions for long-distance contacts (>24 residue sequence separation). Due to the lack of a large subset of common targets for which most groups have submitted predictions, no clear ranking of all groups was obtained (Izarzugaza et al, 2007).…”
Section: Structure-based Mode Has Been Ranked As One Of the Three Besmentioning
confidence: 99%
“…The challenge is predicting contacts between residues distant in sequence (sequence separations larger than 12 amino acids). Knowing only a few of these contacts frequently allows the fold of a protein to be defined completely (Baker, 2000;Bonneau et al, 2002a;Izarzugaza et al, 2007).…”
mentioning
confidence: 99%
See 2 more Smart Citations
“…Prediction of intramolecular residue -residue contacts could in principle be helpful for predicting protein structure per se as well as for inferring mutations in the proteins or distinguishing between correct and incorrect protein docking models [35] . This type of prediction is still an area of active research, and continues to be assessed in CASP (starting in CASP4).…”
Section: Other Modeling Categoriesmentioning
confidence: 99%