Assessment of inhibitory potential of Pothos scandens L. on ovalbumin-induced airway hyperresponsiveness in balb/c mice

Pharmacological and Phytochemical Updates on Pothos scandens L

“…The pothobanoside B(2) have shown significant inhibition of histamine release from basophilic cells. Whereas thecurrent study supported by ova induced asthmatic and anti-allergic rhinitis properties of P. scandens ethanolic extract and isolated compound does not show the respective result on the same model reported by Gupta et al 28,29…”

“…Phytochemical analysis of this plant confirms the presence of various phytochemicals like alkaloids, flavonoids, tannins, terpenoids, saponin, catechin, coumarin, phenol, sugar, glycoside and xanthoprotein steroids, proteins, reducing sugars, carbohydrates and cardiac glycosides, phytosterols, fixed oils and fats, gums and mucilage according to standard methods in its different extracts 28,30,31,36 as shown in Table 2. Among leaf, stem and root of P. scandens, the ethanol extract of stem showed better phenolic content as compared to that of leaf and root.…”

“…11 The ethnic people (Kanikaran) of Southern Western Ghats of India use P. scandens leaves mixed with the fruits of Capsicum annuum and rhizome of Allium sativum and the mixture is ground into a paste with coconut oil and applied topically on affected places to healwounds created during delivery. 5,11,28 Chinese people use the plant as blood coagulant for wounds, tumors and drinking for anti-cough. 28 The leaves are used as tea by the Dai ethnic minority.…”

“…5,11,28 Chinese people use the plant as blood coagulant for wounds, tumors and drinking for anti-cough. 28 The leaves are used as tea by the Dai ethnic minority. 37 The powdered leaves are applied to the body to cure small pox, increases milk in cows, stem and leaves are used in snake bites.…”

“…10 Various studies of P. scandens extracts or its constituents showed that the plant possess some of the diverse biological activities like antioxidant, antipyretic, anti-diabetic, free radical scavenging, burn wound healing, anticarcinogenic, anti-estrogenic, hyaluronidase inhibition, histamine release inhibitory, antiseptic, anti-inflammatory, antimicrobial, anticancer, bronchodilator like biological activities of the plant. [10][11][12][25][26][27][28][29][30][31][32][33][34][35][36] Despite of the several use of this plant for ethnomedicinal agent, only a few of compounds were isolated from the plant extracts.…”