Assessment of Infants and Children with Symptoms Suggesting Otitis Media

Nasr, Mona Ramadan; Esayd, Mohamed; Abdelaal, Mohammed Mahmoud

doi:10.4236/oalib.1100693

Cited by 5 publications

(4 citation statements)

References 12 publications

(9 reference statements)

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“…Assessment of Negative Symptoms (SANS) 30 and the Scale for Assessment of Positive Symptoms (SAPS) 31 . Table 1 includes details of patients' psychopathology.…”

Section: Assessment Of Psychopathology Trained Clinicians Rated the mentioning

confidence: 99%

Reduced Resting-State Connectivity in the Precuneus is correlated with Apathy in Patients with Schizophrenia

Forlim

Klock

Bächle

et al. 2020

Sci Rep

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A diagnosis of schizophrenia is associated with a heterogeneous psychopathology including positive and negative symptoms. The disconnection hypothesis, an early pathophysiological framework conceptualizes the diversity of symptoms as a result of disconnections in neural networks. in line with this hypothesis, previous neuroimaging studies of patients with schizophrenia reported alterations within the default mode network (DMN), the most prominent network at rest. The aim of the present study was to investigate the functional connectivity during rest in patients with schizophrenia and with healthy individuals and explore whether observed functional alterations are related to the psychopathology of patients. Therefore, functional magnetic resonance images at rest were recorded of 35 patients with schizophrenia and 41 healthy individuals. Independent component analysis (ICA) was used to extract resting state networks. comparing icA results between groups indicated alterations only within the network of the DMN. More explicitly, reduced connectivity in the precuneus was observed in patients with schizophrenia compared to healthy controls. connectivity in this area was negatively correlated with the severity of negative symptoms, more specifically with the domain of apathy. Taken together, the current results provide further evidence for a role DMN alterations might play in schizophrenia and especially in negative symptoms such as apathy.

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“…Assessment of Negative Symptoms (SANS) 30 and the Scale for Assessment of Positive Symptoms (SAPS) 31 . Table 1 includes details of patients' psychopathology.…”

Section: Assessment Of Psychopathology Trained Clinicians Rated the mentioning

confidence: 99%

Reduced Resting-State Connectivity in the Precuneus is correlated with Apathy in Patients with Schizophrenia

Forlim

Klock

Bächle

et al. 2020

Sci Rep

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“…Negative symptoms were evaluated with the Scale for Negative Symptoms (SANS) and positive symptoms were measured with SAPS (Andreasen, 1984(Andreasen, , 1995Andreasen, 1989). Inter-rater reliabilities for the BPRS, SANS and SAPS total scores were acceptable (к = 0.78, к = 0.76 and к = 0.83, respectively) at the beginning of the study.…”

Section: Clinical Assessmentsmentioning

confidence: 99%

Relationship of negative symptom severity with cognitive symptoms and functioning in subjects at ultra‐high risk for psychosis

Üçok

Direk

Kaya

et al. 2020

Early Intervention Psych

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Aim: Negative symptoms and cognition are related with functioning in schizophrenia. However, it is not clear whether they have a similar effect in individuals at ultra-high risk (UHR) for psychosis. In this study, we aimed to explore relationship of negative symptoms with cognition and functioning cross-sectionally in people with UHR for psychosis.Methods: In total, 107 people participated in this study. We assessed negative symptoms with Scale for Negative Symptoms (SANS). We applied a cognitive battery including seven tests. We evaluated functioning by using Global Assessment of Functioning Scale and work/study status as an indicator of role functioning.Results: SANS scores were correlated to global functioning cross-sectionally. SANS total score was correlated to cognitive test scores related to cognitive flexibility and attention. Only Trail Making Test B (TMT B) was negatively correlated to global functioning. SANS-affective blunting and SANS-avolition scores were independently related to global functioning. There was a significant indirect effect of the TMT B and composite attention scores on global functioning through negative symptoms indicating a complete mediation. Conclusion:Our findings suggest that negative symptoms, particularly avolition have an impact on functioning and the association of cognition with functioning was mediated by negative symptoms in UHR.

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“…Trained clinicians rated the severity of symptoms with the Scale for Assessment of Negative Symptoms (SANS) (Andreasen, 1989) and the Scale for Assessment of Positive Symptoms (SAPS) (Andreasen, 1984). Table 1 includes details of patients' psychopathology.…”

Section: Assessment Of Psychopathologymentioning

confidence: 99%

Reduced Resting-State Connectivity in the Precuneus is correlated with Apathy in Patients with Schizophrenia

Forlim

Klock

Baechle

et al. 2018

Preprint

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A diagnosis of schizophrenia is associated with a heterogeneous psychopathology including positive and negative symptoms. The disconnection hypothesis, an early pathophysiological framework conceptualizes the diversity of symptoms as a result from disconnections in neural networks. In line with this hypothesis, previous neuroimaging studies of patients with schizophrenia reported alterations within the default mode network (DMN), the most prominent network at rest.Aim of the present study was to investigate the functional connectivity during rest in patients with schizophrenia and healthy individuals and explore whether observed functional alterations are related to the psychopathology of patients. Therefore, functional magnetic resonance images at rest were recorded of 35 patients with schizophrenia and 41 healthy individuals. Independent component analysis (ICA) was used to extract resting state networks.Comparing ICA results between groups indicated alterations only within the network of the DMN.More explicitly, reduced connectivity in the precuneus was observed in patients with schizophrenia compared to healthy controls. Connectivity in this area was negatively correlated with the severity of negative symptoms, more specifically with the domain of apathy.Taken together, the current results provide further evidence for a role DMN alterations might play in schizophrenia and especially in negative symptom such as apathy.

show abstract

Assessment of Infants and Children with Symptoms Suggesting Otitis Media

Cited by 5 publications

References 12 publications

Reduced Resting-State Connectivity in the Precuneus is correlated with Apathy in Patients with Schizophrenia

Reduced Resting-State Connectivity in the Precuneus is correlated with Apathy in Patients with Schizophrenia

Relationship of negative symptom severity with cognitive symptoms and functioning in subjects at ultra‐high risk for psychosis

Reduced Resting-State Connectivity in the Precuneus is correlated with Apathy in Patients with Schizophrenia

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