Assessment of in vitro kinetics and biological impact of nebulized trehalose on human bronchial epithelium

Effect of milling and defatting treatment on texture and digestion properties of oat rice

“…During cooking, water permeates the oat rice kernels, resulting in a decrease in bound and free water content and an increase in non-flowing water content. Water penetrates the center of the rice grain, which contains a high concentration of starch particles, which can be connected to free water by hydrogen bonding ( Iskandar et al, 2021 ). At the same time, the protein is usually located at the periphery of the rice grain, and the surface contains many hydrophilic groups, which have a strong affinity for water ( Zhang, Sun, Gao, & Luo, 2022 ).…”

Effects of milling on texture and in vitro starch digestibility of oat rice

“…The peak areas of T 21 , T 22 , and T 23 (M 21 , M 22 , and M 23 ) can represent the signal amplitudes of water in various states. The proportions of M 21 , M 22 , and M 23 to the total area are S 21 , S 22 , and S 23 , respectively, which can indirectly reflect the water in different states and moisture content ( Iskandar et al, 2021 ).…”

“…2 (b) and Table S3 that the bound water content decreases with the milling time increases, meanwhile, the peak position in the corresponding T 2 relaxation spectrum pushes to a longer relaxation time. This result indicates that the strength of organic material binding to water generally tends to weaken with the entry of water molecules ( Iskandar, et al, 2021 ).…”

Synthesis and Application of Trehalose Materials

“…In terms of academic research, trehalose has long been used as a stabilizer for a variety of biologics, such as protein and genetic material, viruses, and microorganisms, 123 or as a cryoprotectant for cells and tissues. 124 Moreover, trehalose is being explored as a therapeutic for cancer 125 and metabolic diseases, 126 as an autophagy inducer, 127 and as a stabilizer for nebulized formulations that does not induce toxicity in the lungs, 128 among many other applications. However, in the past decade, poly(trehalose) has emerged as a promising and potentially superior alternative to the sugar alone.…”