Assessment of Immediate Antimicrobial Effect of Miswak Extract and Toothbrush Oncariogenic Bacteria – A Clinical Study

Bhat, Padma K; Kumar, Amit; Sarkar, Soumik

doi:10.1177/2229411220120106

Cited by 21 publications

(20 citation statements)

References 9 publications

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“…Our findings of herbal extracts affectivity against oral pathogens are in consistence with previous reports [7, 8, 27]. Al-Obaida and coauthors declared miswak as an effective oral hygienic tool and found it helpful against different organisms causing oral cavity infections [28, 29].…”

Section: Discussionsupporting

confidence: 91%

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Detection of antibacterial activities of Miswak, Kalonji and Aloe vera against oral pathogens & anti-proliferative activity against cancer cell line

Amjed

Junaid

Jafar

et al. 2017

BMC Complement Altern Med

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Background: Emerging drug resistance and hindrance of treatment is provoking scientists to search new, less expensive medicinally active compounds. Dental diseases caused by oral pathogens are very frequent chronic infections around the world. The medical potentials of a lot of Pakistani local herbs and herbal combinations is relatively unknown, hence attempted to explore. A study was designed to investigate potential role of local medicinal herbs for example Miswak, Kalonji & Aloe vera as antimicrobial, antioxidant and anti-proliferative agents against oral pathogens and cancer cell line.Methods: Medicinal extracts were prepared in solvents of different polarities. Their antimicrobial activity was determined alone and in combination against oral pathogens. Antioxidant activity was evaluated through Catalase and Superoxide dismutase assay and anti-proliferative activity was evaluated through 3-(4, 5-Dimethylthiazol-2-Yl)-2,5-Diphenyltetrazolium Bromide) assay. Results: Plant extracts alone and in combinations were found significantly effective as antimicrobial agent against standard ATCC strains of C. albicans and S. aureus (P ˂0.001). Especially Miwak extract was found highly significant against fungus. Extracts of Kalonji were found significant in inhibiting growth of HeLa cell lines. Miswak and Kalonji showed significant levels of antioxidant activity. Conclusion:Medicinal herbs Miswak and Kalonji have potential to be used for therapeutic purposes. Results suggested that herbal medicinal composition can be prepared using these extracts after applying scientific standardization methods.

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Section: Discussionsupporting

confidence: 91%

“…It is reported to have antibacterial, antifungal, antioxidant and anticancer properties [7, 8]. Aloe vera is a medicinal herb whose mucilaginous gel is traditionally used to treat different diseases.…”

Section: Introductionmentioning

confidence: 99%

Detection of antibacterial activities of Miswak, Kalonji and Aloe vera against oral pathogens & anti-proliferative activity against cancer cell line

Amjed

Junaid

Jafar

et al. 2017

BMC Complement Altern Med

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“…mutans strains were considered in the study as they are most commonly implicated microorganisms in the causation of dental caries [17]. Mitis Salivarius Bacitracin agar was used for inoculation of S. mutans as it is considered to be a standard media to be used for respective strains [18].…”

Section: Discussionmentioning

confidence: 99%

A Comparison of Antibacterial Efficacy of 0.5% Sodium Fluoride Impregnated Miswak and Plain Miswak Sticks on Streprococcus mutan s - A Randomized Controlled Trial

Raina

Kumar²,

Krishna

et al. 2017

JCDR

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“…When the beneficial effect of S. persica Miswak was compared with synthetic toothbrushes, Miswak was found to be more effective than the synthetic one for oral hygiene and treat gum inflammation [25,[29][30][31].…”

Section: Discussionmentioning

confidence: 99%

Antibacterial activity of Miswak Salvadora persica extracts against isolated and genetically identified oral cavity pathogens

Hesham

Alrumman

2016

THC

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Abstract. BACKGROUND: Despite medical progress worldwide, dental caries are still widespread. Miswak is derived from the plant Arak (Salvadora persica). It is used by Muslim peoples as a natural product for the cleansing of teeth, to ensure oral and dental hygiene. OBJECTIVE: This study was conducted to evaluate the antimicrobial effects of ethanol, methanol, and ethanol/methanol extracts of Miswak against three bacterial pathogens of the oral cavity. METHODS: The pathogens were isolated from the oral cavity of volunteers/patients and were identified on the basis of 16S rRNA gene amplification data. Sequence comparisons were made with 16S rRNA gene sequences available in the GenBank database. RESULTS:The results of sequence alignment and phylogenetic analysis identified the three pathogens as being Staphylococcus aureus strain KKU-020, Enterococcus faecalis strain KKU-021 and Klebsiella pneumoniae strain KKU-022. All Miswak extracts showed powerful antimicrobial activity against the three pathogens. The maximum zone of inhibition (40.67 ± 0.88 mm) was observed against E. faecalis KKU-021 with ethanolic extracts whilst methanolic extracts showed the minimum zone of inhibition (10.33 ± 0.88 mm) against K. pneumonia KKU-022. CONCLUSION: Based upon the significant effects of the Miswak extracts, against the oral cavity pathogens in our study, we recommend that Miswak could be used as a dental hygiene method to prevent tooth caries.

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Assessment of Immediate Antimicrobial Effect of Miswak Extract and Toothbrush Oncariogenic Bacteria – A Clinical Study

Cited by 21 publications

References 9 publications

Detection of antibacterial activities of Miswak, Kalonji and Aloe vera against oral pathogens & anti-proliferative activity against cancer cell line

Detection of antibacterial activities of Miswak, Kalonji and Aloe vera against oral pathogens & anti-proliferative activity against cancer cell line

A Comparison of Antibacterial Efficacy of 0.5% Sodium Fluoride Impregnated Miswak and Plain Miswak Sticks on Streprococcus mutan s - A Randomized Controlled Trial

Antibacterial activity of Miswak Salvadora persica extracts against isolated and genetically identified oral cavity pathogens

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